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37 Matching Annotations

Nov 2025
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CDK7 is a novel therapeutic target in fibrolamellar carcinoma

1
1. scibot 22 Nov 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.isci.2025.113925
  
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sciencedirect.com/science/article/pii/S2589004225021868
Sep 2025
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Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

1
1. scibot 25 Sep 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2025.116185
  
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sciencedirect.com/science/article/pii/S2211124725009568
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RNA Pol II inhibition activates cell death independently from the loss of transcription

1
1. scibot 19 Aug 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.cell.2025.07.034
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406974/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PRPS activity tunes redox homeostasis in Myc-driven lymphoma

1
1. scibot 18 Jun 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.redox.2025.103649
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
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Targeting CDK7/12/13 functional synergism reverses myofibroblast activation and ameliorates lung fibrosis

1
1. scibot 13 Jun 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.isci.2025.112778
  
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sciencedirect.com/science/article/pii/S2589004225010399
May 2025
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U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation

1
1. scibot 18 May 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2025.04.021
  
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sciencedirect.com/science/article/pii/S1097276525003636
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Chromatin-bound U2AF2 splicing factor ensures exon inclusion

1
1. scibot 18 May 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2025.04.013
  
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sciencedirect.com/science/article/pii/S1097276525003168
Apr 2025
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Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis

1
1. scibot 05 Apr 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2025.03.009
  
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sciencedirect.com/science/article/pii/S1097276525002023
Mar 2025
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Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

1
1. scibot 06 Mar 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2025.02.007
  
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sciencedirect.com/science/article/pii/S1097276525001339
Feb 2025
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PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.stem.2025.01.010
  
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sciencedirect.com/science/article/pii/S1934590925000104
Dec 2024
www.cell.com www.cell.com

Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module

1
1. scibot 03 Dec 2024
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2024.09.001
  
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cell.com/molecular-cell/fulltext/S1097-2765(24)00734-2
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The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release

1
1. scibot 02 Dec 2024
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2024.10.046
  
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sciencedirect.com/science/article/pii/S1097276524008852
Sep 2024
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MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer

1
1. scibot 25 Sep 2024
  
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  RRID:AB_2799721
  
  DOI: 10.1016/j.ccell.2020.04.016
  
  Resource: (Cell Signaling Technology Cat# 67221, RRID:AB_2799721)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2799721
  
  Curator comments: Phospho-Rpb1 CTD (Ser5) (D9N5I) Rabbit mAb antibody Cell Signaling Technology Cat# 13523
  
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  RRIDCUR:Incorrect RRID:AB_2799721 RRID:AB_2798246
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sciencedirect.com/science/article/pii/S1535610820302154
Jul 2024
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Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms

1
1. scibot 19 Jul 2024
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2024.114414
  
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sciencedirect.com/science/article/pii/S2211124724007435
Apr 2024
www.cell.com www.cell.com

Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence

1
1. scibot 18 Apr 2024
  
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  AB_2798246
  
  DOI: 10.1016/j.stem.2024.03.015
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(24)00096-1
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SAFB restricts contact domain boundaries associated with L1 chimeric transcription

1
1. scibot 11 Apr 2024
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2024.03.021
  
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sciencedirect.com/science/article/pii/S1097276524002314
Mar 2024
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Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function

1
1. scibot 15 Mar 2024
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2024.113964
  
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sciencedirect.com/science/article/pii/S2211124724002924
Feb 2024
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Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA

1
1. scibot 29 Feb 2024
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2024.113888
  
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sciencedirect.com/science/article/pii/S221112472400216X
Oct 2023
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Protocol for rapidly inducing genome-wide RNA Pol II hyperphosphorylation by selectively disrupting INTAC phosphatase activity

2
1. scibot 22 Oct 2023
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.xpro.2023.102640
  
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  RRID:AB_2798246
2. scibot 22 Oct 2023
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.xpro.2023.102640
  
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sciencedirect.com/science/article/pii/S266616672300607X
52.53.155.43 52.53.155.43

PIIS0092867423009650-html.html

1
1. scibot 06 Oct 2023
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.cell.2023.08.032
  
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52.53.155.43/10a4fc8c2567a3934d6a2c0730d82b14865b6e30/PIIS0092867423009650-html.html
Jul 2023
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Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1

1
1. scibot 06 Jul 2023
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2023.06.007
  
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sciencedirect.com/science/article/pii/S1097276523004306
Jun 2023
www.embopress.org www.embopress.org

DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres

1
1. scibot 22 Jun 2023
  
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  RRID:AB_2798246
  
  DOI: 10.15252/embr.202256492
  
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embopress.org/doi/10.15252/embr.202256492
May 2023
elifesciences.org elifesciences.org

Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction

1
1. scibot 21 May 2023
  
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  RRID:AB_2798246
  
  DOI: 10.7554/eLife.82057
  
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elifesciences.org/articles/82057
Apr 2023
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RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits

1
1. scibot 27 Apr 2023
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2023.02.028
  
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sciencedirect.com/science/article/pii/S1097276523001557
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INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II

1
1. scibot 20 Apr 2023
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2023.03.022
  
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sciencedirect.com/science/article/pii/S1097276523002125
Dec 2022
academic.oup.com academic.oup.com

Dual Acting Peptides Target EZH2 and AR: a New Paradigm for Effective Treatment of Castration-Resistant Prostate Cancer

1
1. scibot 03 Dec 2022
  
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  RRID:AB_2798246
  
  DOI: 10.1210/endocr/bqac180
  
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academic.oup.com/endo/article/164/1/bqac180/6775160
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SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia

1
1. scibot 01 Dec 2022
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2022.111727
  
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sciencedirect.com/science/article/pii/S2211124722016059
Jun 2022
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Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy

1
1. scibot 10 Jun 2022
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.cell.2022.04.031
  
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sciencedirect.com/science/article/pii/S0092867422005293
Apr 2022
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RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex

1
1. scibot 27 Apr 2022
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2022.110732
  
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sciencedirect.com/science/article/pii/S2211124722004934
Sep 2021
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SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape

1
1. scibot 17 Sep 2021
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.molcel.2021.08.029
  
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sciencedirect.com/science/article/pii/S1097276521006961
Jul 2021
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RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control

1
1. scibot 28 Jul 2021
  
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  Pol II Ser5P
  
  DOI: 10.1016/j.molcel.2019.05.007
  
  Resource: (Cell Signaling Technology Cat# 13523, RRID:AB_2798246)
  
  Curator: @ethanbadger
  
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  RRID:AB_2798246 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276519303600
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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

1
1. scibot 27 Jul 2021
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.ccell.2019.09.004
  
  Resource: (Cell Signaling Technology Cat# 13523, RRID:AB_2798246)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Unresolved RRID:AB_2798246 RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S1535610819304246
May 2021
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The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation

1
1. scibot 06 May 2021
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.immuni.2020.07.012
  
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sciencedirect.com/science/article/pii/S1074761320303198
Apr 2021
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Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma

1
1. scibot 28 Apr 2021
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2021.109013
  
  Resource: (Cell Signaling Technology Cat# 13523, RRID:AB_2798246)
  
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sciencedirect.com/science/article/pii/S2211124721003272
Dec 2020
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CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci

1
1. scibot 24 Dec 2020
  
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  RRID:AB_2798246
  
  DOI: 10.1016/j.celrep.2020.108545
  
  Resource: (Cell Signaling Technology Cat# 13523, RRID:AB_2798246)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2798246
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2798246
Visit annotations in context

Tags

RRID:AB_2798246

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720315345
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma

1
1. scibot 04 Sep 2020
  
  in Public
  
  phospho-Rbp1 CTD (Ser5) rabbit mAb
  
  DOI: 10.1016/j.celrep.2020.03.049
  
  Resource: (Cell Signaling Technology Cat# 13523, RRID:AB_2798246)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798246
  
  What is this?
  
  RRID:AB_2798246 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_2798246

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720303636