Hypothesis

35 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

STING engages PKR to drive lysosomal cell death in lung ischemia-reperfusion injury

1
1. scibot 15 Oct 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.molcel.2026.09.024
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276526006672
Oct 2026
www.sciencedirect.com www.sciencedirect.com

CAR-engineered microglia harness phagocytosis to target brain tumor in organoid models

1
1. scibot 08 Oct 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2026.118091
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726011708
Sep 2026
www.sciencedirect.com www.sciencedirect.com

Mitochondrial Fis1 tunes Rab7A activity via TBC1D15 modulating STING degradation

1
1. scibot 11 Sep 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2026.117994
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726010727
Jul 2026
www.sciencedirect.com www.sciencedirect.com

TTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescence

1
1. scibot 20 Jul 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2026.117703
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726007813
Apr 2026
www.science.org www.science.org

Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex

1
1. scibot 02 Apr 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1126/sciadv.adx8715
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

science.org/doi/10.1126/sciadv.adx8715
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex

1
1. scibot 24 Mar 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1126/sciadv.adx8715
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13004025/
Feb 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226004311-main-html.html

1
1. scibot 19 Feb 2026
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.isci.2026.115056
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

54.241.53.176/ec848ac32c78cddfb23f9dab7afd5557beac8c82/1-s2.0-S2589004226004311-main-html.html
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The E3 ubiquitin ligase Trip12 semi-selectively attenuates Wnt signaling

1
1. scibot 16 Oct 2025
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.isci.2025.113575
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12519312/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis

1
1. scibot 06 Sep 2025
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.isci.2025.113408
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004225016694
Feb 2025
www.sciencedirect.com www.sciencedirect.com

ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.cell.2025.01.027
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867425000960
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists

1
1. scibot 01 May 2024
  
  in Public
  
  AB_2798750
  
  DOI: 10.1101/2024.04.19.590338
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A mechanism linking p53-mediated ferroptosis and NCOA4-mediated ferritinophagy in melatonin-related improvement of diabetic brain injury

1
1. scibot 13 Apr 2024
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.isci.2024.109511
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10987905/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport

1
1. scibot 14 Feb 2024
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.ijbiomac.2024.130055
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0141813024008584
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Lysosomal dynamics regulate mammalian cortical neurogenesis

1
1. scibot 16 Dec 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.devcel.2023.11.021
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580723006196
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.molcel.2023.08.032
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276523006950
www.sciencedirect.com www.sciencedirect.com

TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

1
1. scibot 07 Sep 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2023.113070
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723010811
Jun 2023
www.sciencedirect.com www.sciencedirect.com

ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation

1
1. scibot 23 Jun 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.chembiol.2023.05.010
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945623001538
www.sciencedirect.com www.sciencedirect.com

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

1
1. scibot 16 Jun 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.molcel.2023.05.018
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727652300374X
Mar 2023
www.sciencedirect.com www.sciencedirect.com

TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

1
1. scibot 22 Mar 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.jbc.2023.104621
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0021925823002636
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Targeting VPS41 induces methuosis and inhibits autophagy in cancer cells

1
1. scibot 28 Jan 2023
  
  in Public
  
  AB_2798750
  
  DOI: 10.1016/j.chembiol.2023.01.002
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945623000235
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 14 Jan 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1111/bph.15997
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15997
www.sciencedirect.com www.sciencedirect.com

SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2

1
1. scibot 12 Jan 2023
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2022.111984
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722018885
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Rapid macropinocytic transfer of α-synuclein to lysosomes

1
1. scibot 27 Jul 2022
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2022.111102
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722009044
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration

1
1. scibot 13 Feb 2022
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.isci.2022.103842
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222001122
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

1
1. scibot 24 Nov 2021
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1038/s41419-021-04372-6
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8599682/
Oct 2021
elifesciences.org elifesciences.org

Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

1
1. scibot 23 Oct 2021
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.7554/eLife.72328
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

elifesciences.org/articles/72328
Jul 2021
www.nature.com www.nature.com

Regulation of the endosomal SNX27-retromer by OTULIN

1
1. scibot 30 Jul 2021
  
  in Public
  
  anti-LAMP1
  
  DOI: 10.1038/s41467-019-12309-z
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Missing

Annotators

scibot

URL

nature.com/articles/s41467-019-12309-z
May 2021
www.sciencedirect.com www.sciencedirect.com

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

1
1. scibot 06 May 2021
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.devcel.2020.11.016
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750
Visit annotations in context

Tags

RRID:AB_2798750

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580720309254
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.devcel.2021.03.032
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721003075
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

1
1. scibot 26 Nov 2020
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.7554/eLife.55547
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7673780/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Regulation of Autophagic Flux by the 20S Proteasome

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.chembiol.2019.07.002
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619302107
www.sciencedirect.com www.sciencedirect.com

Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.chom.2019.08.017
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1931312819304263
www.sciencedirect.com www.sciencedirect.com

Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.cell.2019.07.002
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S009286741930741X
www.sciencedirect.com www.sciencedirect.com

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2019.06.079
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719308599
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2798750
  
  DOI: 10.1016/j.celrep.2019.04.070
  
  Resource: (Cell Signaling Technology Cat# 15665, RRID:AB_2798750)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798750
  
  What is this?
  
  RRID:AB_2798750 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2798750

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719305431