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A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state

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Jun 2026
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Explosive cytotoxicity of ruptoblasts bridges hormone surveillance and immune defense

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May 2026
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Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitors

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Mar 2026
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MerTK-triggered TGFβ1 autocrine signal regulates microglial response to neurodegeneration

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Jan 2026
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Dingal-Molecularmechanismscontrolling-2023-html.html

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Oct 2025
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The distinct roles of TGF-β signaling in retinal development

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Jun 2025
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The matricellular protein ADAMTS-like 2 regulates differentiation of skeletal muscle-resident fibro-adipogenic progenitor cells

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Protocol for immunofluorescence detection and quantification of phosphorylated SMAD proteins in human blastocysts

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May 2025
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Optogenetic control of Nodal signaling patterns

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pmc.ncbi.nlm.nih.gov/articles/PMC12070070/
Feb 2025
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TGF-β signaling controls neural crest developmental plasticity via SMAD2/3

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TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion

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LRRC75A-AS1 drives the epithelial-mesenchymal transition in cervical cancer by binding IGF2BP1 and inhibiting SYVN1-mediated NLRP3 ubiquitination

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aacrjournals.org/mcr/article/22/12/1075/750095/LRRC75A-AS1-Drives-the-Epithelial-Mesenchymal
Jan 2025
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TWEAK-Fn14 signaling protects mice from pulmonary fibrosis by inhibiting fibroblast activation and recruiting pro-regenerative macrophages

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  DOI: 10.1016/j.celrep.2024.115220
  
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Dec 2024
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Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence

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Nov 2024
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Vitamin D alleviates HFD-induced hepatic fibrosis by inhibiting DNMT1 to affect the TGFβ1/Smad3 pathway

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May 2024
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mcr-23-0478-html.html

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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease

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1. scibot 01 May 2024
  
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Apr 2024
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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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mcr-23-0478-html.html

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Feb 2024
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EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

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biorxiv.org/content/10.1101/2023.12.05.570182v1
Dec 2023
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FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression

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sciencedirect.com/science/article/pii/S2589004223026573
Nov 2023
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Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1

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pnas.org/doi/abs/10.1073/pnas.2307203120
Oct 2023
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Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity

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Sep 2023
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ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer

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  DOI: 10.1158/0008-5472.CAN-23-0067
  
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Jul 2023
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Organ function is preserved despite reorganization of niche architecture in the hair follicle

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can-23-0067-html.html

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Jun 2023
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Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer

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May 2023
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BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage

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  DOI: 10.1242/dev.201450
  
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Ex utero monkey embryogenesis from blastocyst to early organogenesis

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  DOI: 10.1016/j.cell.2023.04.020
  
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Apr 2023
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IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma

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  DOI: 10.1016/j.isci.2023.106639
  
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Feb 2023
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Exosomes mediated fibrogenesis in dilated cardiomyopathy through a MicroRNA pathway

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  DOI: 10.1016/j.isci.2023.105963
  
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Dec 2022
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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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  DOI: 10.1016/j.ccell.2022.11.005
  
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STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.

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  DOI: 10.1016/j.jcmgh.2022.09.006
  
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Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors

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  DOI: 10.1016/j.diff.2022.09.002
  
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Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth

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Nov 2021
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Modulating mesendoderm competence during human germ layer differentiation

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  DOI: 10.1016/j.celrep.2021.109990
  
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Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells

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TNAP is a novel regulator of cardiac fibrosis after myocardial infarction by mediating TGF-β/Smads and ERK1/2 signaling pathways

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May 2021
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Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition

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  DOI: 10.3892/or.2020.7463
  
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Aging Reprograms the Hematopoietic-Vascular Niche to Impede Regeneration and Promote Fibrosis

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Capturing human trophoblast development with naive pluripotent stem cells in vitro

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Mar 2021
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

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Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals

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Sep 2020
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BPS Publications

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  DOI: 10.1111/bph.15010
  
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