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ZD-4009, a Novel BCL9 Inhibitor, Is Associated with Ameliorated Pulmonary Fibrosis and Reduced HIF-1α-Mediated Glycolysis and TGF-β/SMAD Signaling

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1. scibot 27 Jul 2026
  
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  DOI: 10.1016/j.molpha.2026.100144
  
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sciencedirect.com/science/article/pii/S0026895X26000441
Jul 2026
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TGFβ determines epithelial tissue spacing by regulating mesenchymal condensation

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1. scibot 15 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117683
  
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sciencedirect.com/science/article/pii/S2211124726007618
Jun 2026
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A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.015
  
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sciencedirect.com/science/article/pii/S1074761326002268
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Explosive cytotoxicity of ruptoblasts bridges hormone surveillance and immune defense

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1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.cell.2026.05.008
  
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sciencedirect.com/science/article/pii/S0092867426005672
May 2026
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Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitors

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1. scibot 20 May 2026
  
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  DOI: 10.1038/s41467-026-70957-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13168655/
Mar 2026
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MerTK-triggered TGFβ1 autocrine signal regulates microglial response to neurodegeneration

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1. scibot 18 Mar 2026
  
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  DOI: 10.1038/s41467-026-69189-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12976283/
Jan 2026
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Dingal-Molecularmechanismscontrolling-2023-html.html

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1. scibot 06 Jan 2026
  
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54.241.53.176/057d519796449ae79927acf8096840284e185810/Dingal-Molecularmechanismscontrolling-2023-html.html
Oct 2025
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The distinct roles of TGF-β signaling in retinal development

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113737
  
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sciencedirect.com/science/article/pii/S2589004225019984
Jun 2025
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The matricellular protein ADAMTS-like 2 regulates differentiation of skeletal muscle-resident fibro-adipogenic progenitor cells

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112712
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12164049/
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Protocol for immunofluorescence detection and quantification of phosphorylated SMAD proteins in human blastocysts

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1. scibot 05 Jun 2025
  
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  DOI: 10.1016/j.xpro.2025.103849
  
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sciencedirect.com/science/article/pii/S2666166725002552
May 2025
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Optogenetic control of Nodal signaling patterns

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1. scibot 21 May 2025
  
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  DOI: 10.1242/dev.204506
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12070070/
Feb 2025
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TGF-β signaling controls neural crest developmental plasticity via SMAD2/3

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1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.018
  
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sciencedirect.com/science/article/pii/S1534580725000590
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TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115315
  
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sciencedirect.com/science/article/pii/S2211124725000865
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LRRC75A-AS1 drives the epithelial-mesenchymal transition in cervical cancer by binding IGF2BP1 and inhibiting SYVN1-mediated NLRP3 ubiquitination

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1. scibot 14 Feb 2025
  
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  DOI: 10.1158/1541-7786.MCR-23-0478
  
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aacrjournals.org/mcr/article/22/12/1075/750095/LRRC75A-AS1-Drives-the-Epithelial-Mesenchymal
Jan 2025
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TWEAK-Fn14 signaling protects mice from pulmonary fibrosis by inhibiting fibroblast activation and recruiting pro-regenerative macrophages

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1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115220
  
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sciencedirect.com/science/article/pii/S2211124724015717
Dec 2024
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Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence

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1. scibot 11 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111311
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11617384/
Nov 2024
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Vitamin D alleviates HFD-induced hepatic fibrosis by inhibiting DNMT1 to affect the TGFβ1/Smad3 pathway

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1. scibot 15 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111262
  
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sciencedirect.com/science/article/pii/S2589004224024878
May 2024
52.53.155.43 52.53.155.43

mcr-23-0478-html.html

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1. scibot 23 May 2024
  
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  DOI: 10.1158/1541-7786.mcr-23-0478
  
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2. scibot 23 May 2024
  
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52.53.155.43/a4d1b1195ce648b46cbdc2b7d1e41b22ba16f57e/mcr-23-0478-html.html
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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.stem.2024.04.002
  
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sciencedirect.com/science/article/pii/S1934590924001292
Apr 2024
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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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1. scibot 24 Apr 2024
  
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  DOI: 10.1093/narcan/zcae018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
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mcr-23-0478-html.html

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52.53.155.43/a4d1b1195ce648b46cbdc2b7d1e41b22ba16f57e/mcr-23-0478-html.html
Feb 2024
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EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

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1. scibot 09 Feb 2024
  
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sciencedirect.com/science/article/pii/S2211124724000421
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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

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1. scibot 09 Feb 2024
  
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  RRID:AB_2798798
  
  DOI: 10.1101/2023.12.05.570182
  
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  DOI: 10.1101/2023.12.05.570182
  
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biorxiv.org/content/10.1101/2023.12.05.570182v1
Dec 2023
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FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108580
  
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sciencedirect.com/science/article/pii/S2589004223026573
Nov 2023
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Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1

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1. scibot 18 Nov 2023
  
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  DOI: 10.1073/pnas.2307203120
  
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pnas.org/doi/abs/10.1073/pnas.2307203120
Oct 2023
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Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity

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1. scibot 17 Oct 2023
  
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  DOI: 10.1186/s12967-023-04542-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10577912/
Sep 2023
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ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer

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1. scibot 20 Sep 2023
  
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  DOI: 10.1158/0008-5472.CAN-23-0067
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10502452/
Jul 2023
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Organ function is preserved despite reorganization of niche architecture in the hair follicle

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1. scibot 12 Jul 2023
  
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  DOI: 10.1016/j.stem.2023.06.003
  
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can-23-0067-html.html

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  DOI: 10.1158/0008-5472.can-23-0067
  
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52.53.155.43/1af2a0d742419295c56fc417c605df7b31cfe676/can-23-0067-html.html
Jun 2023
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Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.ccell.2023.05.016
  
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sciencedirect.com/science/article/pii/S1535610823001836
May 2023
52.53.155.43 52.53.155.43

BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage

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1. scibot 19 May 2023
  
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  DOI: 10.1242/dev.201450
  
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52.53.155.43/dd2974174e67d65ed3a779c744ae7b3f60cd7f18/RRID11-html.html
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Ex utero monkey embryogenesis from blastocyst to early organogenesis

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.020
  
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sciencedirect.com/science/article/pii/S0092867423004166
Apr 2023
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IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106639
  
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Exosomes mediated fibrogenesis in dilated cardiomyopathy through a MicroRNA pathway

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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.

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Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors

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Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth

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Modulating mesendoderm competence during human germ layer differentiation

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Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells

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TNAP is a novel regulator of cardiac fibrosis after myocardial infarction by mediating TGF-β/Smads and ERK1/2 signaling pathways

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Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition

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Aging Reprograms the Hematopoietic-Vascular Niche to Impede Regeneration and Promote Fibrosis

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Capturing human trophoblast development with naive pluripotent stem cells in vitro

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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

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Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals

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Sep 2020
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BPS Publications

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