43 Matching Annotations
  1. Apr 2024
  2. link.springer.com link.springer.com
    Hypoxia exposure blunts angiogenic signaling and upregulates the antioxidant system in endothelial cells derived from elephant seals
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1186/s12915-024-01892-3

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    link.springer.com/article/10.1186/s12915-024-01892-3
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
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    Oxygen–Glucose Deprivation Increases NR4A1 Expression and Promotes Its Extranuclear Translocation in Mouse Astrocytes
    1
    1. scibot 03 Apr 2024
      RRID:AB_2936488

      DOI: 10.3390/brainsci14030244

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  5. Mar 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.isci.2024.109340

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945209/
  7. Jan 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
    1
    1. scibot 20 Jan 2024
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      DOI: 10.1016/j.isci.2023.108733

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
  9. www.sciencedirect.com www.sciencedirect.com
    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.016

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    sciencedirect.com/science/article/pii/S1550413123004679
  10. www.sciencedirect.com www.sciencedirect.com
    Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113658

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    sciencedirect.com/science/article/pii/S2211124723016698
  11. Nov 2023
  12. www.embopress.org www.embopress.org
    SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1
    1
    1. scibot 03 Nov 2023
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      DOI: 10.15252/embr.202357500

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    embopress.org/doi/10.15252/embr.202357500
  13. www.sciencedirect.com www.sciencedirect.com
    m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113273

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    sciencedirect.com/science/article/pii/S2211124723012858
  14. Oct 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
    1
    1. scibot 12 Oct 2023
      RRID:AB_2799095

      DOI: 10.26508/lsa.202302148

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    ncbi.nlm.nih.gov/pmc/articles/PMC10556724/
  16. Aug 2023
  17. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    HIF-1α inhibition in macrophages preserves acute liver failure by reducing IL-1β production
    1
    1. scibot 29 Aug 2023
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      DOI: 10.1096/fj.202300428RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202300428RR
  18. 52.53.155.43 52.53.155.43
    HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1
    2
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112945

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    2. scibot 05 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112945

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    52.53.155.43/a33688970e7ada6a5acbf8256b00bc51e343dfea/PIIS2211124723009567-html.html
  19. Jun 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation
    1
    1. scibot 21 Jun 2023
      RRID:AB_2799095

      DOI: 10.1016/j.cmet.2023.05.009

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    sciencedirect.com/science/article/pii/S1550413123001869
  21. www.sciencedirect.com www.sciencedirect.com
    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cmet.2023.05.011

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    sciencedirect.com/science/article/pii/S1550413123002097
  22. Apr 2023
  23. www.sciencedirect.com www.sciencedirect.com
    A tissue injury sensing and repair pathway distinct from host pathogen defense
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.cell.2023.03.031

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    sciencedirect.com/science/article/pii/S0092867423003288
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation
    1
    1. scibot 05 Apr 2023
      RRID:AB_2799095

      DOI: 10.1016/j.isci.2023.106314

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    ncbi.nlm.nih.gov/pmc/articles/PMC10064239/
  25. Jan 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
    1
    1. scibot 04 Jan 2023
      RRID: 2799095

      DOI: 10.1016/j.cmet.2022.12.003

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    sciencedirect.com/science/article/pii/S155041312200540X
  27. Dec 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111756

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    sciencedirect.com/science/article/pii/S2211124722016394
  29. Aug 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111295

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    sciencedirect.com/science/article/pii/S2211124722011159
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1 β-Induced Endothelium Injury
    1
    1. scibot 26 Aug 2022
      RRID:AB_2799095

      DOI: 10.3390/antiox11081455

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    ncbi.nlm.nih.gov/pmc/articles/PMC9394259/
  32. Jul 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111065

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    sciencedirect.com/science/article/pii/S2211124722008634
  34. link.springer.com link.springer.com
    The immunometabolite S-2-hydroxyglutarate exacerbates perioperative ischemic brain injury and cognitive dysfunction by enhancing CD8+ T lymphocyte-mediated neurotoxicity
    1
    1. scibot 09 Jul 2022
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      DOI: 10.1186/s12974-022-02537-4

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    link.springer.com/article/10.1186/s12974-022-02537-4
  35. Jun 2022
  36. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
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    1. scibot 30 Jun 2022
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      DOI: 10.1158/2159-8290.CD-21-1022

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    2. scibot 25 Jun 2022
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      DOI: 10.1158/2159-8290.cd-21-1022

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    3. scibot 25 Jun 2022
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      DOI: 10.1158/2159-8290.cd-21-1022

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    52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
  37. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of sphingolipid synthesis reduces ferroptosis by stimulating the HIF-1 pathway.
    1
    1. scibot 25 Jun 2022
      RRID:AB_2799095

      DOI: 10.1016/j.isci.2022.104533

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    sciencedirect.com/science/article/pii/S2589004222008045
  38. Apr 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium
    1
    1. scibot 27 Apr 2022
      RRID:AB_2799095

      DOI: 10.3390/antiox11040728

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    ncbi.nlm.nih.gov/pmc/articles/PMC9025668/
  40. www.sciencedirect.com www.sciencedirect.com
    Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.cell.2022.03.033

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    sciencedirect.com/science/article/pii/S0092867422003439
  41. aacrjournals.org aacrjournals.org
    Chromatin remodeling induced by ARID1A loss in lung cancer promotes glycolysis and confers JQ1 vulnerability
    1
    1. scibot 05 Apr 2022
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      DOI: 10.1158/0008-5472.CAN-21-0763

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    aacrjournals.org/cancerres/article/82/5/791/681781/Chromatin-Remodeling-Induced-by-ARID1A-Loss-in
  42. Feb 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation
    1
    1. scibot 16 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110391

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    sciencedirect.com/science/article/pii/S2211124722001127
  44. Dec 2021
  45. www.mdpi.com www.mdpi.com
    Transcription Factor ChREBP Mediates High Glucose-Evoked Increase in HIF-1α Content in Epithelial Cells of Renal Proximal Tubules
    1
    1. scibot 29 Dec 2021
      RRID:AB_279909

      DOI: 10.3390/ijms222413299

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      Curator comments: HIF-1α (D1S7W) XP® Rabbit mAb antibody Cell Signaling Technology Cat# 36169

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    mdpi.com/1422-0067/22/24/13299
  46. www.nature.com www.nature.com
    GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure
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      DOI: 10.1038/s41419-021-04394-0

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    nature.com/articles/s41419-021-04394-0
  47. www.sciencedirect.com www.sciencedirect.com
    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.isci.2021.103517

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    sciencedirect.com/science/article/pii/S2589004221014887
  48. Oct 2021
  49. www.sciencedirect.com www.sciencedirect.com
    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
    1
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      DOI: 10.1016/j.celrep.2021.109804

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    sciencedirect.com/science/article/pii/S221112472101264X
  50. Jun 2021
  51. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
    1
    1. scibot 29 Jun 2021
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      DOI: 10.1158/2159-8290.CD-20-1353

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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.12.008

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    sciencedirect.com/science/article/pii/S1934590920305920
  54. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.devcel.2020.07.014

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    sciencedirect.com/science/article/pii/S1534580720305888
  55. www.sciencedirect.com www.sciencedirect.com
    Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer
    1
    1. scibot 01 May 2021
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      DOI: 10.1016/j.cmet.2021.01.018

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    sciencedirect.com/science/article/pii/S1550413121000565
  56. Feb 2021
  57. elifesciences.org elifesciences.org
    The kinase PDK1 is critical for promoting T follicular helper cell differentiation
    1
    1. scibot 25 Feb 2021
      RRID:AB_2799095

      DOI: 10.7554/eLife.61406

      Resource: (Cell Signaling Technology Cat# 36169, RRID:AB_2799095)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2799095

      What is this?
      RRIDCUR:Validated RRID:AB_2799095
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    elifesciences.org/articles/61406
  58. Jan 2021
  59. www.frontiersin.org www.frontiersin.org
    Melatonin Lowers HIF-1α Content in Human Proximal Tubular Cells (HK-2) Due to Preventing Its Deacetylation by Sirtuin 1
    1
    1. scibot 29 Jan 2021
      RRID:AB_279909

      DOI: 10.3389/fphys.2020.572911

      Resource: (Cell Signaling Technology Cat# 36169, RRID:AB_2799095)

      Curator: @evieth

      SciCrunch record: RRID:AB_2799095

      What is this?
      RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:AB_2799095
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    frontiersin.org/article/10.3389/fphys.2020.572911/full
  60. Oct 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pregnancy success in mice requires appropriate cannabinoid receptor signaling for primary decidua formation
    1
    1. scibot 24 Oct 2020
      RRID:AB_2799095

      DOI: 10.7554/eLife.61762

      Resource: AB_2799095

      Curator: @evieth

      SciCrunch record: RRID:AB_2799095

      What is this?
      RRIDCUR:Validated RRID:AB_2799095
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    ncbi.nlm.nih.gov/pmc/articles/PMC7550189/