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Neuroprotectant development from small molecule inhibitors of CHOP/ATF4 expression

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  DOI: 10.1016/j.celrep.2026.118225
  
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sciencedirect.com/science/article/pii/S2211124726013045
Aug 2026
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p97 Inhibition Synergistically Enhances Hypomethylating Therapy Through Targeting of PLK1 in Acute Myeloid Leukemia

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1. scibot 13 Aug 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0035
  
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aacrjournals.org/cancerrescommun/article/6/6/1509/786204/p97-Inhibition-Synergistically-Enhances
Jun 2026
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Exosomal misfolded α1-antitrypsin triggers a cytosolic GRP78-dependent unfolded protein response and pro-survival signaling in pre-metastatic tissues

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1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.jbc.2026.113282
  
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sciencedirect.com/science/article/pii/S002192582602154X
Apr 2026
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Wntless degradation mediated by CaMKII inhibition drives endoplasmic reticulum stress and apoptosis

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1. scibot 15 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117256
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13266901/
Mar 2026
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ALG6 orchestrates coronavirus replication via the endoplasmic reticulum stress-autophagy axis

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117108
  
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sciencedirect.com/science/article/pii/S2211124726001865
Feb 2026
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BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.01.012
  
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sciencedirect.com/science/article/pii/S1097276526000328
Jan 2026
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FAM134B Controls Collagen I Dynamics in Hepatic Stellate Cell-Driven Fibrosis

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1. scibot 28 Jan 2026
  
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  DOI: 10.1152/ajpgi.00170.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12818557/
Dec 2025
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misra-et-al-2025-fam134b-controls-collagen-i-dynamics-in-hepatic-stellate-cell-driven-fibrosis-html.html

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1. scibot 16 Dec 2025
  
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  DOI: 10.6084/m9.figshare.30317422
  
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54.241.53.176/7d61701eda67e5c30e5b80a91af04eaa9e6cd528/misra-et-al-2025-fam134b-controls-collagen-i-dynamics-in-hepatic-stellate-cell-driven-fibrosis-html.html
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circATF6 triggers calcium overload to synergize with EGFR-TKI in non-small cell lung cancer via modulation of proteostasis

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116659
  
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sciencedirect.com:5037/science/article/pii/S2211124725014317
Nov 2025
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Inhibition of Histone Deacetylases Induces Cancer Cell Apoptosis Through the PERK Pathway of ER Stress Response

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1. scibot 01 Nov 2025
  
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  DOI: 10.1111/jcmm.70928
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12571189/
Jul 2025
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Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.027
  
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sciencedirect.com/science/article/pii/S0092867425007287
Jun 2025
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BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.05.035
  
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cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
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Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.jpet.2025.103634
  
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sciencedirect.com/science/article/pii/S0022356525398472
May 2025
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Inhibition of IRE1α Alleviates Renal Fibrosis and Downregulates M1 Macrophage Activation via the p38 MAPK Pathway

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1. scibot 29 May 2025
  
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  DOI: 10.1111/imm.13949
  
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onlinelibrary.wiley.com/doi/10.1111/imm.13949
www.cell.com www.cell.com

IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115694
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00465-6
Jul 2024
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Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114402
  
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sciencedirect.com/science/article/pii/S2211124724007307
May 2024
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NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth

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1. scibot 23 May 2024
  
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  DOI: 10.1158/1541-7786.MCR-23-0445
  
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aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
Mar 2024
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A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

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1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.bbadis.2024.167131
  
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sciencedirect.com/science/article/pii/S0925443924001200
Feb 2024
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A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

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1. scibot 29 Feb 2024
  
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  DOI: 10.1101/2023.10.24.563545
  
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  AB_2799696
  
  DOI: 10.1101/2023.10.24.563545
  
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52.53.155.43/208912a7429960b4182882fc2fcf60d73a185bc4/delete-html.html
Nov 2023
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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113352
  
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sciencedirect.com/science/article/pii/S2211124723013645
Sep 2023
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CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance

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  DOI: 10.1016/j.celrep.2023.113130
  
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sciencedirect.com/science/article/pii/S2211124723011427
Jul 2023
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Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons

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1. scibot 12 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112746
  
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sciencedirect.com/science/article/pii/S221112472300757X
Jan 2023
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A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation

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1. scibot 22 Jan 2023
  
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  DOI: 10.3389/fimmu.2022.1083119
  
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frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1083119/full
Dec 2022
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BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1

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1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.isci.2022.105626
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
Mar 2022
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The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

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  DOI: 10.1016/j.cmet.2022.02.010
  
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sciencedirect.com/science/article/pii/S1550413122000547
Jan 2022
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Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection

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1. scibot 22 Jan 2022
  
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  DOI: 10.1371/journal.pntd.0009192
  
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journals.plos.org/plosntds/article
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AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia

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  DOI: 10.1016/j.celrep.2021.110197
  
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sciencedirect.com/science/article/pii/S2211124721017010
Nov 2021
academic.oup.com academic.oup.com

TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells

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1. scibot 24 Nov 2021
  
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  DOI: 10.1210/endocr/bqab212
  
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academic.oup.com/endo/article/163/1/bqab212/6382455
Oct 2021
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Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival

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1. scibot 15 Oct 2021
  
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  DOI: 10.1016/j.isci.2021.103168
  
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sciencedirect.com/science/article/pii/S2589004221011366
Jan 2021
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A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress

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  DOI: 10.1016/j.celrep.2020.108563
  
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sciencedirect.com/science/article/pii/S2211124720315527
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus

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1. scibot 04 Sep 2020
  
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  DOI: 10.3389/fnagi.2020.00192
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7367218/