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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies
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      DOI: 10.3390/nu16223919

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  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity
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    1. scibot 21 Dec 2024
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    Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease
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    1. scibot 21 Dec 2024
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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00443-8
  5. Dec 2024
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    Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury
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    sciencedirect.com/science/article/pii/S1931312824004086
  7. Sep 2024
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    Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages
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    Granulocyte colony stimulating factor promotes scarless tissue regeneration
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    sciencedirect.com/science/article/pii/S2211124724010933
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    Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation
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    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
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    sciencedirect.com/science/article/pii/S2211383524003733
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    SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation
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    1. scibot 10 Sep 2024
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  13. Aug 2024
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    FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia
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  15. Jul 2024
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    ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells
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    Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
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    1. scibot 18 Jul 2024
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    cell.com/cancer-cell/fulltext/S1535-6108(24)00226-5
  18. Jun 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia
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    1. scibot 21 Jun 2024
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  20. aacrjournals.org aacrjournals.org
    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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    1. scibot 07 Jun 2024
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      DOI: 10.1158/0008-5472.CAN-23-0519

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    aacrjournals.org/cancerres/article/84/11/1834/745520/Obesogenic-High-Fat-Diet-and-MYC-Cooperate-to
  21. May 2024
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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    1. scibot 17 May 2024
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    sciencedirect.com/science/article/pii/S1535610824001351
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    linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
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    sciencedirect.com/science/article/pii/S2211124724005680
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    Monocyte bioenergetics: An immunometabolic perspective in metabolic dysfunction-associated steatohepatitis
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    sciencedirect.com/science/article/pii/S2666379124002568
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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    sciencedirect.com/science/article/pii/S1550413124001359
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    ATGL mediated adipocyte lipolysis exacerbates acute pancreatitis severity in mouse models and patients
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    1. scibot 07 May 2024
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    sciencedirect.com/science/article/pii/S0002944024001652
  28. Apr 2024
  29. www.pnas.org www.pnas.org
    Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer immunotherapy via synergistic co-activation of myeloid receptors CD40 and Dectin-1
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    Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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    Intratumor microbiome-derived butyrate promotes lung cancer metastasis
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  34. Mar 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
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  36. Feb 2024
  37. aacrjournals.org aacrjournals.org
    Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
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    aacrjournals.org/cancerimmunolres/article/12/2/247/733768/Engagement-of-CD99-Activates-Distinct-Programs-in
  38. www.biorxiv.org www.biorxiv.org
    Loss of TIM4-Dependent Efferocytosis in Kupffer Cells Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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    sciencedirect.com/science/article/pii/S1550413123004126
  40. Jan 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dietary folate and cofactors accelerate age-dependent p16 epimutation to promote intestinal tumorigenesis
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PPARγ Deacetylation Suppresses Aging-Associated Atherosclerosis and Hypercholesterolemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9917767/
  43. www.biorxiv.org www.biorxiv.org
    AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
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  44. Dec 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
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    A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
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    ncbi.nlm.nih.gov/pmc/articles/PMC10692727/
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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  49. www.science.org www.science.org
    Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1
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  50. 52.53.155.43 52.53.155.43
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  51. Nov 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    Host-microbiome interactions in distinct subsets of preterm labor and birth
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    Fibroblast Growth Factor 23 Neutralizing Antibody Ameliorates Abnormal Renal Phosphate Handling in Sickle Cell Disease Mice
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  56. www.nature.com www.nature.com
    Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
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    CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions
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  59. Oct 2023
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    HDL inhibits pancreatic acinar cell NLRP3 inflammasome activation and protect against acinar cell pyroptosis in acute pancreatitis
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    Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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  63. Sep 2023
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    Effects of butyl benzyl phthalate exposure during pregnancy and lactation on the post-involution mammary gland
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    Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
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  66. Aug 2023
  67. 52.53.155.43 52.53.155.43
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    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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  71. Jun 2023
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    Sublethal necroptosis signaling promotes inflammation and liver cancer
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    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
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  76. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors
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  79. Apr 2023
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    Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells
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    Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers
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    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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  84. Feb 2023
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  86. Jan 2023
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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  90. Dec 2022
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    GABA regulates IL-1β production in macrophages
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    Mouse placenta fetal macrophages arise from endothelial cells outside the placenta
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  93. Nov 2022
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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  96. Sep 2022
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    Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice
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  98. Aug 2022
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    Human colon cancer-derived Clostridioides difficile strains drive colonic tumorigenesis in mice
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  100. Jun 2022
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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  103. May 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer
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      DOI: 10.1016/j.ebiom.2022.104050

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  105. Apr 2022
  106. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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      DOI: 10.1016/j.molcel.2022.03.027

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  107. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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    sciencedirect.com/science/article/pii/S1074761322001315
  108. Mar 2022
  109. www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu
    Spatial CRISPR genomics identifies regulators of the tumor microenvironment
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      DOI: 10.1016/j.cell.2022.02.015

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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A murine model of cerebral cavernous malformations with acute hemorrhage
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  111. www.nature.com www.nature.com
    Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
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  112. Feb 2022
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    A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis
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  114. Nov 2021
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    ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
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  116. www.sciencedirect.com www.sciencedirect.com
    TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
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  117. Aug 2021
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    Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice
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  119. May 2021
  120. www.nature.com www.nature.com
    Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
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  121. Apr 2021
  122. www.sciencedirect.com www.sciencedirect.com
    Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo
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    The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis
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  124. Mar 2021
  125. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  126. Jan 2021
  127. www.sciencedirect.com www.sciencedirect.com
    Interleukin-24 protects against liver injury in mouse models
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      DOI: 10.1016/j.ebiom.2021.103213

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  128. Dec 2020
  129. www.sciencedirect.com www.sciencedirect.com
    Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution
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    sciencedirect.com/science/article/pii/S2211124720314613
  130. Sep 2020
  131. www.sciencedirect.com www.sciencedirect.com
    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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      DOI: 10.1016/j.ccell.2020.01.011

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