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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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  3. Jul 2024
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    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
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    cell.com/cell-reports-medicine/abstract/S2666-3791(24)00362-8
  5. Jun 2024
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    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
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    The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity
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      DOI: 10.1158/2326-6066.CIR-23-1078

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148535/
  8. May 2024
  9. 52.53.155.43 52.53.155.43
    cir-23-1078-html.html
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    Development of nitroalkene-based inhibitors to target STING-dependent inflammation
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    sciencedirect.com/science/article/pii/S2213231724001800
  11. Apr 2024
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    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2666379124001976
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    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    sciencedirect.com/science/article/pii/S2211124724004169
  15. Mar 2024
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    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
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  17. Jan 2024
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
  19. Nov 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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    1. scibot 30 Nov 2023
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      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  21. Aug 2023
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    4-Octyl itaconate restricts STING activation by blocking its palmitoylation
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  23. Jul 2023
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    Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy
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      DOI: 10.1016/j.celrep.2023.112852

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  25. Jun 2023
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
    1
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    sciencedirect.com/science/article/pii/S1535610823001733
  27. Apr 2023
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    Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING
    1
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    sciencedirect.com/science/article/pii/S2211124723004539
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    Lithium ameliorates Niemann-Pick C1 disease phenotypes by impeding STING/SREBP2 activation
    1
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      DOI: 10.1016/j.isci.2023.106613

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    sciencedirect.com/science/article/pii/S2589004223006909
  30. Mar 2023
  31. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
    1
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    europepmc.org/article/med/36952341
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    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
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      DOI: 10.1016/j.celrep.2023.112306

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    sciencedirect.com/science/article/pii/S2211124723003170
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    NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking
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    sciencedirect.com/science/article/pii/S2211124723001961
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    4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING
    1
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    sciencedirect.com/science/article/pii/S2211124723001560
  35. Dec 2022
  36. www.sciencedirect.com www.sciencedirect.com
    The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER
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    sciencedirect.com/science/article/pii/S2211124722017648
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    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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    sciencedirect.com/science/article/pii/S2211124722016527
  38. Sep 2022
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    ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
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    sciencedirect.com/science/article/pii/S1074761322003995
  40. Jun 2022
  41. rupress.org rupress.org
    ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1083/jcb.202106046

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    rupress.org/jcb/article/221/7/e202106046/213259/ER-lysosome-lipid-transfer-protein-VPS13C-PARK23
  42. May 2022
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    STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
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    sciencedirect.com/science/article/pii/S2211124722006118
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    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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    1. scibot 11 May 2022
      RRID:AB_279983

      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  45. Jan 2022
  46. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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    1. scibot 05 Jan 2022
      RRID:AB_2799831

      DOI: 10.1016/j.cmet.2021.12.007

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    sciencedirect.com/science/article/pii/S1550413121006264
  47. Jul 2021
  48. www.nature.com www.nature.com
    Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
    1
    1. scibot 31 Jul 2021
      72971

      DOI: 10.1038/s41586-021-03762-2

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    nature.com/articles/s41586-021-03762-2
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function
    1
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      DOI: 10.1016/j.molcel.2020.12.024

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    sciencedirect.com/science/article/pii/S109727652030945X
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    LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
    1
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      DOI: 10.1016/j.molcel.2020.10.021

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    sciencedirect.com/science/article/pii/S1097276520307280
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
    1
    1. scibot 22 Apr 2021
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2020.11.004

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    sciencedirect.com/science/article/pii/S1535610820305961
  54. www.sciencedirect.com www.sciencedirect.com
    Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
    1
    1. scibot 17 Apr 2021
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2020.05.020

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    sciencedirect.com/science/article/pii/S1535610820302701
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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    1. scibot 23 Sep 2020
      RRID:AB_2799831

      DOI: 10.1016/j.celrep.2020.03.056

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    sciencedirect.com/science/article/pii/S2211124720303703
  57. www.sciencedirect.com www.sciencedirect.com
    Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
    1
    1. scibot 16 Sep 2020
      RRID:AB_2799831

      DOI: 10.1016/j.immuni.2020.03.016

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    sciencedirect.com/science/article/pii/S1074761320301291
  58. www.sciencedirect.com www.sciencedirect.com
    mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury
    1
    1. scibot 06 Sep 2020
      RRID:AB_2799831

      DOI: 10.1016/j.immuni.2020.02.002

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    sciencedirect.com/science/article/pii/S107476132030073X
  59. www.nature.com www.nature.com
    C9orf72 in myeloid cells suppresses STING-induced inflammation
    1
    1. scibot 03 Sep 2020
      phospo-STING Ser 365

      DOI: 10.1038/s41586-020-2625-x

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      Curator comments: Phospho-STING (Ser365) (D8F4W) Rabbit mAb antibody Cell Signaling Technology Cat# 72971

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    nature.com/articles/s41586-020-2625-x
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2799831

      DOI: 10.1016/j.ccell.2019.11.003

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    sciencedirect.com/science/article/pii/S1535610819305239