Hypothesis

32 Matching Annotations

Last 7 days
www.science.org www.science.org

A mitochondrial ROS–dependent antiviral response promotes β cell resilience and is diminished in donors with type 1 diabetes

1
1. scibot 28 May 2026
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1126/scitranslmed.adx7770
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

science.org/doi/10.1126/scitranslmed.adx7770
May 2026
www.sciencedirect.com www.sciencedirect.com

Salmonella effector SteE reprograms the macrophage regulatory network to drive specific hyperactivation of STAT3 target genes

1
1. scibot 09 May 2026
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.molcel.2026.04.012
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276526002662
Mar 2026
www.sciencedirect.com www.sciencedirect.com

4-octyl itaconate inhibits cytokine-mediated inflammation via alkylation of TYK2 and JAK1

1
1. scibot 31 Mar 2026
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2026.117179
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726002573
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Dual roles of USP39 in stabilizing PB2 and orchestrating ribonucleoprotein assembly drive H5 influenza virus replication and pathogenicity

1
1. scibot 19 Feb 2026
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2026.117002
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472600080X
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis

1
1. scibot 23 Jun 2025
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1186/s13024-025-00864-7
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12181884/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Phase transition of WTAP regulates m6A modification of interferon-stimulated genes

1
1. scibot 31 May 2025
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.7554/eLife.100601
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12113268/
www.sciencedirect.com www.sciencedirect.com

Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.ebiom.2025.105734
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396425001781
Feb 2025
52.53.155.43 52.53.155.43

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis

1
1. scibot 06 Feb 2025
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1101/2024.09.09.611621
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

52.53.155.43/ccdd8f2b9b0076ccdaf42c273b248e5adbb5da1d/2024.09.09.611621v1.full-html.html
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Regulation of human interferon signaling by transposon exonization

1
1. scibot 14 Dec 2024
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.cell.2024.11.016
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424013333
Sep 2024
www.sciencedirect.com www.sciencedirect.com

CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway

1
1. scibot 26 Sep 2024
  
  in Public
  
  AB_2800123
  
  DOI: 10.1016/j.xgen.2024.100659
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666979X24002702
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis

1
1. scibot 10 Apr 2024
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.isci.2024.109533
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11000115/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon

2
1. scibot 06 Mar 2024
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.devcel.2024.02.005
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
2. scibot 06 Mar 2024
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.devcel.2024.02.005
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580724000765
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.chom.2023.08.003
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1931312823003281
www.sciencedirect.com www.sciencedirect.com

Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection

1
1. scibot 08 Sep 2023
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.devcel.2023.08.013
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580723004094
Aug 2023
www.sciencedirect.com www.sciencedirect.com

Hedgehog receptors exert immune-surveillance roles in the epidermis across species

1
1. scibot 03 Aug 2023
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2023.112929
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723009403
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL

1
1. scibot 18 Nov 2022
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.7554/eLife.81606
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9651953/
Aug 2022
www.sciencedirect.com www.sciencedirect.com

The redox cycling of STAT2 maintains innate immune homeostasis

1
1. scibot 17 Aug 2022
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2022.111215
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722010324
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

1
1. scibot 27 Jul 2022
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.15252/embj.2021109217
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9289529/
Mar 2022
www.sciencedirect.com www.sciencedirect.com

Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling

1
1. scibot 02 Mar 2022
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.isci.2022.103833
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222001031
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling

1
1. scibot 23 Feb 2022
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.chom.2022.01.014
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1931312822000506
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death

1
1. scibot 07 Aug 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.cell.2021.07.026
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867421008850
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2019.10.038
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112471931352X
www.nature.com www.nature.com

IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1038/s41467-019-12318-y
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2800123
  
  Curator comments: Phospho-Stat2 (Tyr690) (D3P2P) Rabbit mAb antibody Cell Signaling Technology Cat# 88410
  
  What is this?
  
  RRID:AB_2800123 RRIDCUR:Unresolved RRIDCUR:SyntaxError
Visit annotations in context

Tags

RRIDCUR:Unresolved

RRIDCUR:SyntaxError

RRID:AB_2800123

Annotators

scibot

URL

nature.com/articles/s41467-019-12318-y
May 2021
www.sciencedirect.com www.sciencedirect.com

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

1
1. scibot 11 May 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.isci.2021.102477
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004221004454
Mar 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 13 Mar 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1111/bph.15357
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2800123

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15357
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Evasion of type-I interferon by SARS-CoV-2

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2020.108234
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123
Visit annotations in context

Tags

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720312237
Jan 2021
www.sciencedirect.com www.sciencedirect.com

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

1
1. scibot 22 Jan 2021
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2020.108628
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472031617X
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Evasion of type-I interferon by SARS-CoV-2

1
1. scibot 01 Oct 2020
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2020.108234
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2800123
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720312237
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2020.107633
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720305866
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.immuni.2020.07.006
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2800123
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2800123

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC7398039/
www.sciencedirect.com www.sciencedirect.com

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:AB_2800123
  
  DOI: 10.1016/j.celrep.2020.01.054
  
  Resource: (Cell Signaling Technology Cat# 88410, RRID:AB_2800123)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2800123
  
  What is this?
  
  RRID:AB_2800123 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2800123

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720300796