Hypothesis

31 Matching Annotations

Last 7 days
aacrjournals.org aacrjournals.org

Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy

1
1. scibot 23 Apr 2026
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1158/2159-8290.CD-25-0649
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

aacrjournals.org/cancerdiscovery/article/16/1/155/771238/Activation-of-T-Cell-Intrinsic-p53-by-Acetylation
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nerves Stimulate Cross-talk Between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression

1
1. scibot 17 Apr 2026
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1158/0008-5472.CAN-25-3092
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13080324/
Dec 2025
link.springer.com link.springer.com

Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer

1
1. scibot 11 Dec 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1186/s13058-025-02176-6
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

link.springer.com/article/10.1186/s13058-025-02176-6
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization

1
1. scibot 11 Oct 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1371/journal.ppat.1013563
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12510645/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches

1
1. scibot 27 Sep 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2025.09.001
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825003939
May 2025
www.sciencedirect.com www.sciencedirect.com

Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

1
1. scibot 29 May 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.immuni.2025.04.030
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761325001931
www.sciencedirect.com www.sciencedirect.com

Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception

1
1. scibot 16 May 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2025.04.003
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153561082500162X
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies

1
1. scibot 23 Mar 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1101/2025.02.28.640707
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11908201/
Feb 2025
www.cell.com www.cell.com

EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models

1
1. scibot 25 Feb 2025
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2025.01.013
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

cell.com/cancer-cell/abstract/S1535-6108(25)00031-5
Jul 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain

1
1. scibot 19 Jul 2024
  
  in Public
  
  AB_2800152
  
  DOI: 10.1002/pros.24766
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/pros.24766
www.cell.com www.cell.com

Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

1
1. scibot 18 Jul 2024
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2024.06.001
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB

1
1. scibot 26 Apr 2024
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.cell.2024.03.022
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424003131
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pyroptotic T cell-derived active IL-16 has a driving function in ovarian endometriosis development

1
1. scibot 03 Apr 2024
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.xcrm.2024.101476
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10983113/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer

1
1. scibot 03 Mar 2024
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.xcrm.2024.101397
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10897543/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Host-microbiome interactions in distinct subsets of preterm labor and birth

1
1. scibot 29 Nov 2023
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.isci.2023.108341
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223024185
Aug 2023
www.sciencedirect.com www.sciencedirect.com

A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

1
1. scibot 16 Aug 2023
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.xcrm.2023.101154
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123003075
Jun 2023
52.53.155.43 52.53.155.43

Macrophage-derived cathepsin S remodels the extracellular matrix to promote liver fibrogenesis

1
1. scibot 16 Jun 2023
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1053/j.gastro.2023.05.039
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

52.53.155.43/6547da8aa0b8d7e491fdd14880a12803f28db0ef/1-s2.0-S0016508523008120-main-html.html
Apr 2023
www.sciencedirect.com www.sciencedirect.com

AKT activity orchestrates marginal zone B cell development in mice and humans

1
1. scibot 15 Apr 2023
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.celrep.2023.112378
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723003893
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma

1
1. scibot 28 Jan 2023
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2022.12.004
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610822005906
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer

1
1. scibot 17 Dec 2022
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2022.11.016
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610822005633
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Defining HPV-specific B cell responses in head and neck cancer patients

1
1. scibot 21 Sep 2022
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1038/s41586-020-2931-3
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9462833/
www.sciencedirect.com www.sciencedirect.com

Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity

1
1. scibot 13 Sep 2022
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.xcrm.2022.100744
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379122002932
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers

1
1. scibot 31 Aug 2022
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.celrep.2022.111295
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722011159
Jan 2022
www.sciencedirect.com www.sciencedirect.com

TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures

1
1. scibot 12 Jan 2022
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.immuni.2021.12.007
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761321005434
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer

1
1. scibot 15 Oct 2021
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2021.09.010
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610821004992
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts

1
1. scibot 17 Aug 2021
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.celrep.2021.109422
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8362934/
May 2021
academic.oup.com academic.oup.com

Prostate-specific deletion of Cdh1 induces murine prostatic inflammation and bladder overactivity

1
1. scibot 10 May 2021
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1210/endocr/bqaa212
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

academic.oup.com/endo/article/162/1/bqaa212/5992231
www.sciencedirect.com www.sciencedirect.com

Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1053/j.gastro.2020.11.044
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S001650852035513X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.ccell.2021.02.003
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610821001057
www.sciencedirect.com www.sciencedirect.com

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1016/j.molcel.2021.03.043
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2800152
Visit annotations in context

Tags

RRID:AB_2800152

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521002641
Dec 2020
journals.sagepub.com journals.sagepub.com

Cnp Promoter-Driven Sustained ERK1/2 Activation Increases B-Cell Activation and Suppresses Experimental Autoimmune Encephalomyelitis - Marisa A. Jeffries, Alison E. Obr, Kelly Urbanek, Sharyl L. Fyffe-Maricich, Teresa L. Wood, 2020

1
1. scibot 07 Dec 2020
  
  in Public
  
  RRID:AB_2800152
  
  DOI: 10.1177/1759091420971916
  
  Resource: (Cell Signaling Technology Cat# 90176, RRID:AB_2800152)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2800152
  
  What is this?
  
  RRID:AB_2800152 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2800152

RRIDCUR:Validated

Annotators

scibot

URL

journals.sagepub.com/doi/full/10.1177/1759091420971916