51 Matching Annotations
  1. Last 7 days
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    Organotypic vascularization improves maturation of human stem cell-derived islets and restores normoglycemia in diabetic mice
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    sciencedirect.com/science/article/pii/S193459092600353X
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A mitochondrial ROS–dependent antiviral response promotes β cell resilience and is diminished in donors with type 1 diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13488389/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual phenotype in a patient with adult-onset hyperinsulinism and diabetes caused by an activating MAFA variant
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    pmc.ncbi.nlm.nih.gov/articles/PMC13457921/
  6. Jul 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Importance of antibody validation in detecting cell cycle regulatory protein p16 INK4A by immunohistochemistry on pancreas tissue
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    pmc.ncbi.nlm.nih.gov/articles/PMC13390536/
  8. May 2026
  9. www.science.org www.science.org
    A mitochondrial ROS–dependent antiviral response promotes β cell resilience and is diminished in donors with type 1 diabetes
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    science.org/doi/10.1126/scitranslmed.adx7770
  10. Feb 2026
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    Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles
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    sciencedirect.com/science/article/pii/S2666379126000510
  12. Dec 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCL22-expressing Stem Cell–derived Islet Grafts Recruit Regulatory T Cells in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12711295/
  14. Nov 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pig Taste Cell-Derived Organoids Synthesize Insulin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12641528/
  16. Jun 2025
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    Offspring metabolic programming via the maternal diet increases susceptibility to metabolic dysregulation
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    sciencedirect.com/science/article/pii/S2352396425002610
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXM1 cooperates with ERα to regulate functional β-cell mass
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145799/
  19. May 2025
  20. 52.53.155.43 52.53.155.43
    bqaf082-html.html
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    Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
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    sciencedirect.com/science/article/pii/S2352396425001781
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    Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling
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    sciencedirect.com/science/article/pii/S2211124725004188
  24. Apr 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β-Cell Dedifferentiation in HOMA-βlow and HOMA-βhigh Subjects
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    pmc.ncbi.nlm.nih.gov/articles/PMC12012814/
  26. Feb 2025
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    Bioengineering of a human iPSC-derived vascularized endocrine pancreas for type 1 diabetes
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    sciencedirect.com/science/article/pii/S2666379125000114
  28. Sep 2024
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    IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
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    sciencedirect.com/science/article/pii/S2589004224019928
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    Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation
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    sciencedirect.com/science/article/pii/S2666166724004623
  31. Jul 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impaired islet function and normal exocrine enzyme secretion occur with low inter-regional variation in type 1 diabetes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11251461/
  33. Jan 2024
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    Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner
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    sciencedirect.com/science/article/pii/S1534580723006913
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    SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788290/
  36. 52.53.155.43 52.53.155.43
    Discordant effects of polyamine depletion by DENSpm and DFMO on β cell cytokine stress and diabetes outcomes in mice
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  37. Dec 2023
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    Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes
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    sciencedirect.com/science/article/pii/S1550413123004436
  39. Nov 2023
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    Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes
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    sciencedirect.com/science/article/pii/S266637912300438X
  41. Jul 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inferring regulators of cell identity in the human adult pancreas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10331937/
  43. May 2023
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    Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure
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    sciencedirect.com/science/article/pii/S2666379123001659
  45. Apr 2023
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  47. Mar 2023
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    Protocol to generate human pluripotent stem cell-derived pancreatic β cells through methionine and zinc deprivation
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    sciencedirect.com/science/article/pii/S2666166723001417
  49. Dec 2022
  50. www.sciencedirect.com www.sciencedirect.com
    A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
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    sciencedirect.com/science/article/pii/S2352396422005618
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    Glycemic control releases regenerative potential of pancreatic beta cells blocked by severe hyperglycemia
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    sciencedirect.com/science/article/pii/S2211124722015972
  52. Nov 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
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    sciencedirect.com/science/article/pii/S2589004222016765
  54. academic.oup.com academic.oup.com
    Ageing Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Human
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac535/6705055
  55. Aug 2022
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    The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells
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    sciencedirect.com/science/article/pii/S2211124722009834
  57. Jul 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization
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    sciencedirect.com/science/article/pii/S2211124722009263
  59. Jun 2022
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    Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy
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    sciencedirect.com/science/article/pii/S2211124722008075
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    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
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    sciencedirect.com/science/article/pii/S2211124722008002
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9231709/
  63. Sep 2021
  64. link.springer.com link.springer.com
    Immunoregulated insulitis and slow-progressing type 1 diabetes after duodenopancreatectomy
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    link.springer.com/article/10.1007/s00125-021-05563-8
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    The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production
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    sciencedirect.com/science/article/pii/S1534580721006730
  66. Jul 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8289414/
  68. Jun 2021
  69. www.frontiersin.org www.frontiersin.org
    Offspring of Obese Dams Exhibit Sex-Differences in Pancreatic Heparan Sulfate Glycosaminoglycans and Islet Insulin Secretion
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    frontiersin.org/article/10.3389/fendo.2021.658439/full
  70. Feb 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
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    sciencedirect.com/science/article/pii/S1550413121000048
  72. Nov 2020
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19
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    ncbi.nlm.nih.gov/pmc/articles/PMC7664515/
  74. Jan 2020
  75. academic.oup.com academic.oup.com
    Cellular autophagy in α cells plays a role in the maintenance of islet architecture
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    academic.oup.com/jes/article/3/11/1979/5544516