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Tumor-to-dendritic cell reprogramming induces immunogenic lymphoid structures across cancers

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.immuni.2026.10.006
  
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sciencedirect.com/science/article/pii/S1074761326004322
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T cell cross-priming by PD-L1+ type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1×4-1BB bispecific antibody

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  DOI: 10.1016/j.immuni.2026.10.003
  
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sciencedirect.com/science/article/pii/S1074761326004280
Oct 2026
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Microglia with distinct origins and non-canonical phenotypes coexist within the border-like niche of the brain’s circumventricular organs

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1. scibot 01 Oct 2026
  
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  DOI: 10.1016/j.immuni.2026.09.002
  
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sciencedirect.com/science/article/pii/S1074761326003778
Sep 2026
dx.doi.org dx.doi.org

TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

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1. scibot 12 Sep 2026
  
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  DOI: 10.1084/jem.20252080
  
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dx.doi.org/10.1084/jem.20252080
Aug 2026
onlinelibrary.wiley.com onlinelibrary.wiley.com

Impact of Chronic Infection-Induced Inflammation on TREG Cell Homeostasis

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1. scibot 21 Aug 2026
  
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  DOI: 10.1002/eji.70265
  
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  DOI: 10.1002/eji.70265
  
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onlinelibrary.wiley.com/doi/10.1002/eji.70265
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Improving Anti–CTLA-4 Therapies through Peptide Masking and Fragment Crystallizable Non-fucosylation: Preclinical Characterization of Three Novel Antibodies

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1. scibot 07 Aug 2026
  
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  DOI: 10.1158/1078-0432.CCR-25-1230
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13367003/
Jul 2026
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B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

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1. scibot 05 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.003
  
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sciencedirect.com/science/article/pii/S1074761326002542
Jun 2026
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Stem-like precursors of exhausted Th cells upheld by a Tox-Myb-Eomes transcriptional hierarchy propagate Th cell responses in chronic infection

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1. scibot 26 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.06.001
  
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sciencedirect.com/science/article/pii/S1074761326002311
May 2026
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Intratumoral virus-like particles containing a TLR9-agonist combined with systemic αPD-1 activate tumor-specific CD8+ T cells

1
1. scibot 05 May 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0175
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13133427/
Apr 2026
54.241.53.176 54.241.53.176

2026.04.10.717764v1.full-html.html

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1. scibot 24 Apr 2026
  
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  DOI: 10.64898/2026.04.10.717764
  
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54.241.53.176/8e933d72b8683e9de5363e41f7d479996053fe44/2026.04.10.717764v1.full-html.html
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Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.ccell.2026.03.020
  
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sciencedirect.com/science/article/pii/S1535610826001741
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IFNγ-induced PD-L1+MHC II+ macrophages and Tim-3+ tumor-reactive CD8+ T cells predict a response to anti-PD-1 therapy in tumor-bearing mice

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-24-0835
  
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aacrjournals.org/cancerimmunolres/article/13/12/2004/768334/IFN-Induced-PD-L1-MHCII-Macrophages-and-Tim-3
54.241.53.176 54.241.53.176

Age-dependent tumor-immune interactions underlie immunotherapy response in pediatric cancer

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1. scibot 09 Apr 2026
  
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  DOI: 10.1101/2025.07.16.663652
  
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54.241.53.176/768db83f320dea5b389687f4152c3097d0ac27c7/2025.07.16.663652.full-html.html
Mar 2026
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Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity

1
1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.02.013
  
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sciencedirect.com/science/article/pii/S153561082600111X
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HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung

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1. scibot 10 Mar 2026
  
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  RRID:AB_2813886
  
  DOI: 10.1016/j.immuni.2026.01.023
  
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sciencedirect.com/science/article/pii/S1074761326000452
Feb 2026
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CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.ccell.2026.01.006
  
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sciencedirect.com/science/article/pii/S1535610826000450
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Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition

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1. scibot 03 Feb 2026
  
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  RRID:AB_2813886
  
  DOI: 10.1016/j.immuni.2026.01.016
  
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sciencedirect.com/science/article/pii/S1074761326000385
Jan 2026
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Myelin antigen capture in the CNS by B cells expressing EBV latent membrane protein 1 leads to demyelinating lesion formation

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1. scibot 15 Jan 2026
  
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  RRID:AB_2813886
  
  DOI: 10.1016/j.cell.2025.12.031
  
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sciencedirect.com/science/article/pii/S0092867425014801
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DF6215, an α-optimized IL-2-Fc fusion, expands immune effectors and drives robust preclinical anti-tumor activity

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102518
  
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sciencedirect.com/science/article/pii/S2666379125005919
Dec 2025
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IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis

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1. scibot 23 Dec 2025
  
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  DOI: 10.1073/pnas.2519141122
  
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  DOI: 10.1073/pnas.2519141122
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12718373/
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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

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1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.020
  
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sciencedirect.com:5037/science/article/pii/S1074761325005229
Oct 2025
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Quercetin-derived microbial metabolite DOPAC potentiates CD8+ T cell anti-tumor immunity via NRF2-mediated mitophagy

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.cmet.2025.09.010
  
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sciencedirect.com/science/article/pii/S155041312500395X
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TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.011
  
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sciencedirect.com/science/article/pii/S1535610825004039
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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1. scibot 04 Oct 2025
  
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  RRID:AB_2813886
  
  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
Sep 2025
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Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.08.027
  
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sciencedirect.com/science/article/pii/S0092867425009821
Aug 2025
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Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells

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1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.007
  
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sciencedirect.com/science/article/pii/S1074761325003164
Jul 2025
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Naturalized immune responses are stable over years in a colony of laboratory mice with wild-derived microbiota

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.07.004
  
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sciencedirect.com/science/article/pii/S1074761325003139
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Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.021
  
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sciencedirect.com/science/article/pii/S1535610825002715
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Activity-attenuated serum albumin-fused interleukin-33 suppresses experimental autoimmune encephalomyelitis

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102231
  
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sciencedirect.com/science/article/pii/S2666379125003040
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

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1. scibot 02 Jul 2025
  
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  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Jun 2025
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Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102204
  
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sciencedirect.com/science/article/pii/S2666379125002770
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
May 2025
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IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in mouse colon cancer

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1. scibot 29 May 2025
  
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  RRID:AB_2813886
  
  DOI: 10.1016/j.isci.2025.112639
  
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sciencedirect.com/science/article/pii/S2589004225009009
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Dietary targeting of TRPM8 rewires macrophage immunometabolism reducing colitis severity

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1. scibot 19 May 2025
  
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  RRID:AB_2813886
  
  DOI: 10.1038/s41419-025-07553-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12032354/
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Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology

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Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii

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Mar 2025
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Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME

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Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy

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EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function

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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes

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Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition

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Baf155 controls hematopoietic differentiation and regeneration through chromatin priming

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Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

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The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

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Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs

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Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

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Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade

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Characterization of immune populations in the tumor microenvironment of diffuse midline glioma orthotopic mouse models by flow cytometry

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Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics

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Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells

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Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice

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cd-22-1301-html.html

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Nov 2023
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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

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Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC

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Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis

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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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Aug 2022
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Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis

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Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

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Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

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Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor

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Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq

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A Booster Dose Enhances Immunogenicity of the COVID-19 Vaccine Candidate ChAdOx1 nCoV-19 in Aged Mice

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