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Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells

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  DOI: 10.1016/j.cell.2026.03.046
  
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sciencedirect.com/science/article/pii/S009286742600382X
Apr 2026
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m5C-Modified tRF3b-CysGCA-23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

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1. scibot 02 Apr 2026
  
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  DOI: 10.1002/advs.202522294
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522294
Mar 2026
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Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts

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  DOI: 10.1016/j.cmet.2026.02.008
  
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sciencedirect.com/science/article/pii/S1550413126000513
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BPS Publications

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  DOI: 10.1111/bph.70330
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70330
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Sec61β maintains cytoplasmic proteostasis via ARIH1-mediated translational repression upon ER stress

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  DOI: 10.1038/s44319-026-00690-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12936171/
Feb 2026
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1-s2.0-S2589004226002919-main-html.html

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pmc.ncbi.nlm.nih.gov/articles/PMC12936848/
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Porcine IRF2 suppresses the cGAS-STING-mediated antiviral IFN signaling by competing IRF3 for binding to the IFN promoter

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  DOI: 10.1016/j.celrep.2026.116962
  
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sciencedirect.com/science/article/pii/S2211124726000409
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Supplemental_Material.pdf

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  DOI: 10.1101/gr.280528.125
  
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pmc.ncbi.nlm.nih.gov/articles/instance/12863058/bin/Supplemental_Material.pdf
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Transcriptomic landscape of transposable elements reveals LTR7-PLAAT4 as a potential oncogene and therapeutic target in pancreatic adenocarcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12863058/
Jan 2026
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METTL3/CD98-mediated glutamate efflux in CAFs drives CD8+ T cell exhaustion and impedes neoadjuvant immunochemotherapy

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  DOI: 10.1016/j.celrep.2026.116933
  
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sciencedirect.com/science/article/pii/S2211124726000112
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A positive feedback loop between FGR and p65 sustains satellite glial cell activation and chronic neuropathic pain

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  DOI: 10.1016/j.celrep.2025.116899
  
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Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer

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  DOI: 10.1016/j.xcrm.2025.102534
  
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sciencedirect.com/science/article/pii/S266637912500607X
Nov 2025
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Schlafen 12 Modulation and Targeting in Acute Myeloid Leukemia

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1. scibot 20 Nov 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0283
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12620962/
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Identification of ATG7 as a protein ATG8ylation substrate

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  DOI: 10.1016/j.celrep.2025.116485
  
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sciencedirect.com/science/article/pii/S2211124725012562
Oct 2025
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Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116487
  
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sciencedirect.com/science/article/pii/S2211124725012586
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DEC1 promotes breast cancer bone metastasis through transcriptional activation of CXCR4

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  DOI: 10.7555/JBR.39.20250031
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12481698/
Sep 2025
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Molecular basis for shifted receptor recognition by an encephalitic arbovirus

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  DOI: 10.1016/j.cell.2025.03.029
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406711/
Aug 2025
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The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi

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  DOI: 10.1016/j.devcel.2025.07.010
  
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sciencedirect.com/science/article/pii/S1534580725004484
Jul 2025
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RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

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  DOI: 10.1038/s41388-025-03502-0
  
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nature.com/articles/s41388-025-03502-0
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The planar cell polarity (PCP) protein Fat 1 in Sertoli cell function

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  DOI: 10.1210/endocr/bqae041
  
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dx.doi.org/10.1210/endocr/bqae041
Jun 2025
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The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible

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GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer

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  DOI: 10.1016/j.celrep.2025.115774
  
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Apr 2025
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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

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sciencedirect.com/science/article/pii/S2211124725003663
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Molecular basis for shifted receptor recognition by an encephalitic arbovirus

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PDF-html.html

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  DOI: 10.1158/2326-6066.cir-24-0834
  
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52.53.155.43/b8eb1cd1446295bdd52d11650093cdf439d34361/PDF-html.html
Mar 2025
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AGO2 mediates immunotherapy failure via suppressing tumor IFN-gamma response-dependent CD8+ T cell immunity

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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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Feb 2025
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A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation

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Jan 2025
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DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma

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  DOI: 10.1016/j.devcel.2024.12.035
  
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Dec 2024
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Aryl Hydrocarbon Receptor Alleviates Hepatic Fibrosis by Inducing Hepatic Stellate Cell Ferroptosis

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  DOI: 10.1111/jcmm.70278
  
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onlinelibrary.wiley.com/doi/10.1111/jcmm.70278
Nov 2024
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can-24-1817-html.html

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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Sep 2024
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ZIKV Induces P62-Mediated Autophagic Degradation of TRAF6 through TRAF6-NS1 Interaction

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  DOI: 10.1016/j.isci.2024.110757
  
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sciencedirect.com/science/article/pii/S2589004224019825
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CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway

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  DOI: 10.1016/j.isci.2024.110832
  
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PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders

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  DOI: 10.1016/j.cmet.2024.08.009
  
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sciencedirect.com/science/article/pii/S1550413124003619
Jul 2024
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Genome-scale exon perturbation screens uncover exons critical for cell fitness

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Jun 2024
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Circ_0007432 promotes non-small cell lung cancer progression and macrophage M2 polarization through SRSF1/KLF12 axis

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May 2024
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Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation

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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

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Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects

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Intratumor microbiome-derived butyrate promotes lung cancer metastasis

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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

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Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves

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Renal macrophages monitor and remove particles from urine to prevent tubule obstruction

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Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation

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WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation

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May 2023
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Exercise improves homeostasis of the intestinal epithelium by activation of APJ-AMPK signaling

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Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex

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The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html

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Apr 2023
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Hepatitis C virus hypervariable region 1 antibodies interrupt E2-SR-B1 interaction to suppress viral infection

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Mar 2023
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Epithelial cells activate fibroblasts to promote esophageal cancer development

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TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification

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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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Dec 2021
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Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

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Oct 2021
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Thy1-positive spermatogonia suppress the proliferation of spermatogonial stem cells by Extracellular vesicles in vitro

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Aug 2021
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Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

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FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue

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SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain

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YAP regulates cell size and growth dynamics via non-cell autonomous mediators

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