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Microcephaly-causative ASPM mutations disrupt mitotic spindle orientation and timely specification of human outer radial glia cells

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1. scibot 05 Nov 2026
  
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  RRID:AB_2827749
  
  DOI: 10.1016/j.devcel.2026.10.007
  
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sciencedirect.com/science/article/pii/S153458072600393X
Sep 2026
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Directing GABAergic neuronal identity from human iPSCs through developmental patterning

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1. scibot 29 Sep 2026
  
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  DOI: 10.1016/j.stemcr.2026.103086
  
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sciencedirect.com/science/article/pii/S2213671126002973
Aug 2026
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AAV-DJ enables efficient, function-preserving neuronal transduction for circuit interrogation in human cortical and thalamic organoids

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1. scibot 15 Aug 2026
  
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  DOI: 10.1016/j.crmeth.2026.101546
  
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sciencedirect.com/science/article/pii/S266723752600247X
Mar 2026
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Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration

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1. scibot 18 Mar 2026
  
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  RRID:AB_2827749
  
  DOI: 10.1016/j.stem.2025.12.019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12973372/
Aug 2025
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A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro

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1. scibot 28 Aug 2025
  
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  DOI: 10.1016/j.devcel.2025.08.001
  
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sciencedirect.com/science/article/pii/S1534580725005015
Jul 2025
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Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects

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1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.neuron.2025.06.017
  
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sciencedirect.com/science/article/pii/S0896627325004751
Dec 2024
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Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models

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1. scibot 28 Dec 2024
  
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  DOI: 10.1101/2024.12.03.626438
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11642846/
Oct 2023
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Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy

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1. scibot 13 Oct 2023
  
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  RRID:AB_2827749
  
  DOI: 10.1016/j.stem.2023.08.013
  
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  Curator: @jmitrevska
  
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sciencedirect.com/science/article/pii/S1934590923002965
Oct 2022
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Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state

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1. scibot 18 Oct 2022
  
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  DOI: 10.1038/s41598-022-22405-8
  
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nature.com/articles/s41598-022-22405-8
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Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms

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1. scibot 04 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105140
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9523398/
May 2022
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Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells

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1. scibot 05 May 2022
  
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  AB_2827749
  
  DOI: 10.1523/ENEURO.0442-21.2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9047030/
Oct 2021
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Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy

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1. scibot 06 Oct 2021
  
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  DOI: 10.1016/j.isci.2021.103140
  
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sciencedirect.com/science/article/pii/S2589004221011081
May 2021
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A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.06.004
  
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sciencedirect.com/science/article/pii/S193459092030271X
Apr 2021
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Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma

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1. scibot 11 Apr 2021
  
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  RRID:AB_2827749
  
  DOI: 10.1016/j.stem.2021.02.003
  
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sciencedirect.com/science/article/pii/S1934590921000539