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Dcr1 senses R-loops for RNAPII termination at sites of replication stress and repair pathway choice

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.10.004
  
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sciencedirect.com/science/article/pii/S1097276525008202
Oct 2025
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BET family BRD3 initiates DSB-induced chromatin remodeling with TIP60 to promote R-loop-mediated HR

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116461
  
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sciencedirect.com/science/article/pii/S221112472501232X
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The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids

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1. scibot 22 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116438
  
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sciencedirect.com/science/article/pii/S2211124725012094
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Targeting the UFL1-PARP1 axis amplifies anti-tumor immunity

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116433
  
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sciencedirect.com/science/article/pii/S2211124725012045
Apr 2025
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ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.04.004
  
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sciencedirect.com/science/article/pii/S1097276525003077
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1. scibot 13 Apr 2025
  
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  AB_2861387
  
  DOI: 10.1016/j.isci.2025.112408
  
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52.53.155.43/1d7f3a53d05f85c55a541cebaae421bfbc1ec25f/PDF-html.html
Feb 2025
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SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.molcel.2025.01.008
  
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sciencedirect.com/science/article/pii/S1097276525000425
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional conservation and divergence of arabidopsis VENOSA4 and human SAMHD1 in DNA repair

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1. scibot 25 Jan 2025
  
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  DOI: 10.1016/j.heliyon.2024.e41019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11720913/
Dec 2024
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DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.029
  
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sciencedirect.com/science/article/pii/S1097276524009547
Oct 2024
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Long noncoding RNA TUG1 regulates smooth muscle cell differentiation via KLF4-myocardin axis

1
1. scibot 02 Oct 2024
  
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  DOI: 10.1152/ajpcell.00275.2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10635660/
Sep 2024
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

1
1. scibot 10 Sep 2024
  
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  AB_2861387
  
  DOI: 10.1016/j.cell.2024.08.014
  
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sciencedirect.com/science/article/pii/S009286742400905X
May 2024
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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

1
1. scibot 21 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114214
  
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sciencedirect.com/science/article/pii/S2211124724005424
Jan 2024
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ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1

1
1. scibot 19 Jan 2024
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.devcel.2023.12.018
  
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sciencedirect.com/science/article/pii/S1534580723006986
Oct 2023
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The splicing factor DHX38 enables retinal development through safeguarding genome integrity

1
1. scibot 14 Oct 2023
  
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  AB_2861387
  
  DOI: 10.1016/j.isci.2023.108103
  
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sciencedirect.com/science/article/pii/S2589004223021806
Aug 2023
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Small molecule targeting of transcription-replication conflict for selective chemotherapy

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1. scibot 03 Aug 2023
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.chembiol.2023.07.001
  
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sciencedirect.com/science/article/pii/S2451945623002210
Jul 2023
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Inhibition of nucleolar transcription by oxaliplatin involves ATM/ATR kinase signaling

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.chembiol.2023.06.010
  
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sciencedirect.com/science/article/abs/pii/S2451945623001885
Jun 2023
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Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability

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1. scibot 09 Jun 2023
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.molcel.2023.05.015
  
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sciencedirect.com/science/article/pii/S1097276523003714
May 2023
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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

1
1. scibot 20 May 2023
  
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  RRID:AB_2861387
  
  DOI: 10.1016/j.cell.2023.04.035
  
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sciencedirect.com/science/article/pii/S0092867423004695
Mar 2023
academic.oup.com academic.oup.com

ATXN3 controls DNA replication and transcription by regulating chromatin structure

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1. scibot 29 Mar 2023
  
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  RRID:AB_2861387
  
  DOI: 10.1093/nar/gkad212
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad212/7086677
Nov 2022
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Metabolic regulation by p53 prevents R-loop-associated genomic instability

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1. scibot 03 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111568
  
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sciencedirect.com/science/article/pii/S2211124722014292
Oct 2022
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DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111526
  
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sciencedirect.com/science/article/pii/S2211124722013821
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TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch

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1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.026
  
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sciencedirect.com/science/article/pii/S1097276522009364
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p300/CBP sustains Polycomb silencing by non-enzymatic functions

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1. scibot 07 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.005
  
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sciencedirect.com/science/article/pii/S1097276522008942
Jul 2022
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Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111067
  
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sciencedirect.com/science/article/pii/S2211124722008658
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

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1. scibot 17 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104404
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9194172/
May 2022
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Chl1 coordinates with H3K9 methyltransferase Clr4 to reduce the accumulation of RNA-DNA hybrids and maintain genome stability

1
1. scibot 13 May 2022
  
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  DOI: 10.1016/j.isci.2022.104313
  
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sciencedirect.com/science/article/pii/S2589004222005843
Mar 2022
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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments

1
1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110411
  
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sciencedirect.com/science/article/pii/S2211124722001358
Feb 2022
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RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair

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1. scibot 02 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110335
  
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sciencedirect.com/science/article/pii/S2211124722000511
Mar 2021
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MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

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1. scibot 01 Mar 2021
  
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  DOI: 10.1016/j.ccell.2020.12.010
  
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sciencedirect.com/science/article/pii/S1535610820306589
Jan 2021
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DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

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1. scibot 05 Jan 2021
  
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  Anti-DNA-RNA Hybrid Antibody, clone S9.6
  
  DOI: 10.1016/j.celrep.2020.108569
  
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  RRID:AB_2861387 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720315588
Sep 2020
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SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells

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1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108184
  
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  RRID:AB_2861387 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720311736