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Fibroblast MrgprX2/B2 signaling drives hypertrophic scar fibrosis

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1. scibot 29 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117616
  
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sciencedirect.com/science/article/pii/S2211124726006947
May 2026
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FOXA1-mediated CEPT1 deficiency in airway epithelium drives asthma via an ER stress-mitochondrial dysfunction axis

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1. scibot 27 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117368
  
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sciencedirect.com/science/article/pii/S2211124726004468
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Targeting the tumor microenvironment: reprogramming macrophages as a novel therapeutic strategy in FUOM-deficient glioblastoma

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1. scibot 22 May 2026
  
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  DOI: 10.1038/s41419-026-08701-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13187179/
Apr 2026
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Skin inflammation and itch response are independently regulated by distinct nociceptor subsets

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.020
  
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sciencedirect.com/science/article/pii/S1074761326001317
Mar 2026
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Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117185
  
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sciencedirect.com/science/article/pii/S2211124726002639
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Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.020
  
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sciencedirect.com/science/article/pii/S1534580726000857
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Gut microbiota immaturity with DL-endopeptidase deficiency links antibiotic use to preterm late-onset sepsis

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  DOI: 10.1016/j.chom.2026.02.004
  
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sciencedirect.com/science/article/pii/S1931312826000491
Feb 2026
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PFOS and PFOA exposure induces liver injury and sex-dependent immune effects in C57BL/6 mice

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1. scibot 07 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114693
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12865548/
Jan 2026
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A combined strategy of EGFR-MET bispecific antibody and HER3 ADC to overcome osimertinib resistance in NSCLC

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1. scibot 30 Jan 2026
  
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  DOI: 10.1007/s13402-025-01152-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12847129/
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IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3

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1. scibot 28 Jan 2026
  
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  DOI: 10.1038/s41467-025-67456-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12824406/
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Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116840
  
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sciencedirect.com/science/article/pii/S2211124725016122
Dec 2025
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Blood metabolic panels for identifying significant fibrosis and inflammation in patients with MASLD

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1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102522
  
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sciencedirect.com:5037/science/article/pii/S2666379125005956
Nov 2025
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Fluorinated prodrug-engineered nano-remodeler relieves tumor hypoxia for dual-enhanced ferroptosis-immunotherapy

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102427
  
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sciencedirect.com/science/article/pii/S2666379125005002
Aug 2025
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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.006
  
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sciencedirect.com/science/article/pii/S1535610825003101
Jul 2025
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Dual targeting of transferrin receptor and CD98hc enhances brain exposure of large molecules

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1. scibot 24 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116038
  
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sciencedirect.com/science/article/pii/S2211124725008095
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1-s2.0-S2589004225014282-main-html.html

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113167
  
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52.53.155.43/3ec5cc8f740b8a88e56e2eb5da6c6595637ab2d8/1-s2.0-S2589004225014282-main-html.html
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Antibody durability is influenced by interleukin-2 production by undifferentiated memory T helper cells and extensive B cell clonal expansion

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1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115934
  
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sciencedirect.com/science/article/pii/S2211124725007053
Jun 2025
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Comprehensive immune ageing reveals TREM2/TIM3 myeloid cells drive brain immune evasion

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.ebiom.2025.105833
  
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sciencedirect.com/science/article/pii/S2352396425002774
Apr 2025
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BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115493
  
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sciencedirect.com/science/article/pii/S2211124725002645
Mar 2025
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Enteric neuronal Piezo1 maintains mechanical and immunological homeostasis by sensing force

1
1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.02.031
  
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sciencedirect.com/science/article/pii/S0092867425002582
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Interferon-γ-stimulated antigen-presenting cancer-associated fibroblasts hinder neoadjuvant chemoimmunotherapy efficacy in lung cancer

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102017
  
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sciencedirect.com/science/article/pii/S2666379125000904
Feb 2025
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A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115321
  
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sciencedirect.com/science/article/pii/S2211124725000920
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C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia

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1. scibot 14 Feb 2025
  
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  DOI: 10.1158/2159-8290.CD-22-0411
  
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aacrjournals.org/cancerdiscovery/article/13/7/1720/727640/C-EBP-Confers-Dependence-to-Fatty-Acid-Anabolic
Nov 2024
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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.008
  
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sciencedirect.com/science/article/pii/S1535610824003969
Sep 2024
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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101718
  
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sciencedirect.com/science/article/pii/S2666379124004397
Jun 2024
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Fasting-mimicking diet remodels gut microbiota and suppresses colorectal cancer progression

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1. scibot 28 Jun 2024
  
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  DOI: 10.1038/s41522-024-00520-w
  
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link.springer.com/article/10.1038/s41522-024-00520-w
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Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.05.001
  
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sciencedirect.com/science/article/pii/S1550413124001773
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Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
Mar 2024
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Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer

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1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.022
  
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cell.com/cell/fulltext/S0092-8674(24)00224-1
Feb 2024
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Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs

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1. scibot 13 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113751
  
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sciencedirect.com/science/article/pii/S2211124724000792
Dec 2023
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Comparing HD knockin pigs and mice reveals the pathological role of IL-17

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  DOI: 10.1016/j.celrep.2023.113443
  
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sciencedirect.com/science/article/pii/S2211124723014559
Sep 2023
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Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.ccell.2023.08.014
  
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sciencedirect.com/science/article/abs/pii/S153561082300315X
Aug 2023
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Commensal bacteria promote azathioprine therapy failure in inflammatory bowel disease via decreasing 6-mercaptopurine bioavailability

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.xcrm.2023.101153
  
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sciencedirect.com/science/article/pii/S2666379123003063
Jul 2023
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Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy

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1. scibot 14 Jul 2023
  
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  DOI: 10.1038/s41467-023-39759-w
  
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  DOI: 10.1038/s41467-023-39759-w
  
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  DOI: 10.1038/s41467-023-39759-w
  
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Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH

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cd-22-0411-html.html

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Jun 2023
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DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs

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HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery

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May 2023
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Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity

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The importance of the timing of microbial signals for perinatal immune system development

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Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response

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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

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Mar 2023
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Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

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Recombinant vesicular stomatitis virus-vectored vaccine induces long lasting immunity against Nipah virus disease

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Dec 2022
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Metabolism-dependent ferroptosis promotes mitochondrial dysfunction and inflammation in CD4+ T lymphocytes in HIV-infected immune non-responders

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RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice

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STAT3 promotes differentiation of monocytes to MDSCs via CD39/CD73-adenosine signal pathway in oral squamous cell carcinoma

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Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro

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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

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Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity

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Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides

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Jun 2021
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Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors

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Multimodal analysis for human ex vivo studies shows extensive molecular changes from delays in blood processing

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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development

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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

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Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq

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  DOI: 10.7554/eLife.63632
  
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Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment

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cell.com/cell-metabolism/fulltext/S1550-4131(21)00130-3