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Fungal lipase LipA disarms macrophages by remodeling their lipidome, enabling full virulence in immunocompetent hosts

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1. scibot 17 Sep 2026
  
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  DOI: 10.1016/j.celrep.2026.117978
  
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sciencedirect.com/science/article/pii/S2211124726010569
Jan 2026
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Controlled pyroptosis of engineered macrophages enables biphasic antitumor via the release of oncolytic bacteria and inflammatory signals

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116918
  
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Pregnenolone promotes immune evasion through blocking endogenous retrovirus expression

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1. scibot 27 Jan 2026
  
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  DOI: 10.1016/j.cmet.2025.12.020
  
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sciencedirect.com/science/article/pii/S1550413125005844
journals.asm.org journals.asm.org

Synergistic effects of Clostridium butyricum and Akkermansia muciniphila-derived postbiotics ameliorate DSS-induced colitis and associated tumorigenesis through immunomodulation and microbiota regulation in mice

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1. scibot 06 Jan 2026
  
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  DOI: 10.1128/msystems.00689-25
  
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journals.asm.org/doi/10.1128/msystems.00689-25
Dec 2025
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Restricting lipid accumulation in tumor-infiltrating neutrophils mediates caloric restriction-induced anti-cancer effects

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.007
  
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sciencedirect.com:5037/science/article/pii/S1550413125004917
Jul 2025
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Activity-attenuated serum albumin-fused interleukin-33 suppresses experimental autoimmune encephalomyelitis

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102231
  
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sciencedirect.com/science/article/pii/S2666379125003040
Jun 2025
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Itaconate promotes inflammatory responses in tissue-resident alveolar macrophages and exacerbates acute lung injury

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.cmet.2025.05.012
  
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Feb 2025
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The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8+ T cells in mice

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1. scibot 20 Feb 2025
  
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  DOI: 10.1128/msystems.01567-24
  
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sciencedirect.com/org/science/article/pii/S2379507725000066
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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115273
  
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sciencedirect.com/science/article/pii/S2211124725000440
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

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1. scibot 02 Sep 2022
  
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  DOI: 10.1158/2159-8290.CD-21-0694
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904293/