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Aug 2026
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Humanizing acidic mammalian chitinase variants establish lung immune conditioning and control environmentally driven inflammation and fibrosis

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1. scibot 14 Aug 2026
  
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  DOI: 10.1016/j.celrep.2026.117833
  
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sciencedirect.com/science/article/pii/S2211124726009113
Jul 2026
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Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially regulate T-cell phenotype and function

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1. scibot 14 Jul 2026
  
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  DOI: 10.1093/jimmun/vkag165
  
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Jun 2026
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The transcription factor Eomes drives a stemness program in CD4+ T cells that promotes anti-tumor immunity in response to immunotherapy

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1. scibot 26 Jun 2026
  
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Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias

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1. scibot 18 Jun 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0920
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13271017/
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YB-1 inhibition suppresses osteosarcoma growth and reverses tumor immunosuppression

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1. scibot 13 Jun 2026
  
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  DOI: 10.1158/1535-7163.MCT-25-1240
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13249438/
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Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity

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May 2026
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IL-1R2 Deficiency Unleashes Neutrophil-Mediated Antitumor Potential in Sarcoma

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1. scibot 05 May 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0651
  
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aacrjournals.org/cancerimmunolres/article/14/5/751/784456/IL1R2-Deficiency-Unleashes-Neutrophil-Mediated
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NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency

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Apr 2026
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E-cadherin expression promotes tumor growth via KLRG1-dependent pathways

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1. scibot 28 Apr 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13108842/
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Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117303
  
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The weight-loss-independent hepatoprotective benefits of semaglutide are orchestrated by intrahepatic sinusoidal endothelial GLP-1 receptors

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1. scibot 16 Apr 2026
  
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Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome

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1. scibot 09 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.02.005
  
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Jan 2026
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Tumor-antigen-independent targeting of solid tumors by armored macrophage-directed anti-TREM2 CAR T cells

1
1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.11.009
  
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sciencedirect.com/science/article/pii/S1535610825005021
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Myelin antigen capture in the CNS by B cells expressing EBV latent membrane protein 1 leads to demyelinating lesion formation

1
1. scibot 15 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.031
  
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sciencedirect.com/science/article/pii/S0092867425014801
Dec 2025
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Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation

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1. scibot 11 Dec 2025
  
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  DOI: 10.1126/science.adr6322
  
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science.org/doi/10.1126/science.adr6322
Nov 2025
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Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapy

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.030
  
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.004
  
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Oct 2025
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2025.09.30.679035v1.full-html.html

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1. scibot 07 Oct 2025
  
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  AB_2870186
  
  DOI: 10.1101/2025.09.30.679035
  
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54.241.53.176/1390f297109f2e16a9738b79abd402ec0b331d3c/2025.09.30.679035v1.full-html.html
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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1. scibot 04 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
Sep 2025
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Evolution of a melanoma that escapes allogeneic rejection

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  DOI: 10.1016/j.celrep.2025.116288
  
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Harnessing Distinct Tissue-Resident Immune Niches via S100A9/TLR4 Improves Ketone, Lipid, and Glucose Metabolism

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1. scibot 10 Sep 2025
  
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  DOI: 10.1210/endocr/bqaf131
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12416535/
Aug 2025
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A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma

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1. scibot 06 Aug 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
Jul 2025
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Naturalized immune responses are stable over years in a colony of laboratory mice with wild-derived microbiota

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1. scibot 29 Jul 2025
  
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Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation

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1. scibot 08 Jul 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0415
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223510/
Jun 2025
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Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115861
  
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FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression

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  DOI: 10.1016/j.cmet.2025.05.011
  
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Neurodevelopmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.neuron.2025.05.016
  
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sciencedirect.com/science/article/pii/S0896627325003630
May 2025
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Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.03.021
  
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Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115642
  
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Mar 2025
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Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.017
  
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Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy

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  DOI: 10.1016/j.celrep.2025.115388
  
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sciencedirect.com/science/article/pii/S2211124725001597
Feb 2025
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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115294
  
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In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.immuni.2025.01.009
  
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sciencedirect.com/science/article/pii/S1074761325000342
Oct 2024
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Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.ebiom.2024.105347
  
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sciencedirect.com/science/article/pii/S2352396424003839
Sep 2024
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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

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1. scibot 27 Sep 2024
  
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  AB_2870186
  
  DOI: 10.1016/j.xcrm.2024.101747
  
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sciencedirect.com/science/article/pii/S2666379124004774
Aug 2024
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Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.xcrm.2024.101698
  
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.018
  
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Jul 2024
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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  DOI: 10.1016/j.celrep.2024.114506
  
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Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity

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  DOI: 10.1016/j.xcrm.2024.101640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293343/
Jun 2024
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Therapeutic potential of co-signaling receptor modulation in hepatitis B

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  DOI: 10.1016/j.cell.2024.05.038
  
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Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

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  DOI: 10.1016/j.immuni.2024.05.018
  
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Jan 2024
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Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

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  DOI: 10.1016/j.ccell.2023.12.013
  
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Dec 2023
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Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

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  DOI: 10.1016/j.cell.2023.11.002
  
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Aug 2023
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Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy

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  DOI: 10.1016/j.ccell.2023.08.001
  
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Jul 2023
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Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks

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  DOI: 10.1016/j.immuni.2023.06.020
  
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Jun 2023
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The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells

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  DOI: 10.1016/j.immuni.2023.05.008
  
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Apr 2023
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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  DOI: 10.1126/sciimmunol.abq7432
  
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Jan 2023
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Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2

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  DOI: 10.1016/j.celrep.2023.112038
  
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Dec 2022
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Cancer cell-derived type I interferons instruct tumor monocyte polarization

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  DOI: 10.1016/j.celrep.2022.111769
  
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Nov 2022
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Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis

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  DOI: 10.1016/j.celrep.2022.111611
  
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Oct 2022
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IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation

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  DOI: 10.1101/2021.08.20.21261620
  
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Jun 2022
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Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity

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  DOI: 10.1016/j.isci.2022.104435
  
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Apr 2022
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Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches

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  DOI: 10.1016/j.immuni.2022.03.006
  
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  DOI: 10.1016/j.immuni.2022.03.006
  
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Jan 2022
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Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

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  DOI: 10.1016/j.cell.2021.12.039
  
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Nov 2021
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Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells

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  DOI: 10.1016/j.celrep.2021.110013
  
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Jul 2021
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COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge

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