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A systemic circadian nicotinic acid riboside (NaR) signal engages the unfolded protein response and adipogenesis via the prefoldin complex

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1. scibot 15 Oct 2026
  
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  DOI: 10.1016/j.celrep.2026.118136
  
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sciencedirect.com/science/article/pii/S2211124726012155
Oct 2026
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HCMV US30 induces TMED10-DRP1-mediated mitochondrial fission and apoptosis to promote viral multiplication

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1. scibot 01 Oct 2026
  
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  DOI: 10.1128/mbio.01740-26
  
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journals.asm.org/doi/10.1128/mbio.01740-26
Aug 2026
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Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer

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1. scibot 20 Aug 2026
  
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  DOI: 10.1038/s44321-026-00506-5
  
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link.springer.com/article/10.1038/s44321-026-00506-5
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Coordinated transcriptional networks program organelle expansion and metabolic flows for high endothelial morphology and function

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1. scibot 12 Aug 2026
  
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  DOI: 10.1016/j.immuni.2026.07.014
  
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sciencedirect.com/science/article/pii/S1074761326003134
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A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer

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1. scibot 04 Aug 2026
  
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  DOI: 10.1016/j.ccell.2026.07.003
  
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sciencedirect.com/science/article/pii/S1535610826003120
Jun 2026
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Exosomal misfolded α1-antitrypsin triggers a cytosolic GRP78-dependent unfolded protein response and pro-survival signaling in pre-metastatic tissues

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1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.jbc.2026.113282
  
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sciencedirect.com/science/article/pii/S002192582602154X
May 2026
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Taxane chemotherapy promotes response to TIM-3 checkpoint blockade via STING-mediated ER stress and HMGB1 secretion

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102788
  
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sciencedirect.com/science/article/pii/S2666379126002053
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness

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1. scibot 06 May 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-4635
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
Apr 2026
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Wntless degradation mediated by CaMKII inhibition drives endoplasmic reticulum stress and apoptosis

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1. scibot 15 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117256
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13266901/
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Rational discovery of therapeutic PAK1 allosteric activators

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.03.008
  
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sciencedirect.com/science/article/pii/S0092867426002758
Feb 2026
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BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.01.012
  
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sciencedirect.com/science/article/pii/S1097276526000328
Nov 2025
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Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality

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1. scibot 19 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113770
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12616019/
May 2025
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Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115632
  
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sciencedirect.com/science/article/pii/S2211124725004036
Apr 2025
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Aberrant phase separation drives membranous organelle remodeling and tumorigenesis

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.04.001
  
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sciencedirect.com/science/article/pii/S1097276525003041
Jan 2025
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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

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1. scibot 17 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101913
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
Dec 2024
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IFRD1 is required for maintenance of bladder epithelial homeostasis

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1. scibot 13 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111282
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11613175/
Nov 2024
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Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111372
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11625362/
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Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114972
  
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sciencedirect.com/science/article/pii/S2211124724013238
May 2024
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Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression

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1. scibot 08 May 2024
  
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  RRID:AB_2891025
  
  DOI: 10.1016/j.cmet.2024.04.014
  
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sciencedirect.com/science/article/pii/S1550413124001347
Apr 2024
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ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114156
  
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sciencedirect.com/science/article/pii/S2211124724004844
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The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection

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1. scibot 23 Apr 2024
  
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  DOI: 10.1016/j.bbadis.2024.167193
  
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sciencedirect.com/science/article/pii/S0925443924001820
Dec 2023
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Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis

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1. scibot 14 Dec 2023
  
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  DOI: 10.1016/j.molmet.2023.101851
  
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sciencedirect.com/science/article/pii/S2212877823001850
Jun 2023
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Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.cmet.2023.05.009
  
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sciencedirect.com/science/article/pii/S1550413123001869
Jan 2023
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Palmitoylation couples insulin hypersecretion with β cell failure in diabetes

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1. scibot 13 Jan 2023
  
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  DOI: 10.1016/j.cmet.2022.12.012
  
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sciencedirect.com/science/article/pii/S1550413122005496
Sep 2022
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.ccell.2022.08.016
  
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sciencedirect.com/science/article/pii/S1535610822003804
Jul 2022
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FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity

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1. scibot 06 Jul 2022
  
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  DOI: 10.1016/j.cmet.2022.06.007
  
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sciencedirect.com/science/article/pii/S1550413122002273
Mar 2022
rupress.org rupress.org

PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen

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1. scibot 17 Mar 2022
  
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  DOI: 10.1084/jem.20211498
  
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rupress.org/jem/article/219/4/e20211498/213062/PERK-reprograms-hematopoietic-progenitor-cells-to
Oct 2021
academic.oup.com academic.oup.com

Insulin increases adipose adiponectin in pregnancy by inhibiting ubiquitination and degradation: Impact of obesity

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1. scibot 01 Oct 2021
  
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  DOI: 10.1210/clinem/dgab680
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab680/6370132