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Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116623
  
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sciencedirect.com:5037/science/article/pii/S2211124725013956
Nov 2025
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FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI

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1. scibot 23 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113515
  
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C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.neuron.2025.10.022
  
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Monocyte-derived cells promote transient insult-induced brain injury by enhancing CD8+ T cell response

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116528
  
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Sep 2025
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FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI

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1. scibot 23 Sep 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12494575/
Jul 2025
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ARID1A mutation drives gastric tumorigenesis via activating type 2 immune dominant microenvironment

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1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113117
  
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Combined KRAS inhibition and immune therapy generates durable complete responses in an autochthonous PDAC model

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1. scibot 15 Jul 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0489
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11858029/
Apr 2025
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TCF19/CDKN2A Regulates Glycolysis and Macrophage M2 Polarization for Osteosarcoma Progression

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1. scibot 10 Apr 2025
  
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  DOI: 10.1096/fj.202401343RRR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401343RRR
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Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.02.007
  
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sciencedirect.com/science/article/pii/S0092867425001928
Mar 2025
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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.devcel.2025.02.016
  
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sciencedirect.com/science/article/pii/S1534580725001212
Feb 2025
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Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

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1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2024.101927
  
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Jan 2025
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Revealing the role of cancer-associated fibroblast senescence in prognosis and immune landscape in pancreatic cancer

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111612
  
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sciencedirect.com/science/article/pii/S2589004224028396
Nov 2024
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NOD2 protects against allergic lung inflammation in obese female mice

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1. scibot 10 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111130
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11539594/
Oct 2024
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Electrical stimulation with polypyrrole-coated polycaprolactone/silk fibroin scaffold promotes sacral nerve regeneration by modulating macrophage polarisation

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1. scibot 01 Oct 2024
  
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  DOI: 10.12336/biomatertransl.2024.02.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11438605/
Sep 2024
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Granulocyte colony stimulating factor promotes scarless tissue regeneration

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114742
  
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sciencedirect.com/science/article/pii/S2211124724010933
Jul 2024
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Approaches to scarless burn wound healing: application of 3D printed skin substitutes with dual properties of anti-infection and balancing wound hydration levels

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.ebiom.2024.105258
  
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sciencedirect.com/science/article/pii/S2352396424002949
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Melatonin alleviates high-fat-diet-induced dry eye by regulating macrophage polarization via IFT27 and lowering ERK/JNK phosphorylation

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1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110367
  
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sciencedirect.com/science/article/pii/S258900422401592X
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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.chom.2024.06.003
  
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cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
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Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
Jun 2024
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Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer

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1. scibot 07 Jun 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-0519
  
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aacrjournals.org/cancerres/article/84/11/1834/745520/Obesogenic-High-Fat-Diet-and-MYC-Cooperate-to
Mar 2024
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Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression

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1. scibot 20 Mar 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0513
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10946310/
Dec 2023
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FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation

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1. scibot 20 Dec 2023
  
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  DOI: 10.1158/0008-5472.CAN-23-1065
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.002
  
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can-23-1065-html.html

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52.53.155.43/9a4ebc518d925889ddaa33b397b4737aebb3357f/can-23-1065-html.html
Nov 2023
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Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113430
  
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Jul 2023
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Cyclo (MQCNS) has the potential to treat ischemic stroke

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1. scibot 25 Jul 2023
  
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  DOI: 10.4103/1673-5374.371367
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10360098/
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Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

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1. scibot 22 Jul 2023
  
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  DOI: 10.1016/j.xcrm.2023.101129
  
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May 2023
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Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling

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1. scibot 23 May 2023
  
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  DOI: 10.1186/s13046-023-02696-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10199643/
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Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer

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1. scibot 05 May 2023
  
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  DOI: 10.1158/0008-5472.CAN-22-0410
  
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aacrjournals.org/cancerres/article/82/13/2458/705024/Transcriptional-Repression-by-FoxM1-Suppresses
Feb 2023
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A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

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1. scibot 16 Feb 2023
  
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sciencedirect.com/science/article/pii/S1074761323000407
Nov 2022
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Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis

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1. scibot 05 Nov 2022
  
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  DOI: 10.1016/j.ebiom.2022.104312
  
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Oct 2022
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Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy

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1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.cmet.2022.09.021
  
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sciencedirect.com/science/article/pii/S1550413122004119