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Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

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1. scibot 11 Feb 2026
  
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  DOI: 10.1083/jcb.202501207
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12885221/
Jan 2026
54.241.53.176 54.241.53.176

2026.01.09.698661v1.full-html.html

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1. scibot 13 Jan 2026
  
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  DOI: 10.64898/2026.01.09.698661
  
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54.241.53.176/229f150d292937106a4e15fcfbf1923f59503af0/2026.01.09.698661v1.full-html.html
Nov 2025
www.cell.com www.cell.com

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions

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1. scibot 06 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.013
  
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cell.com/cell/fulltext/S0092-8674(25)01178-X
Oct 2025
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HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116382
  
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sciencedirect.com/science/article/pii/S2211124725011532
Jul 2025
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Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of intestinal stemness

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115949
  
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sciencedirect.com/science/article/pii/S221112472500720X
Jun 2025
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Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.devcel.2025.05.016
  
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sciencedirect.com/science/article/pii/S1534580725003272
Apr 2025
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DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation

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1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.031
  
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sciencedirect.com/science/article/pii/S0092867425003496
Feb 2025
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OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

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1. scibot 27 Feb 2025
  
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  DOI: 10.1038/s44319-024-00361-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
Jan 2025
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1-s2.0-S2589004225001324-main-html.html

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1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.isci.2025.111872
  
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sciencedirect.com/science/article/pii/S2589004225001324
Dec 2024
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Neural circuit-specialized astrocytes: transcriptomic, proteomic, morphological and functional evidence

1
1. scibot 17 Dec 2024
  
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  RRID:AB_291263
  
  DOI: 10.1016/j.neuron.2017.06.029
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5811312/
Sep 2024
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ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.cell.2019.02.009
  
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sciencedirect.com/science/article/pii/S0092867419301588
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Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia

1
1. scibot 25 Sep 2024
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.celrep.2018.09.046
  
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sciencedirect.com/science/article/pii/S2211124718314918
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Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration

1
1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.devcel.2024.08.009
  
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sciencedirect.com/science/article/pii/S1534580724004921
Aug 2024
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Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation

1
1. scibot 20 Aug 2024
  
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  AB_291262
  
  DOI: 10.1016/j.molcel.2024.07.013
  
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sciencedirect.com/science/article/pii/S1097276524005896
Jun 2024
www.cell.com www.cell.com

POT1 recruits and regulates CST-Polα/primase at human telomeres

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.002
  
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cell.com/cell/fulltext/S0092-8674(24)00493-8
Apr 2024
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Protocol to detect OLA1 polyubiquitination by Aurora A in vivo and in vitro

2
1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.xpro.2024.103008
  
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2. scibot 18 Apr 2024
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.xpro.2024.103008
  
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sciencedirect.com/science/article/pii/S2666166724001734
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

1
1. scibot 22 Mar 2024
  
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  DOI: 10.1038/s41467-024-46760-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10950897/
Dec 2023
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Unraveling the mechanisms and evolution of a two-domain module in IQGAP proteins for controlling eukaryotic cytokinesis

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113510
  
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sciencedirect.com/science/article/pii/S221112472301522X
Oct 2023
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Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.chom.2023.08.018
  
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sciencedirect.com/science/article/pii/S1931312823003438
Sep 2023
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MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy

1
1. scibot 14 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113120
  
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sciencedirect.com/science/article/pii/S2211124723011324
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Mammalian autophagosomes form from finger-like phagophores

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1. scibot 08 Sep 2023
  
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  AB_10063630
  
  DOI: 10.1016/j.devcel.2023.08.016
  
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sciencedirect.com/science/article/pii/S1534580723004100
Aug 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

2
1. scibot 17 Aug 2023
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.celrep.2023.112957
  
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2. scibot 10 Aug 2023
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.celrep.2023.112957
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10542749/
Jul 2023
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Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112850
  
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sciencedirect.com/science/article/pii/S2211124723008616
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glial-dependent clustering of voltage-gated ion channels in Drosophila precedes myelin formation

1
1. scibot 24 Jun 2023
  
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  RRID:AB_291262
  
  DOI: 10.7554/eLife.85752
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10287160/
May 2023
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The adhesion GPCRs CELSR1–3 and LPHN3 engage G proteins via distinct activation mechanisms

1
1. scibot 24 May 2023
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.celrep.2023.112552
  
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sciencedirect.com/science/article/pii/S2211124723005636
insight.jci.org insight.jci.org

Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans

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1. scibot 11 May 2023
  
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  RRID:AB_291262
  
  DOI: 10.1172/jci.insight.168448
  
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insight.jci.org/articles/view/168448
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

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1. scibot 20 Apr 2023
  
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  RRID:AB_291262
  
  DOI: 10.1158/2767-9764.CRC-23-0086
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10108886/
Nov 2022
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Mitotic phosphorylation inhibits the Golgi mannosidase MAN1A1

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1. scibot 24 Nov 2022
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.celrep.2022.111679
  
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sciencedirect.com/science/article/pii/S2211124722015534
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

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1. scibot 22 Apr 2022
  
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  DOI: 10.1371/journal.pgen.1010150
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9020716/
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains

1
1. scibot 04 Mar 2022
  
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  RRID:AB_291262
  
  DOI: 10.7554/eLife.74447
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8856730/
Jan 2022
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HsfA7 coordinates the transition from mild to strong heat stress response by controlling the activity of the master regulator HsfA1a in tomato

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1. scibot 12 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110224
  
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sciencedirect.com/science/article/pii/S2211124721017289
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts

1
1. scibot 29 Nov 2021
  
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  RRID:AB_291262
  
  DOI: 10.1016/j.neuron.2019.02.034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy

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1. scibot 05 Nov 2021
  
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  RRID:AB_291262
  
  DOI: 10.7554/eLife.65759
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8550759/
Oct 2021
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A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle

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Parasitic modulation of host development by ubiquitin-independent protein degradation

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Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis

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Untitled document

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Selective overexpression of Collybistin in mouse hippocampal pyramidal cells enhances GABAergic neurotransmission and protects against PTZ-induced seizures

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Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction

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PDZ domain protein SYNJ2BP regulates GRK-dependent Sst2A phosphorylation and downstream MAPK signaling

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DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1

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Comprehensive Analysis of G1 Cyclin Docking Motif Sequences that Control CDK Regulatory Potency In Vivo

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Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism

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A gradient of Wnt activity positions the neurosensory domains of the inner ear

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The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome

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Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation

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cell.com/molecular-cell/fulltext/S1097-2765(20)30836-4
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A microtubule‐LUZP1 association around tight junction promotes epithelial cell apical constriction

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sncRiboTag-Seq: cell-type-specific RiboTag-Seq for cells in low abundance in mouse brain tissue

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An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2

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The Proteomic Landscape of Centromeric Chromatin Reveals an Essential Role for the Ctf19CCAN Complex in Meiotic Kinetochore Assembly

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Evaluation of Engineered CRISPR-Cas-Mediated Systems for Site-Specific RNA Editing

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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

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Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing

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Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis

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Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation

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RGS6 Mediates Effects of Voluntary Running on Adult Hippocampal Neurogenesis

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Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus

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Untitled document

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Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects

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  Ani-HA, mouse monoclonal
  
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PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation

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AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

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Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism

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Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation

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PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis

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The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice

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Differential mitochondrial morphology in ventral striatal projection neuron subtypes

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β-blockers augment L-type Ca2+ channel activity by targeting spatially restricted β2AR signaling in neurons

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Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming

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DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4

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Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence

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Late rDNA Condensation Ensures Timely Cdc14 Release and Coordination of Mitotic Exit Signaling with Nucleolar Segregation

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11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation

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Interaction between optineurin and Rab1a regulates autophagosome formation in neuroblastoma cells

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Mitosis can drive cell cannibalism through entosis

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