64 Matching Annotations
  1. Oct 2025
  2. www.sciencedirect.com www.sciencedirect.com
    PNPLA3-I148M is a neomorph that interferes with two primary hepatic triglyceride clearance pathways
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    sciencedirect.com/science/article/pii/S2211124725011428
  3. Sep 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The desmosome-intermediate filament system facilitates mechanotransduction at adherens junctions for epithelial homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11387132/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12383277/
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    ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation
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    sciencedirect.com/science/article/pii/S2211124725010010
  7. www.science.org www.science.org
    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    science.org/doi/10.1126/sciadv.ady0240
  8. Aug 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The protease-activated receptors are expressed in glioblastoma and differentially modulate adherent versus stem-like growth of LN-18 GBM cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12321897/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Valproic acid improves the efficacy of oxaliplatin/fluoropyrimidine-based chemotherapy by targeting cancer stem cell via β-Catenin modulation in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316941/
  11. Jul 2025
  12. www.science.org www.science.org
    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    science.org/doi/10.1126/sciadv.adw5228
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exposing the DNA methylation-responsive compartment of the leukaemic genome in T-ALL cell lines support its potential as a novel therapeutic target in T-ALL
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224799/
  14. www.biorxiv.org www.biorxiv.org
    Integrated genetic screening reveals FEN1 as a driver of stemness and temozolomide resistance in glioblastoma
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    biorxiv.org/content/10.1101/2025.06.18.660339v1
  15. Jun 2025
  16. www.cell.com www.cell.com
    TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89
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    cell.com/cell-reports/abstract/S2211-1247(25)00454-1
  17. www.nature.com www.nature.com
    DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation
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    nature.com/articles/s41594-025-01581-x
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantification of Folded and Misfolded Proinsulin Forms Using Nonreducing SDS-PAGE and Proinsulin-Specific Immunoblotting
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    pmc.ncbi.nlm.nih.gov/articles/PMC12152102/
  19. www.sciencedirect.com www.sciencedirect.com
    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2211124725005637
  20. May 2025
  21. link.springer.com link.springer.com
    Microglia-driven inflammation induces progressive tauopathies and synucleinopathies
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    link.springer.com/article/10.1038/s12276-025-01450-z
  22. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225009125-main-html.html
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    Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
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    sciencedirect.com/science/article/pii/S2211124725004929
  24. Apr 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12014135/
  26. www.sciencedirect.com www.sciencedirect.com
    Treatment of IL-18-binding protein biologics suppresses fibrotic progression in metabolic dysfunction-associated steatohepatitis
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    sciencedirect.com/science/article/pii/S266637912500120X
  27. www.sciencedirect.com www.sciencedirect.com
    HMGA1 deficiency: a pathogenic link between tau pathology and insulin resistance
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    sciencedirect.com/science/article/pii/S2352396425001446
  28. Mar 2025
  29. www.sciencedirect.com www.sciencedirect.com
    Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia
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    sciencedirect.com/science/article/pii/S1535610825000601
  30. www.sciencedirect.com www.sciencedirect.com
    PIEZO1-dependent mode switch of neuronal migration in heterogeneous microenvironments in the developing brain
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    sciencedirect.com/science/article/pii/S2211124725001767
  31. Feb 2025
  32. www.sciencedirect.com www.sciencedirect.com
    OAS cross-activates RNase L intercellularly through cell-to-cell transfer of 2-5A to spread innate immunity
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    sciencedirect.com/science/article/pii/S1074761325000652
  33. dx.doi.org dx.doi.org
    Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium
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    dx.doi.org/10.1210/endocr/bqae123
  34. 52.53.155.43 52.53.155.43
    AQP1- A regulatory factor associated with brown adipose tissue-silencing
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    52.53.155.43/2dcbfaa0dcc73a4d1082a5a710760ab9fbf9ca77/2024.09.23.614599.full-html.html
  35. Jan 2025
  36. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/7f7c624c4b3ef1ab723ec0888e5ac5b85eebf074/PDF-html.html
  37. www.mdpi.com www.mdpi.com
    Isolation and Characterization of Antibodies Against Vascular Cell Adhesion Molecule-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction
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    mdpi.com/1422-0067/25/24/13650
  38. www.sciencedirect.com www.sciencedirect.com
    Revisiting phosphoregulation of Cdc25C during M-phase induction
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    sciencedirect.com/science/article/pii/S258900422402830X
  39. Dec 2024
  40. aacrjournals.org aacrjournals.org
    Clotting Promotes Glioma Growth and Infiltration Through Activation of Focal Adhesion Kinase
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    aacrjournals.org/cancerrescommun/article/4/12/3124/750544/Clotting-Promotes-Glioma-Growth-and-Infiltration
  41. 52.53.155.43 52.53.155.43
    TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons
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    52.53.155.43/a78570202c237c34caff8d9dcc5ffd9013c3700f/1-s2.0-S2589004224027421-main-html.html
  42. Oct 2024
  43. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ERK1/2 mitogen-activated protein kinase dimerization is essential for the regulation of cell motility
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13732
  44. Sep 2024
  45. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17319
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial bioenergetics and cardiolipin remodeling abnormalities in mitochondrial trifunctional protein deficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC11385086/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacterial pore-forming toxin pneumolysin drives pathogenicity through host extracellular vesicles released during infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11357855/
  48. www.sciencedirect.com www.sciencedirect.com
    A spinal and bulbar muscular atrophy (SBMA) disease-specific human embryonic stem cell (hESC) line, UMICHe002-A/UM197-1
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    sciencedirect.com/science/article/pii/S1873506124002460
  49. Aug 2024
  50. www.sciencedirect.com www.sciencedirect.com
    tRNA-m1A methylation controls the infection of Magnaporthe oryzae by supporting ergosterol biosynthesis
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    sciencedirect.com/science/article/pii/S1534580724004854
  51. Jun 2024
  52. www.sciencedirect.com www.sciencedirect.com
    K29-linked free polyubiquitin chains affect ribosome biogenesis and direct ribosomal proteins to the intranuclear quality control compartment
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    sciencedirect.com/science/article/pii/S1097276524004416
  53. May 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss
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    sciencedirect.com/science/article/pii/S2666379124002660
  55. link.springer.com link.springer.com
    Characterization of a novel HDAC2 pathogenetic variant: a missing puzzle piece for chromatinopathies
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    link.springer.com/article/10.1007/s00439-024-02675-0
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11149630/
  57. Apr 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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    sciencedirect.com/science/article/pii/S1534580724001990
  59. www.sciencedirect.com www.sciencedirect.com
    A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity
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    sciencedirect.com/science/article/pii/S0960982224003129
  60. Mar 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951640/
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Unmoving and uninflamed: Characterizing neuroinflammatory dysfunction in the Wistar-Kyoto rat model of depression
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16083
  63. Feb 2024
  64. www.sciencedirect.com www.sciencedirect.com
    RNF4 prevents genomic instability caused by chronic DNA under-replication
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    sciencedirect.com/science/article/pii/S1568786424000223
  65. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
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    52.53.155.43/d3d22b34dc913e3c2adad8dc51a7839208721c99/PIIS2589004224003213-html.html
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxin-mediated silk gland organ dysfunction diverts resources to enhance silkworm fecundity by potentiating nutrient-sensing IIS/TOR pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830876/
  67. Dec 2023
  68. www.sciencedirect.com www.sciencedirect.com
    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
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    sciencedirect.com/science/article/pii/S2211124723015528
  69. www.sciencedirect.com www.sciencedirect.com
    MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet
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    sciencedirect.com/science/article/pii/S2589004223027736
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10725030/
  71. Nov 2023
  72. www.sciencedirect.com www.sciencedirect.com
    ABLs and TMKs are co-receptors for extracellular auxin
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    sciencedirect.com/science/article/pii/S0092867423011340
  73. Sep 2023
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a human Tropomyosin 1 knockout iPSC line
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    ncbi.nlm.nih.gov/pmc/articles/PMC10507314/
  75. Aug 2023
  76. www.sciencedirect.com www.sciencedirect.com
    A Zpr1 co-chaperone mediates folding of eukaryotic translation elongation factor 1A via a GTPase cycle
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    sciencedirect.com/science/article/abs/pii/S1097276523006019
  77. Jul 2023
  78. 52.53.155.43 52.53.155.43
    Generation of a human Tropomyosin 1 knockout iPSC line
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    52.53.155.43/19927600e3f5f01329481360cbf2dd4546ab9ef5/2023.05.03.539242.full-html.html
  79. www.sciencedirect.com www.sciencedirect.com
    Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles
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    sciencedirect.com/science/article/abs/pii/S1097276523004252
  80. Jun 2023
  81. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Characterization of Hofbauer cell polarization and VEGF localization in human term placenta from active and inactive pregnant individuals
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15741
  82. Apr 2023
  83. www.sciencedirect.com www.sciencedirect.com
    Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2667237523000759
  84. Mar 2023
  85. www.sciencedirect.com www.sciencedirect.com
    NanoB2 to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET
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    sciencedirect.com/science/article/pii/S2667237523000334
  86. Feb 2023
  87. www.sciencedirect.com www.sciencedirect.com
    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
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    sciencedirect.com/science/article/pii/S2211124723001407
  88. Dec 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC9682343/
  90. Oct 2022
  91. www.sciencedirect.com www.sciencedirect.com
    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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    sciencedirect.com/science/article/pii/S2451945622003555
  92. Sep 2022
  93. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012694
  94. Aug 2022
  95. www.sciencedirect.com www.sciencedirect.com
    Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival
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    sciencedirect.com/science/article/pii/S2589004222011816
  96. Jul 2022
  97. yc.mlpla.mil.cn yc.mlpla.mil.cn
    Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
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    yc.mlpla.mil.cn/s/com/sciencedirect/www/G.https/science/article/pii/S2451945622002392