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Gut microbiota-derived lysine phenylacetylation impairs mitochondrial function and is alleviated by SIRT3

1
1. scibot 26 Jun 2026
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.cmet.2026.05.016
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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RRID:AB_2942099

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sciencedirect.com/science/article/pii/S1550413126002263
Jun 2026
www.sciencedirect.com www.sciencedirect.com

RNF126 mediates fetal growth restriction via ubiquitination-dependent degradation of the MYH9/MYH10 complex

1
1. scibot 09 Jun 2026
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.isci.2026.116285
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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sciencedirect.com/science/article/pii/S2589004226016603
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

1
1. scibot 24 Apr 2026
  
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  RRID:AB_2942099
  
  DOI: 10.1002/advs.202509148
  
  Resource: RRID:AB_2942099
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:AB_2942099
  
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  RRIDCUR:Unresolved RRID:AB_2942099
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RRID:AB_2942099

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pmc.ncbi.nlm.nih.gov/articles/PMC12822389/
Feb 2026
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RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer

1
1. scibot 12 Feb 2026
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.molcel.2026.01.020
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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sciencedirect.com/science/article/pii/S1097276526000626
Jan 2026
link.springer.com link.springer.com

HAT1 Protects Against Cerebral Ischemia Injury by Inhibiting TFRC-Mediated Ferroptosis

1
1. scibot 06 Jan 2026
  
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  RRID:AB_2942099
  
  DOI: 10.1007/s11064-025-04640-3
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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link.springer.com/article/10.1007/s11064-025-04640-3
Aug 2025
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Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis

1
1. scibot 14 Aug 2025
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.devcel.2025.07.014
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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sciencedirect.com/science/article/pii/S153458072500471X
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SUCLG1 deficiency-induced histone succinylation impairs oncogene expression in acute myeloid leukemia

1
1. scibot 13 Aug 2025
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.celrep.2025.116147
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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sciencedirect.com/science/article/pii/S2211124725009180
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression

1
1. scibot 05 Aug 2025
  
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  RRID:AB_2942099
  
  DOI: 10.1158/0008-5472.CAN-24-3525
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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pmc.ncbi.nlm.nih.gov/articles/PMC12314509/
Jan 2025
www.sciencedirect.com www.sciencedirect.com

OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth

1
1. scibot 28 Jan 2025
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.molcel.2024.12.025
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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sciencedirect.com/science/article/pii/S1097276524010669
Dec 2024
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Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis

1
1. scibot 14 Dec 2024
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.celrep.2024.115060
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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sciencedirect.com/science/article/pii/S2211124724014116
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Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis

1
1. scibot 06 Dec 2024
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.cmet.2024.11.005
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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sciencedirect.com/science/article/pii/S1550413124004510
Nov 2024
www.sciencedirect.com www.sciencedirect.com

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.cmet.2024.10.015
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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sciencedirect.com/science/article/pii/S155041312400411X
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair

1
1. scibot 01 Jul 2024
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.isci.2024.110014
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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RRID:AB_2942099

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ncbi.nlm.nih.gov/pmc/articles/PMC11214487/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

1
1. scibot 09 Jun 2024
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.isci.2024.109991
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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RRID:AB_2942099

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ncbi.nlm.nih.gov/pmc/articles/PMC11154205/
May 2024
www.sciencedirect.com www.sciencedirect.com

Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro

1
1. scibot 30 May 2024
  
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  RRID:AB_2942099
  
  DOI: 10.1016/j.xpro.2024.103088
  
  Resource: (PTM BIO Cat# PTM-419, RRID:AB_2942099)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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sciencedirect.com/science/article/pii/S2666166724002533
Jan 2024
www.sciencedirect.com www.sciencedirect.com

OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB

1
1. scibot 11 Jan 2024
  
  in Public
  
  RRID:AB_2942099
  
  DOI: 10.1016/j.molcel.2023.11.042
  
  Resource: AB_2942099
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2942099
  
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  RRID:AB_2942099
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RRID:AB_2942099

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sciencedirect.com/science/article/pii/S1097276523010195