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PARP1 hyperactivation uncouples transcription from protein expression through nuclear RNA retention

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.molcel.2026.10.015
  
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UFSP2 constitutes a targetable vulnerability via deUFMylation-dependent activation of AKT oncogenic signaling

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1. scibot 03 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118214
  
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sciencedirect.com/science/article/pii/S2211124726012933
May 2026
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Nostoc commune Extract Attenuates Oxidative Stress and Neuroinflammation in Ischemic Optic Neuropathy Through PI3K/AKT/mTOR Signaling

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1. scibot 29 May 2026
  
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  DOI: 10.3390/antiox15050541
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13203249/
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The REDD1–NF-κB–miRNAs–eNOS/SIRT1 axis mediates obesity-induced endothelial cell senescence and hypertension

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1. scibot 15 May 2026
  
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  DOI: 10.1038/s41467-026-70601-1
  
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nature.com/articles/s41467-026-70601-1
Apr 2026
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Oxytocin signaling in adipocytes is required for normal milk fat production

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.cmet.2026.03.013
  
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sciencedirect.com/science/article/pii/S1550413126001075
Mar 2026
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Maltol induces diabetic fragility fractures by disrupting the balance of bone remodeling

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.cmet.2026.03.001
  
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sciencedirect.com/science/article/pii/S1550413126000951
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MYCT1–IFITM2/3 interaction links endothelial endolysosomal trafficking to white adipose tissue expansion

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1. scibot 27 Mar 2026
  
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  DOI: 10.1084/jem.20251497
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13016079/
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Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102695
  
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sciencedirect.com/science/article/pii/S2666379126001126
Feb 2026
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BPS Publications

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1. scibot 26 Feb 2026
  
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  DOI: 10.1111/bph.70353
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70353
Dec 2025
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Activated T cells degrade extracellular proteins to enhance effector functions

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1. scibot 25 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116797
  
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sciencedirect.com/science/article/pii/S2211124725015694
Nov 2025
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Lactylation of mTOR enhances autophagy in skeletal muscle during exercise

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.chembiol.2025.10.007
  
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sciencedirect.com/science/article/pii/S2451945625003447
Jul 2025
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PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth

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1. scibot 30 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116071
  
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Component Analysis of Saxifraga stolonifera Extract and Its Mechanism of Melanin Inhibition

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1. scibot 08 Jul 2025
  
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  DOI: 10.1002/cbdv.202500995
  
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onlinelibrary.wiley.com/doi/10.1002/cbdv.202500995
Jun 2025
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1-s2.0-S258900422501226X-main-html.html

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112965
  
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52.53.155.43/d1f78810f1eafd7cac950f9c8a5713f79fe4d700/1-s2.0-S258900422501226X-main-html.html
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Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor

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1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102133
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147910/
May 2025
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Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102133
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147910/
Mar 2025
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Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine

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1. scibot 21 Mar 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0261
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11921867/
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225003785-main-html.html

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1. scibot 28 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.112118
  
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52.53.155.43/d1f964056b3dd00ef17176fded1971b6e20e47a3/1-s2.0-S2589004225003785-main-html.html
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Dietary nitrate supplementation mitigates age-related changes at the neuromuscular junction in mice

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1. scibot 27 Feb 2025
  
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  DOI: 10.1113/JP287592
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP287592
Jan 2025
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Microenvironmental β-TrCP negates amino acid transport to trigger CD8+ T cell exhaustion in human non-small cell lung cancer

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115128
  
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sciencedirect.com/science/article/pii/S2211124724014797
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Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115125
  
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sciencedirect.com/science/article/pii/S2211124724014761
Jul 2024
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Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

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1. scibot 04 Jul 2024
  
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  DOI: 10.1101/2024.06.11.598518
  
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biorxiv.org/content/10.1101/2024.06.11.598518v2
Mar 2024
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Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats

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1. scibot 09 Mar 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
Feb 2024
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.012
  
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  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480