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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heterogeneous endocrine cell composition defines human islet functional phenotypes
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    1. scibot 21 Dec 2024
      RRID:AB_297642

      DOI: 10.1101/2024.11.20.623809

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    pmc.ncbi.nlm.nih.gov/articles/PMC11601672/
  3. Dec 2024
  4. www.cell.com www.cell.com
    Cycling alpha cells in regenerative drug-treated human pancreatic islets may serve as key beta cell progenitors
    1
    1. scibot 05 Dec 2024
      RRID:AB_297642

      DOI: 10.1016/j.xcrm.2024.101832

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    cell.com/cell-reports-medicine/abstract/S2666-3791(24)00603-7
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
    1
    1. scibot 25 Sep 2024
      AB_297642

      DOI: 10.1016/j.isci.2024.110767

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    sciencedirect.com/science/article/pii/S2589004224019928
  7. Apr 2024
  8. dx.doi.org dx.doi.org
    Structure-Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Bipartite Nuclear Localization Signal
    1
    1. scibot 04 Apr 2024
      RRID:AB_297642

      DOI: 10.1210/endocr/bqad197

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    dx.doi.org/10.1210/endocr/bqad197
  9. Feb 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of Metabolic Alterations in the Lean Metabolically Unhealthy Alpha Defensin Transgenic mice.
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108802

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839648/
  11. Jan 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells
    1
    1. scibot 18 Jan 2024
      AB_297642

      DOI: 10.1016/j.isci.2023.108725

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788290/
  13. Dec 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes
    1
    1. scibot 22 Dec 2023
      RRID:AB_297642

      DOI: 10.1016/j.cmet.2023.11.011

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    sciencedirect.com/science/article/pii/S1550413123004436
  15. Apr 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Steroidogenic factor 1 protects mice from obesity-induced glucose intolerance via improving glucose-stimulated insulin secretion by beta cells
    1
    1. scibot 09 Apr 2023
      RRID:AB_297642

      DOI: 10.1016/j.isci.2023.106451

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    ncbi.nlm.nih.gov/pmc/articles/PMC10068556/
  17. Mar 2023
  18. europepmc.org europepmc.org
    β-Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control
    1
    1. scibot 29 Mar 2023
      RRID:AB_297642

      DOI: 10.1111/1753-0407.13380

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    europepmc.org/article/med/36942376
  19. Dec 2022
  20. www.sciencedirect.com www.sciencedirect.com
    A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
    1
    1. scibot 02 Dec 2022
      RRID:AB_297642

      DOI: 10.1016/j.ebiom.2022.104379

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    sciencedirect.com/science/article/pii/S2352396422005618
  21. www.sciencedirect.com www.sciencedirect.com
    Glycemic control releases regenerative potential of pancreatic beta cells blocked by severe hyperglycemia
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111719

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    sciencedirect.com/science/article/pii/S2211124722015972
  22. Nov 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin
    1
    1. scibot 22 Nov 2022
      RRID:AB_297642

      DOI: 10.1016/j.ebiom.2022.104342

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    sciencedirect.com/science/article/pii/S2352396422005242
  24. academic.oup.com academic.oup.com
    Ageing Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Human
    1
    1. scibot 01 Nov 2022
      RRID:AB_297642

      DOI: 10.1210/clinem/dgac535

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac535/6705055
  25. Oct 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPCR-Mediated Regulation of Fuel and Energy Metabolism in Peripheral Tissues: Glucagon receptor signaling at white adipose tissue does not regulate lipolysis
    1
    1. scibot 27 Oct 2022
      RRID:AB_297642

      DOI: 10.1152/ajpendo.00078.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC9576180/
  27. academic.oup.com academic.oup.com
    Exocrine and Endocrine Inflammation Increases Cellular Replication in the Pancreatic Duct Compartment in Type 1 Diabetes
    1
    1. scibot 26 Oct 2022
      RRID:AB_297642

      DOI: 10.1210/jendso/bvac136

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    academic.oup.com/jes/article/6/11/bvac136/6691224
  28. Aug 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids
    1
    1. scibot 31 Aug 2022
      RRID:AB_297642

      DOI: 10.1016/j.xpro.2022.101656

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    sciencedirect.com/science/article/pii/S2666166722005366
  30. Jul 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells
    1
    1. scibot 13 Jul 2022
      RRID:AB_297642

      DOI: 10.1016/j.celrep.2022.111069

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    sciencedirect.com/science/article/pii/S2211124722008671
  32. Apr 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation
    1
    1. scibot 21 Apr 2022
      RRID:AB_297642

      DOI: 10.1016/j.devcel.2017.04.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC5425251/
  34. Mar 2022
  35. www.sciencedirect.com www.sciencedirect.com
    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
    1
    1. scibot 02 Mar 2022
      RRID:AB_297642

      DOI: 10.1016/j.celrep.2022.110425

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    sciencedirect.com/science/article/pii/S2211124722001498
  36. Dec 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated analysis of the pancreas and islets reveals unexpected findings in human male with type 1 diabetes
    1
    1. scibot 04 Dec 2021
      RRID:AB_297642

      DOI: 10.1210/jendso/bvab162

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633619/
  38. Oct 2021
  39. academic.oup.com academic.oup.com
    Preproglucagon Products and Their Respective Roles Regulating Insulin Secretion
    1
    1. scibot 01 Oct 2021
      RRID:AB_297642

      DOI: 10.1210/endocr/bqab150

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    academic.oup.com/endo/article/162/10/bqab150/6329397
  40. Aug 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 08 Aug 2021
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      DOI: 10.7554/eLife.39689

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    ncbi.nlm.nih.gov/pmc/articles/PMC6200393/
  42. elifesciences.org elifesciences.org
    Untitled document
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    1. scibot 01 Aug 2021
      RRID:AB_297642

      DOI: 10.7554/eLife.39689

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    elifesciences.org/articles/39689
  43. Jul 2021
  44. link.springer.com link.springer.com
    Altered cellular localisation and expression, together with unconventional protein trafficking, of prion protein, PrPC, in type 1 diabetes
    1
    1. scibot 20 Jul 2021
      ab10988

      DOI: 10.1007/s00125-021-05501-8

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    link.springer.com/article/10.1007/s00125-021-05501-8
  45. Jun 2021
  46. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment
    1
    1. scibot 03 Jun 2021
      RRID:AB_297642

      DOI: 10.1016/j.cmet.2021.05.013

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    sciencedirect.com/science/article/pii/S1550413121002308
  47. May 2021
  48. academic.oup.com academic.oup.com
    Proper mTORC1 activity is required for glucose sensing and early adaptation in human pancreatic beta cell
    1
    1. scibot 10 May 2021
      RRID:AB_297642

      DOI: 10.1210/clinem/dgaa786

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    academic.oup.com/jcem/article/106/2/e562/5943203
  49. Mar 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis
    1
    1. scibot 17 Mar 2021
      RRID:AB_297642

      DOI: 10.1016/j.celrep.2021.108830

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    sciencedirect.com/science/article/pii/S2211124721001443
  51. Feb 2021
  52. academic.oup.com academic.oup.com
    Using a reporter mouse to map known and novel sites of GLP-1 receptor expression in peripheral tissues of male mice
    1
    1. scibot 24 Feb 2021
      RRID:AB_297642

      DOI: 10.1210/endocr/bqaa246

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    academic.oup.com/endo/article/162/3/bqaa246/6054985
  53. Jan 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
    1
    1. scibot 13 Jan 2021
      AB_2917642

      DOI: 10.1101/gad.344556.120

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    ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
  55. Dec 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Autosomal Dominant Diabetes Associated with a Novel ZYG11A Mutation Resulting in Cell Cycle Arrest in Beta-Cells
    1
    1. scibot 20 Dec 2020
      anti-glucagon

      DOI: 10.1016/j.mce.2020.111126

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    sciencedirect.com/science/article/pii/S0303720720304287
  57. Nov 2020
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells
    1
    1. scibot 24 Nov 2020
      RRID:AB_297642

      DOI: 10.1016/j.cmet.2020.11.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC7664344/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19
    1
    1. scibot 24 Nov 2020
      RRID:AB_297642

      DOI: 10.1016/j.cmet.2020.11.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7664515/
  60. Sep 2020
  61. academic.oup.com academic.oup.com
    Dapagliflozin does not directly affect human α or β cells
    1
    1. scibot 25 Sep 2020
      RRID:AB_297642

      DOI: 10.1210/endocr/bqaa080

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    academic.oup.com/endo/article/161/8/bqaa080/5840747
  62. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Tetraspanin‐7 regulation of L‐type voltage‐dependent calcium channels controls pancreatic β‐cell insulin secretion
    1
    1. scibot 11 Sep 2020
      mouse anti‐glucagon

      DOI: 10.1113/JP279941

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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP279941
  63. www.sciencedirect.com www.sciencedirect.com
    Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion
    1
    1. scibot 11 Sep 2020
      RRID:AB_297642

      DOI: 10.1016/j.celrep.2020.107761

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    sciencedirect.com/science/article/pii/S2211124720307415
  64. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Microsoft Word - DB190554SupplementaryData.doc
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    1. scibot 03 Sep 2020
      AB_297642

      DOI: 10.2337/db19-0554

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    diabetes.diabetesjournals.org/content/diabetes/suppl/2019/10/09/db19-0554.DC1/DB190554SupplementaryData.pdf
  65. Jan 2020
  66. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
    1
    1. scibot 13 Jan 2020
      RRID:AB_297642

      DOI: 10.1016/j.cmet.2019.12.005

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    sciencedirect.com/science/article/pii/S1550413119306709
  67. academic.oup.com academic.oup.com
    Decreased beta cell proliferation and vascular density in a subpopulation of low-oxygenated male rat islets
    1
    1. scibot 13 Jan 2020
      RRID:AB_297642

      DOI: 10.1210/js.2019-00101

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    academic.oup.com/jes/article/3/8/1608/5516552
  68. Nov 2018
  69. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development
    1
    1. scibot 05 Nov 2018
      RRID:AB_297642

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    sciencedirect.com/science/article/pii/S155041311830576X
  70. www.sciencedirect.com www.sciencedirect.com
    Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes
    1
    1. scibot 05 Nov 2018
      RRID:AB_297642

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      RRID:AB_297642
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    sciencedirect.com/science/article/pii/S1550413118303942
  71. Nov 2017
  72. www.sciencedirect.com www.sciencedirect.com
    Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata
    1
    1. scibot 08 Nov 2017
      RRID:AB_297642

      Curator: @Jmenke

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      (Abcam Cat# ab10988, RRID:AB_297642)

      SciCrunch record: RRID:AB_297642

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_297642 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117304989
  73. www.sciencedirect.com www.sciencedirect.com
    Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation
    1
    1. scibot 08 Nov 2017
      AB_297642

      Curator: @chewbeccax

      Resource used:

      (Abcam Cat# ab10988, RRID:AB_297642)

      SciCrunch record: RRID:AB_297642

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      RRID:AB_297642 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117303005
  74. www.sciencedirect.com www.sciencedirect.com
    Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation
    1
    1. scibot 08 Nov 2017
      AB_297642

      Curator: @kaitlinsung

      Resource used:

      (Abcam Cat# ab10988, RRID:AB_297642)

      SciCrunch record: RRID:AB_297642

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      RRID:AB_297642 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717302976
  75. www.sciencedirect.com www.sciencedirect.com
    A Single-Cell Transcriptome Atlas of the Human Pancreas
    1
    1. scibot 08 Nov 2017
      AB_297642

      Curator: @gabimpine

      Resource used:

      (Abcam Cat# ab10988, RRID:AB_297642)

      SciCrunch record: RRID:AB_297642

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_297642 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2405471216302927