33 Matching Annotations
  1. Last 7 days
  2. www.nature.com www.nature.com
    Lithocholic acid phenocopies anti-ageing effects of calorie restriction
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      DOI: 10.1038/s41586-024-08329-5

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    nature.com/articles/s41586-024-08329-5
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    Light-dark shift promotes colon carcinogenesis through accelerated colon aging
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    sciencedirect.com/science/article/pii/S2589004224027871
  4. Oct 2024
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    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
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      DOI: 10.1016/j.xcrm.2024.101752

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    sciencedirect.com/science/article/pii/S2666379124004828
  6. Aug 2024
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    The adeno-associated virus 2 (AAV2) genome and rep 68/78 proteins interact with cellular sites of DNA damage
    1
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      DOI: 10.1093/hmg/ddab300

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    academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddab300/6397801
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    1. scibot 11 Apr 2024
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      DOI: 10.21037/tlcr-24-160

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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
  10. Feb 2024
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    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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      DOI: 10.1016/j.xcrm.2024.101434

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    sciencedirect.com/science/article/pii/S2666379124000570
  12. Dec 2023
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    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
    1
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      DOI: 10.1016/j.celrep.2023.113555

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    sciencedirect.com/science/article/pii/S221112472301567X
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporary Knockdown of p53 During Focal Limb Irradiation Increases the Development of Sarcomas
    1
    1. scibot 07 Dec 2023
      RRID:AB_297813

      DOI: 10.1158/2767-9764.CRC-23-0104

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    ncbi.nlm.nih.gov/pmc/articles/PMC10697056/
  15. Nov 2023
  16. www.mdpi.com www.mdpi.com
    The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence
    1
    1. scibot 17 Nov 2023
      RRID:AB_297813

      DOI: 10.3390/biomedicines11113017

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    mdpi.com/2227-9059/11/11/3017
  17. Aug 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes
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    1. scibot 19 Aug 2023
      RRID:AB_297813

      DOI: 10.1158/1078-0432.CCR-22-3156

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    ncbi.nlm.nih.gov/pmc/articles/PMC10425726/
  19. Oct 2022
  20. www.sciencedirect.com www.sciencedirect.com
    DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation
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    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111526

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    sciencedirect.com/science/article/pii/S2211124722013821
  21. Jun 2022
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    Microscopy-based single-cell proteomic profiling reveals heterogeneity in DNA damage response dynamics
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.crmeth.2022.100237

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    sciencedirect.com/science/article/pii/S2667237522001060
  23. May 2022
  24. academic.oup.com academic.oup.com
    Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells
    1
    1. scibot 26 May 2022
      RRID:AB_297813

      DOI: 10.1093/humrep/deac112

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    academic.oup.com/humrep/advance-article/doi/10.1093/humrep/deac112/6590738
  25. Mar 2022
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    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.molcel.2022.01.020

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    sciencedirect.com/science/article/pii/S1097276522000855
  27. Oct 2021
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    Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development
    1
    1. scibot 06 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109787

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    sciencedirect.com/science/article/pii/S2211124721012468
  29. Sep 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion
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      DOI: 10.1016/j.cell.2021.08.035

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    sciencedirect.com/science/article/pii/S0092867421010461
  31. www.sciencedirect.com www.sciencedirect.com
    The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
    1
    1. scibot 16 Sep 2021
      RRID:AB_297813

      DOI: 10.1016/j.celrep.2021.109694

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    sciencedirect.com/science/article/pii/S2211124721011414
  32. Mar 2021
  33. www.sciencedirect.com www.sciencedirect.com
    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
    1
    1. scibot 17 Mar 2021
      RRID:AB_297813

      DOI: 10.1016/j.celrep.2021.108840

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    sciencedirect.com/science/article/pii/S2211124721001546
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    The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks
    1
    1. scibot 08 Mar 2021
      RRID:AB_297813

      DOI: 10.1016/j.molcel.2020.10.009

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    sciencedirect.com/science/article/pii/S1097276520306924
  35. Sep 2020
  36. elifesciences.org elifesciences.org
    Parvovirus Minute Virus of Mice Interacts with Sites of Cellular DNA Damage to Establish and Amplify its Lytic Infection
    1
    1. scibot 23 Sep 2020
      RRID:AB_297813

      DOI: 10.7554/eLife.37750

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    elifesciences.org/articles/37750
  37. www.sciencedirect.com www.sciencedirect.com
    Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis
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    1. scibot 23 Sep 2020
      RRID:AB_297813

      DOI: 10.1016/j.celrep.2020.108021

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    sciencedirect.com/science/article/pii/S2211124720310068
  38. www.sciencedirect.com www.sciencedirect.com
    MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells
    1
    1. scibot 15 Sep 2020
      RRID:AB_297813

      DOI: 10.1016/j.devcel.2020.01.010

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    sciencedirect.com/science/article/pii/S1534580720300113
  39. elifesciences.org elifesciences.org
    HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137
    1
    1. scibot 03 Sep 2020
      anti-gamma H2AX phosphor S139

      DOI: 10.7554/eLife.55806

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    elifesciences.org/articles/55806
  40. Jan 2020
  41. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization
    1
    1. scibot 13 Jan 2020
      RRID:AB_297813

      DOI: 10.1016/j.celrep.2019.05.038

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    sciencedirect.com/science/article/pii/S2211124719306588
  42. www.sciencedirect.com www.sciencedirect.com
    GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability
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    1. scibot 13 Jan 2020
      RRID:AB_297813

      DOI: 10.1016/j.devcel.2019.11.006

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    sciencedirect.com/science/article/pii/S1534580719309372
  43. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_297813

      DOI: 10.1016/j.celrep.2019.02.047

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    sciencedirect.com/science/article/pii/S2211124719302189
  44. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of Meiotic Chromatin Architecture during Spermatogenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_297813

      DOI: 10.1016/j.molcel.2018.11.019

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    sciencedirect.com/science/article/pii/S1097276518309894
  45. www.sciencedirect.com www.sciencedirect.com
    Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
    1
    1. scibot 12 Jan 2020
      RRID:AB_297813

      DOI: 10.1016/j.cmet.2019.01.021

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    sciencedirect.com/science/article/pii/S155041311930021X
  46. Nov 2018
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6095691/
  48. www.sciencedirect.com www.sciencedirect.com
    iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610817304129
  49. www.sciencedirect.com www.sciencedirect.com
    Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
    1
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    sciencedirect.com/science/article/pii/S1097276517308808
  50. academic.oup.com academic.oup.com
    Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response
    1
    1. scibot 05 Nov 2018
      AB_297813

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    academic.oup.com/endo/article/158/11/4000/4093568
  51. Nov 2017
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells
    1
    1. scibot 08 Nov 2017
      AB_297813

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5345931/