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Multimodal spatial transcriptomics redefines cortical pathology in Huntington’s disease

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.cell.2026.09.064
  
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sciencedirect.com/science/article/pii/S0092867426012109
Sep 2026
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Nuclear body assembly by a viral repeat RNA promotes Kaposi’s sarcoma-associated herpesvirus gene expression

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1. scibot 18 Sep 2026
  
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  DOI: 10.1016/j.molcel.2026.08.022
  
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sciencedirect.com/science/article/pii/S1097276526005915
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5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia

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1. scibot 16 Sep 2026
  
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  DOI: 10.1016/j.molcel.2026.08.018
  
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sciencedirect.com/science/article/pii/S1097276526005873
Jul 2026
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Condensates of the chromatin regulator ANKRD11 restrict hypertranscribed genes to safeguard development

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1. scibot 23 Jul 2026
  
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  DOI: 10.1016/j.cell.2026.07.006
  
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sciencedirect.com/science/article/pii/S0092867426008044
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SUDS3 nuclear condensates decelerate DNA replication and safeguard genome stability

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1. scibot 20 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117713
  
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sciencedirect.com/science/article/pii/S2211124726007916
Jun 2026
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Nuclear proteome reveals microtubule-associated protein regulating fate and disease

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.cell.2026.05.019
  
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sciencedirect.com/science/article/pii/S0092867426005787
Mar 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226005705-main-html.html

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1. scibot 03 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115195
  
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54.241.53.176/158c9052c5efb4b495528944c8e6c2ea20652d01/1-s2.0-S2589004226005705-main-html.html
Feb 2026
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Cytoplasmic mRNA decay by the antiviral nuclease RNase L promotes transcriptional repression

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.117028
  
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sciencedirect.com/science/article/pii/S2211124726001063
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.molcel.2025.11.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12709618/
Nov 2025
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Disparate leukemia mutations converge on nuclear phase-separated condensates

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  DOI: 10.1016/j.cell.2025.10.010
  
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sciencedirect.com/science/article/pii/S0092867425011493
Oct 2025
rupress.org rupress.org

A heterozygous USB1 variant linked to immunodeficiency

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1. scibot 30 Oct 2025
  
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  DOI: 10.70962/jhi.20250110
  
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rupress.org/jhi/article/1/4/e20250110/278387/A-heterozygous-USB1-variant-linked-to
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Control of Inflammatory Response by Tissue Microenvironment

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1. scibot 24 Sep 2025
  
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  DOI: 10.1101/2024.05.10.592432
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11118380/
52.53.155.43 52.53.155.43

chu-et-al-2025-nuclear-paxillin-functions-as-a-molecular-switch-for-alternative-splicing-in-neurons-during-a-critical-html.html

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1. scibot 18 Sep 2025
  
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  DOI: 10.1038/s44318-025-00560-8
  
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52.53.155.43/5816f8d51d685993cdf7551f8a2c908df4a8c89b/chu-et-al-2025-nuclear-paxillin-functions-as-a-molecular-switch-for-alternative-splicing-in-neurons-during-a-critical-html.html
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Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.molcel.2025.08.014
  
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sciencedirect.com/science/article/pii/S1097276525006641
Aug 2025
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Protocol for the spatiotemporal profiling of RNA within nuclear compartments in human cell lines using SLAM-RT&Tag

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1. scibot 14 Aug 2025
  
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  DOI: 10.1016/j.xpro.2025.104017
  
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sciencedirect.com/science/article/pii/S266616672500423X
Jul 2025
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Multimodal CRISPR screens uncover DDX39B as a global repressor of A-to-I RNA editing

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116009
  
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sciencedirect.com/science/article/pii/S2211124725007806
Apr 2025
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A nuclear RNA degradation code is recognized by PAXT for eukaryotic transcriptome surveillance

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.03.010
  
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sciencedirect.com/science/article/pii/S1097276525002035
Mar 2025
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Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag

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1. scibot 13 Mar 2025
  
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  DOI: 10.1016/j.molcel.2025.02.012
  
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sciencedirect.com/science/article/pii/S1097276525001431
Jan 2025
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RBBP6 anchors pre-mRNA 3′ end processing to nuclear speckles for efficient gene expression

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.molcel.2024.12.016
  
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sciencedirect.com/science/article/pii/S1097276524010335
Dec 2024
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Proteolethargy is a pathogenic mechanism in chronic disease

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.10.051
  
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sciencedirect.com/science/article/pii/S0092867424012741
Sep 2024
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Large-scale map of RNA-binding protein interactomes across the mRNA life cycle

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.030
  
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sciencedirect.com/science/article/pii/S1097276524007263
Aug 2024
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Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.neuron.2024.07.025
  
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sciencedirect.com/science/article/pii/S0896627324005701
www.embopress.org www.embopress.org

LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis

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1. scibot 02 Aug 2024
  
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  ab11826
  
  DOI: 10.15252/embr.202051289
  
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embopress.org/doi/full/10.15252/embr.202051289
Apr 2024
www.cell.com www.cell.com

Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.stem.2024.03.015
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(24)00096-1
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An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains

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1. scibot 10 Apr 2024
  
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  DOI: 10.1016/j.molcel.2024.03.015
  
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sciencedirect.com/science/article/pii/S1097276524002259
Mar 2024
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Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113941
  
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sciencedirect.com/science/article/pii/S2211124724002699
Jan 2024
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The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.celrep.2023.113651
  
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sciencedirect.com/science/article/pii/S2211124723016625
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CHTOP Alleviates Cerebral Ischemia/Reperfusion-Induced Injury by Regulating RNA Alternative Splicing

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1. scibot 10 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108688
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770728/
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Direct observation of a condensate effect on super-enhancer controlled gene bursting

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1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.12.005
  
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sciencedirect.com/science/article/pii/S0092867423013375
Dec 2023
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Nucleolus activity-dependent recruitment and biomolecular condensation by pH sensing

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  DOI: 10.1016/j.molcel.2023.10.031
  
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sciencedirect.com/science/article/pii/S1097276523008687
Nov 2023
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Targeted perturbation of signaling-driven condensates

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.molcel.2023.10.023
  
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sciencedirect.com/science/article/pii/S1097276523008602
Sep 2023
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TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113177
  
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sciencedirect.com/science/article/pii/S2211124723011890
Aug 2023
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Senescent cells form nuclear foci that contain the 26S proteasome

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1. scibot 04 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112880
  
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sciencedirect.com/science/article/pii/S2211124723008914
May 2023
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Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.celrep.2022.111086
  
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sciencedirect.com/science/article/pii/S2211124722008889
Sep 2022
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SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.molcel.2022.08.031
  
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sciencedirect.com/science/article/pii/S1097276522008516
Aug 2022
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Disruption of nuclear envelope integrity as a possible initiating event in tauopathies

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1. scibot 26 Aug 2022
  
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  RRID:AB_298608
  
  DOI: 10.1016/j.celrep.2022.111249
  
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sciencedirect.com/science/article/pii/S2211124722010671
Jun 2022
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A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission

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1. scibot 17 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104536
  
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Sep 2021
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Identification of abscission checkpoint bodies as structures that regulate ESCRT factors to control abscission timing

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  DOI: 10.7554/eLife.63743
  
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Aug 2021
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Untitled document

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  DOI: 10.1016/j.cell.2018.10.057
  
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Untitled document

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  DOI: 10.1016/j.cell.2017.05.029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5473940/
May 2021
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N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

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1. scibot 28 May 2021
  
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  DOI: 10.1016/j.ccell.2021.04.017
  
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p53 mediates target gene association with nuclear speckles for amplified RNA expression

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  DOI: 10.1016/j.molcel.2021.03.006
  
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sciencedirect.com/science/article/pii/S109727652100174X
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Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin

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  DOI: 10.1016/j.cell.2020.07.032
  
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Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS

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1. scibot 14 Apr 2021
  
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  DOI: 10.1016/j.molcel.2021.02.033
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
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Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components

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1. scibot 13 Apr 2021
  
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  DOI: 10.1016/j.neuron.2021.03.026
  
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Mar 2021
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MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

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Sep 2020
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RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases

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  DOI: 10.1186/s40478-020-00965-y
  
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link.springer.com/article/10.1186/s40478-020-00965-y
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Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation

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  DOI: 10.1016/j.molcel.2020.01.025
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30046-0
Jan 2020
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Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability

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  DOI: 10.1016/j.celrep.2019.07.010
  
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sciencedirect.com/science/article/pii/S2211124719309003
Nov 2018
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Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments

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1. scibot 05 Nov 2018
  
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High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

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Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

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Dynamics and Spatial Genomics of the Nascent Transcriptome by Intron seqFISH

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sciencedirect.com/science/article/pii/S0092867418306470
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Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518301345
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Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP.

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5619949/
Nov 2017
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SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs

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