120 Matching Annotations
  1. Last 7 days
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    The extracellular matrix integrates mitochondrial homeostasis
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    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S009286742400638X
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    Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
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      DOI: 10.1242/dmm.043174

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    ncbi.nlm.nih.gov/pmc/articles/PMC7328144/
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    Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End
    2
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      DOI: 10.1016/j.devcel.2020.02.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC7170007/
  5. Jul 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation
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    sciencedirect.com/science/article/pii/S258900422401410X
  7. Jun 2024
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    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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    sciencedirect.com/science/article/pii/S0092867424005269
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    TRABD modulates mitochondrial homeostasis and tissue integrity
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    sciencedirect.com/science/article/pii/S2211124724006326
  10. Apr 2024
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    Multi-omic profiling reveals the endogenous and neoplastic responses to immunotherapies in cutaneous T cell lymphoma
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    sciencedirect.com/science/article/pii/S2666379124001964
  12. Mar 2024
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    Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway
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    sciencedirect.com/science/article/pii/S1534580724001424
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C17orf80 binds the mitochondrial genome to promote its replication
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      DOI: 10.1083/jcb.202302037

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    ncbi.nlm.nih.gov/pmc/articles/PMC10484793/
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    OPA1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1
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    sciencedirect.com/science/article/pii/S2589004224003857
  16. Feb 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mtDNA extramitochondrial replication mediates mitochondrial defect effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844862/
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    Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding
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    1. scibot 08 Feb 2024
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    sciencedirect.com/science/article/pii/S155041312400007X
  19. Jan 2024
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    Inosine induces stemness features in CAR-T cells and enhances potency
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    1. scibot 26 Jan 2024
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    sciencedirect.com/science/article/pii/S1535610824000084
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    Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation
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    1. scibot 25 Jan 2024
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    sciencedirect.com/science/article/pii/S1097276524000030
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    Partial loss of MCU mitigates pathology in vivo across a diverse range of neurodegenerative disease models
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    sciencedirect.com/science/article/pii/S2211124724000093
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    Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
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      DOI: 10.1016/j.cell.2023.12.010

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    sciencedirect.com/science/article/pii/S0092867423013429
  24. Oct 2023
  25. www.tandfonline.com www.tandfonline.com
    Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders
    1
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      DOI: 10.1080/21678421.2023.2261979

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    tandfonline.com/doi/abs/10.1080/21678421.2023.2261979
  26. Aug 2023
  27. www.sciencedirect.com www.sciencedirect.com
    PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development
    1
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      DOI: 10.1016/j.cell.2023.08.008

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    sciencedirect.com/science/article/abs/pii/S0092867423008620
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo
    1
    1. scibot 19 Aug 2023
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      DOI: 10.1371/journal.pbio.3002244

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    ncbi.nlm.nih.gov/pmc/articles/PMC10427020/
  29. Jul 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage
    1
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      DOI: 10.1371/journal.pgen.1010828

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    ncbi.nlm.nih.gov/pmc/articles/PMC10368295/
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    PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics
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      DOI: 10.1016/j.celrep.2023.112895

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    sciencedirect.com/science/article/pii/S2211124723009063
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    Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation
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      DOI: 10.1016/j.isci.2023.107180

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    sciencedirect.com/science/article/pii/S2589004223012579
  33. Jun 2023
  34. www.nature.com www.nature.com
    Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
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      DOI: 10.1038/s41596-023-00831-w

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    nature.com/articles/s41596-023-00831-w
  35. May 2023
  36. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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    sciencedirect.com/science/article/pii/S1097276523003350
  37. Apr 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles
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      DOI: 10.1016/j.cmet.2023.03.016

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    sciencedirect.com/science/article/pii/S1550413123000943
  39. Mar 2023
  40. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Switching ubiquitous and muscle-specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine-tunes complex IV activity
    1
    1. scibot 29 Mar 2023
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      DOI: 10.1096/fj.202201223RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201223RR
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    Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest
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    sciencedirect.com/science/article/pii/S2211124723002267
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    Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
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      DOI: 10.1016/j.neuron.2023.02.019

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    sciencedirect.com/science/article/pii/S089662732300123X
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency
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      DOI: 10.7554/eLife.68047

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    ncbi.nlm.nih.gov/pmc/articles/PMC9991045/
  44. Feb 2023
  45. elifesciences.org elifesciences.org
    Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14)
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      DOI: 10.7554/eLife.82555

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    elifesciences.org/articles/82555
  46. Dec 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy
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    sciencedirect.com/science/article/pii/S2211124722016345
  48. www.sciencedirect.com www.sciencedirect.com
    GABA regulates IL-1β production in macrophages
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    sciencedirect.com/science/article/pii/S2211124722016539
  49. Oct 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Spatial epitope barcoding reveals clonal tumor patch behaviors
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    sciencedirect.com/science/article/pii/S1535610822004433
  51. Sep 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux
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    ncbi.nlm.nih.gov/pmc/articles/PMC9468384/
  53. Aug 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity
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      DOI: 10.1016/j.ebiom.2022.104192

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    sciencedirect.com/science/article/pii/S2352396422003735
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
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      DOI: 10.1016/j.cell.2022.06.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC9531054/
  56. Jun 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation
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    sciencedirect.com/science/article/pii/S2589004222008549
  58. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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      DOI: 10.1016/j.molcel.2022.06.005

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    sciencedirect.com/science/article/pii/S109727652200541X
  59. europepmc.org europepmc.org
    Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia
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      DOI: 10.3389/fcell.2022.788516

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    Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia
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  61. May 2022
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    Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation
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  63. Mar 2022
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    Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models
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    Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains
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    Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy
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    Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease
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  68. Feb 2022
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    Mitochondrial Localization of CB1 in Progesterone-producing Cells of Ovarian Interstitial Glands of Adult Mice - Anussara Kamnate, Juthathip Sirisin, Masahiko Watanabe, Hisatake Kondo, Wiphawi Hipkaeo, Surang Chomphoo, 2021
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  70. Dec 2021
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    Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress
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  73. Nov 2021
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    A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
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  75. Oct 2021
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    Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing
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    Glutamate metabolism directs energetic trade-offs to shape host-pathogen susceptibility in Drosophila
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  78. Sep 2021
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    Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival
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  81. Aug 2021
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    Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation
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  85. Jul 2021
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    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells
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    Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila
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    Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase
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  94. May 2021
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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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    Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism
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  97. Apr 2021
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    Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth
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    Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output
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    Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis
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    Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress
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    A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients
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    Comparative analysis of CI- and CIV-containing respiratory supercomplexes at single-cell resolution
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  106. Feb 2021
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    PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers
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    Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species‐mediated mitochondrial injury
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  109. Jan 2021
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    Ecd promotes U5 snRNP maturation and Prp8 stability
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  111. Nov 2020
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    Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes
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    Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End
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  118. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Protocol for the Analysis of Yeast and Human Mitochondrial Respiratory Chain Complexes and Supercomplexes by Blue Native Electrophoresis
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  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I
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    Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
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  123. www.nature.com www.nature.com
    The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models
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  124. Jan 2020
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    Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila
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    Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A
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  128. elifesciences.org elifesciences.org
    Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repressive Gene Regulation Synchronizes Development with Cellular Metabolism
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    A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production
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    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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  133. www.sciencedirect.com www.sciencedirect.com
    Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance
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    The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria
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  137. Nov 2018
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    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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    Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
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    PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions
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  144. Nov 2017
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    Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration
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    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
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    A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers
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    A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I–III
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    In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation
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    Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
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