104 Matching Annotations
  1. Last 7 days
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    Live-cell imaging of RNA Pol II and elongation factors distinguishes competing mechanisms of transcription regulation
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    1. scibot 20 Aug 2024
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    sciencedirect.com/science/article/pii/S1097276524005859
  3. Jul 2024
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    Mechanomemory of nucleoplasm and RNA polymerase II after chromatin stretching by a microinjected magnetic nanoparticle force
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    sciencedirect.com/science/article/pii/S2211124724007915
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    DNA break induces rapid transcription repression mediated by proteasome-dependent RNAPII removal
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    sciencedirect.com/science/article/pii/S2211124724007496
  6. Jun 2024
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    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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      DOI: 10.1126/sciadv.adn7732

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    science.org/doi/10.1126/sciadv.adn7732
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11135424/
  9. Apr 2024
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    DDX21 mediates co-transcriptional RNA m6A modification to promote transcription termination and genome stability
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    sciencedirect.com/science/article/pii/S1097276524001886
  11. Mar 2024
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    RNAP II antagonizes mitotic chromatin folding and chromosome segregation by condensin
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    sciencedirect.com/science/article/pii/S2211124724002298
  13. Feb 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
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      DOI: 10.1038/s41467-024-45760-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10873513/
  15. Dec 2023
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    Collisions of RNA polymerases behind the replication fork promote alternative RNA splicing in newly replicated chromatin
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    sciencedirect.com/science/article/pii/S1097276523010122
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    Asymmetrical nucleosomal DNA signatures regulate transcriptional directionality
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    sciencedirect.com/science/article/pii/S2211124723016170
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    A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells
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      DOI: 10.1016/j.chembiol.2023.11.009

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    sciencedirect.com/science/article/pii/S2451945623004245
  19. Nov 2023
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    Targeted perturbation of signaling-driven condensates
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    sciencedirect.com/science/article/pii/S1097276523008602
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
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    Human histone H1 variants impact splicing outcome by controlling RNA polymerase II elongation
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    sciencedirect.com/science/article/pii/S1097276523008067
  23. Jun 2023
  24. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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      DOI: 10.15252/embr.202256492

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    embopress.org/doi/10.15252/embr.202256492
  25. Apr 2023
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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      DOI: 10.1016/j.celrep.2023.112341

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    sciencedirect.com/science/article/pii/S2211124723003522
  27. Jan 2023
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    EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release
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      DOI: 10.1016/j.celrep.2022.111830

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    sciencedirect.com/science/article/pii/S2211124722017223
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    MDC1 maintains active elongation complexes of RNA polymerase II
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      DOI: 10.1016/j.celrep.2022.111979

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    sciencedirect.com/science/article/pii/S2211124722018836
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    Distinct patterns of RNA polymerase II and transcriptional elongation characterize mammalian genome activation
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      DOI: 10.1016/j.celrep.2022.111865

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    sciencedirect.com/science/article/pii/S2211124722017612
  31. Nov 2022
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    SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy
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    sciencedirect.com/science/article/pii/S2211124722015765
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    Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization
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    sciencedirect.com/science/article/pii/S2211124722014371
  34. Oct 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer
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      DOI: 10.1016/j.molcel.2022.09.034

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    sciencedirect.com/science/article/pii/S1097276522009558
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures
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      DOI: 10.1016/j.isci.2022.105200

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550643/
  37. Sep 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Confined migration induces heterochromatin formation and alters chromatin accessibility
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      DOI: 10.1016/j.isci.2022.104978

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    ncbi.nlm.nih.gov/pmc/articles/PMC9474860/
  39. May 2022
  40. www.sciencedirect.com www.sciencedirect.com
    DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production
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      DOI: 10.1016/j.molcel.2022.04.030

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    sciencedirect.com/science/article/pii/S1097276522003938
  41. Mar 2022
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    The PAF1 complex promotes 3′ processing of pervasive transcripts
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      DOI: 10.1016/j.celrep.2022.110519

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    sciencedirect.com/science/article/pii/S2211124722002558
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    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276522001186
  44. Feb 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Activation-induced chromatin reorganization in neurons depends on HDAC1 activity
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      DOI: 10.1016/j.celrep.2022.110352

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    sciencedirect.com/science/article/pii/S2211124722000687
  46. Jan 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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      DOI: 10.1016/j.devcel.2021.12.019

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    sciencedirect.com/science/article/pii/S153458072101039X
  48. Nov 2021
  49. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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      DOI: 10.1016/j.molcel.2021.11.002

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  50. Oct 2021
  51. www.sciencedirect.com www.sciencedirect.com
    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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    sciencedirect.com/science/article/pii/S1097276521007504
  52. Aug 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.neuron.2017.04.022

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    ncbi.nlm.nih.gov/pmc/articles/PMC5508517/
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    ncbi.nlm.nih.gov/pmc/articles/PMC6344342/
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    sciencedirect.com/science/article/pii/S0960982218314167
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      DOI: 10.7554/eLife.13087

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    ncbi.nlm.nih.gov/pmc/articles/PMC4951197/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6303189/
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    elifesciences.org/articles/13087
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    C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing
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    sciencedirect.com/science/article/pii/S2211124718316905
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      DOI: 10.1016/j.molcel.2019.01.033

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  61. Jul 2021
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    The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory
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    C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing
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    Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
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    The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
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    The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages
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    Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency
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