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123 Matching Annotations

Aug 2025
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A fungal chromatin remodeler drives transcription by establishing an open chromatin architecture and activated histone environment

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116169
  
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sciencedirect.com/science/article/pii/S2211124725009404
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint

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1. scibot 10 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.115966
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12330366/
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Hypoxia-induced genome-wide DNA demethylation by DNMT3A and EMT of cancer cells

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1. scibot 08 Aug 2025
  
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  DOI: 10.1186/s11658-025-00775-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12326847/
Jul 2025
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The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115966
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12330366/
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The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis

1
1. scibot 09 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.019
  
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sciencedirect.com/science/article/pii/S1534580725003740
Jun 2025
52.53.155.43 52.53.155.43

PDF-html.html

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  DOI: 10.1158/1535-7163.mct-24-0693
  
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52.53.155.43/8255bf0e683c73f50dd41b49b5f6c81a8e58d07f/PDF-html.html
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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

1
1. scibot 12 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112750
  
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sciencedirect.com/science/article/pii/S2589004225010119
Feb 2025
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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115273
  
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sciencedirect.com/science/article/pii/S2211124725000440
Jan 2025
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Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis

1
1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2025.101928
  
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sciencedirect.com/science/article/pii/S2666379125000011
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells

1
1. scibot 05 Dec 2024
  
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  DOI: 10.1038/s44318-024-00276-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11612440/
Sep 2024
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Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ebiom.2020.102694
  
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sciencedirect.com/science/article/pii/S2352396420300694
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Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor

1
1. scibot 25 Sep 2024
  
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  RRID:AB_1977539
  
  DOI: 10.1016/j.celrep.2019.10.012
  
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sciencedirect.com/science/article/pii/S2211124719313129
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PICKLE-mediated nucleosome condensing drives H3K27me3 spreading for the inheritance of Polycomb memory during differentiation

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.018
  
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sciencedirect.com/science/article/pii/S1097276524006920
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification

1
1. scibot 23 Aug 2024
  
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  DOI: 10.7554/eLife.96216
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11333042/
Jul 2024
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Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.molcel.2024.06.022
  
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sciencedirect.com/science/article/pii/S109727652400529X
Jun 2024
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Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity

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1. scibot 14 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11167441/
Apr 2024
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SAFB restricts contact domain boundaries associated with L1 chimeric transcription

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1. scibot 11 Apr 2024
  
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  DOI: 10.1016/j.molcel.2024.03.021
  
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sciencedirect.com/science/article/pii/S1097276524002314
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Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.ccell.2024.03.005
  
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sciencedirect.com/science/article/pii/S1535610824000904
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Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

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1. scibot 04 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.020
  
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sciencedirect.com/science/article/pii/S1534580724001886
Mar 2024
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Deficiency of lncRNA MERRICAL abrogates macrophage chemotaxis and diabetes-associated atherosclerosis

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1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113815
  
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sciencedirect.com/science/article/pii/S2211124724001438
Feb 2024
www.cell.com www.cell.com

Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma

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1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.cmet.2024.01.018
  
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cell.com/cell-metabolism/abstract/S1550-4131(24)00018-4
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Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons

3
1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.neuron.2024.01.023
  
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  DOI: 10.1016/j.neuron.2024.01.023
  
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  DOI: 10.1016/j.neuron.2024.01.023
  
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sciencedirect.com/science/article/pii/S0896627324000497
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The BAS chromatin remodeler determines brassinosteroid-induced transcriptional activation and plant growth in Arabidopsis

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1. scibot 15 Feb 2024
  
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  DOI: 10.1016/j.devcel.2024.01.021
  
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sciencedirect.com/science/article/pii/S1534580724000418
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SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability

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  DOI: 10.1016/j.celrep.2024.113778
  
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sciencedirect.com/science/article/pii/S2211124724001062
Dec 2023
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Nano-CUT&Tag for multimodal chromatin profiling at single-cell resolution

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1. scibot 29 Dec 2023
  
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  DOI: 10.1038/s41596-023-00932-6
  
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nature.com/articles/s41596-023-00932-6
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Crosstalk between chromatin and Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage

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  DOI: 10.1016/j.isci.2023.108624
  
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sciencedirect.com/science/article/pii/S2589004223027013
Oct 2023
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Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming

1
1. scibot 09 Oct 2023
  
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  DOI: 10.7554/eLife.85365
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10558205/
Jun 2023
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Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression

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1. scibot 16 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112587
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10592478/
May 2023
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Chemical-induced epigenome resetting for regeneration program activation in human cells

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1. scibot 24 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112547
  
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sciencedirect.com/science/article/pii/S2211124723005582
Apr 2023
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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

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  DOI: 10.1016/j.molcel.2023.02.007
  
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sciencedirect.com/science/article/pii/S1097276523001028
Mar 2023
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TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

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1. scibot 22 Mar 2023
  
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  DOI: 10.1016/j.jbc.2023.104621
  
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sciencedirect.com/science/article/pii/S0021925823002636
www.biorxiv.org www.biorxiv.org

Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming

1
1. scibot 08 Mar 2023
  
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  DOI: 10.1101/2023.01.15.524137
  
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biorxiv.org/content/10.1101/2023.01.15.524137v1
Nov 2022
52.53.155.43 52.53.155.43

Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes promotes chromatin compaction at promoters

1
1. scibot 03 Nov 2022
  
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  DOI: 10.21203/rs.3.rs-1992778/v1
  
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52.53.155.43/2bd54e9365bad522cb4a8b476de43c7b8e5f1883/33e3335b-b6e5-4d66-a51d-edb70848662b-html.html
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes

1
1. scibot 04 Oct 2022
  
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  AB_305237
  
  DOI: 10.1016/j.isci.2022.105135
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9523354/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector

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1. scibot 01 Oct 2022
  
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Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity

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Androgen-mediated perturbation of the hepatic circadian system through epigenetic modulation promotes NAFLD in PCOS mice

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Aberrant Epigenetic Alteration of PAX1 Expression Contributes to Parathyroid Tumorigenesis

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The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms

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mTORC1 is required for epigenetic silencing during β-cell functional maturation

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HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution

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Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes

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Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction

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Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor

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ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

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Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors

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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

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Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease

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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

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Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity

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Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life

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Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells

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The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity

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Establishment, maintenance, and recall of inflammatory memory

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GCM2 Silencing in Parathyroid Adenoma is associated with Promoter Hypermethylation and Gain of Methylation on Histone 3

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Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons

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Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity

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Retinoid X Receptor Activation Alters the Chromatin Landscape To Commit Mesenchymal Stem Cells to the Adipose Lineage

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Vernalization-Triggered Intragenic Chromatin Loop Formation by Long Noncoding RNAs

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Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

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Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

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Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction

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Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability

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B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells

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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

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Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation

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H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model

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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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Integrated multi-omics reveal epigenomic disturbance of assisted reproductive technologies in human offspring

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Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells

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The Hox Transcription Factor Ubx Ensures Somatic Myogenesis by Suppressing the Mesodermal Master Regulator Twist

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G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

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Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma

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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury

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Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism

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DGCR8/ZFAT-AS1 promotes CDX2 transcription in a PRC2 complex dependent manner to facilitate the malignant biological behavior of glioma cells

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The Dm-Myb Oncoprotein Contributes to Insulator Function and Stabilizes Repressive H3K27me3 PcG Domains

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Oct4-Mediated Inhibition of Lsd1 Activity Promotes the Active and Primed State of Pluripotency Enhancers

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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

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H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammation

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Generation of four iPSC lines from two siblings with a microdeletion at the CNTN6 gene and intellectual disability

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lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

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Temporal Control of the TGF-β Signaling Network by Mouse ESC MicroRNA Targets of Different Affinities

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The histone demethylase KDM6B in the medial prefrontal cortex epigenetically regulates cocaine reward memory

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Polymer Modeling Predicts Chromosome Reorganization in Senescence

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DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse

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Untitled document

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Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

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POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication

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Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming

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Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT

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academic.oup.com/endo/article/159/4/1595/4841949
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TERT‐EZH2 network regulates lipid metabolism and DNA damage responses in glioblastoma

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onlinelibrary.wiley.com/doi/10.1111/jnc.14152/full
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Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia

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Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase

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Epigenetic Effects of an Adenosine Derivative in a Wistar Rat Model of Liver Cirrhosis

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Loss of TET1 facilitates DLD1 colon cancer cell migration via H3K27me3‐mediated down‐regulation of E‐cadherin

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Sam68 Allows Selective Targeting of Human Cancer Stem Cells

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Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8+ T Cell Terminal Differentiation and Loss of Multipotency

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A Metabolic Function for Phospholipid and Histone Methylation

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PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs

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Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

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