63 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells
    1
    1. scibot 13 Jun 2024
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2024.114047

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    ncbi.nlm.nih.gov/pmc/articles/PMC11164428/
  3. www.sciencedirect.com www.sciencedirect.com
    Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109929

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    sciencedirect.com/science/article/pii/S2589004224011519
  4. Nov 2023
  5. www.sciencedirect.com www.sciencedirect.com
    GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function
    1
    1. scibot 02 Nov 2023
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2023.113326

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    sciencedirect.com/science/article/pii/S2211124723013384
  6. Oct 2023
  7. elifesciences.org elifesciences.org
    Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
    1
    1. scibot 14 Oct 2023
      RRID:AB_306130

      DOI: 10.7554/eLife.85056

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    elifesciences.org/articles/85056
  8. Aug 2023
  9. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
    2
    1. scibot 18 Aug 2023
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2023.112914

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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    52.53.155.43/464fcb14db36fa0ad68672734eea21dbff7f105c/PIIS2211124723009257-html.html
  10. Jun 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
    1
    1. scibot 21 Jun 2023
      RRID:AB_306130

      DOI: 10.1016/j.cmet.2023.05.007

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    sciencedirect.com/science/article/pii/S1550413123001845
  12. May 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Zhx2 maintains islet β cell mass and function by transcriptionally regulating Pax6
    1
    1. scibot 26 May 2023
      AB_306130

      DOI: 10.1016/j.isci.2023.106871

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    sciencedirect.com/science/article/pii/S2589004223009483
  14. Mar 2023
  15. europepmc.org europepmc.org
    β-Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control
    1
    1. scibot 29 Mar 2023
      RRID:AB_306130

      DOI: 10.1111/1753-0407.13380

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    europepmc.org/article/med/36942376
  16. Feb 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of IAPP suppression in mouse and human islets by GLP-1 analogue conjugated antisense oligonucleotide
    1
    1. scibot 23 Feb 2023
      RRID:AB_306130

      DOI: 10.3389/fmolb.2023.1096286

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    ncbi.nlm.nih.gov/pmc/articles/PMC9939749/
  18. Jan 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation couples insulin hypersecretion with β cell failure in diabetes
    1
    1. scibot 13 Jan 2023
      RRID:AB_306130

      DOI: 10.1016/j.cmet.2022.12.012

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    sciencedirect.com/science/article/pii/S1550413122005496
  20. Dec 2022
  21. diabetesjournals.org diabetesjournals.org
    Dynamic Ins2 Gene Activity Defines β-cell Maturity States
    2
    1. scibot 09 Dec 2022
      AB_306130

      DOI: 10.2337/db21-1065

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    2. scibot 09 Dec 2022
      AB_30613

      DOI: 10.2337/db21-1065

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    diabetesjournals.org/diabetes/article/71/12/2612/147687/Dynamic-Ins2-Gene-Activity-Defines-Cell-Maturity
  22. Nov 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
    1
    1. scibot 03 Nov 2022
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2022.111581

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    sciencedirect.com/science/article/pii/S2211124722014462
  24. Oct 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using 111In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements
    1
    1. scibot 26 Oct 2022
      RRID:AB_306130

      DOI: 10.3389/fendo.2022.1010825

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    ncbi.nlm.nih.gov/pmc/articles/PMC9559817/
  26. www.sciencedirect.com www.sciencedirect.com
    E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
    1
    1. scibot 05 Oct 2022
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2022.111436

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    sciencedirect.com/science/article/pii/S2211124722012773
  27. Aug 2022
  28. academic.oup.com academic.oup.com
    Circulating 1,5-anhydroglucitol as a biomarker of ß-cell mass independent of a diabetes phenotype in human subjects
    1
    1. scibot 13 Aug 2022
      RRID:AB_306130

      DOI: 10.1210/clinem/dgac444

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac444/6648530
  29. www.sciencedirect.com www.sciencedirect.com
    mTORC1 is required for epigenetic silencing during β-cell functional maturation
    1
    1. scibot 10 Aug 2022
      RRID:AB_306130

      DOI: 10.1016/j.molmet.2022.101559

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    sciencedirect.com/science/article/pii/S2212877822001284
  30. Jun 2022
  31. 52.53.155.43 52.53.155.43
    Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER
    1
    1. scibot 25 Jun 2022
      RRID:AB_306130

      DOI: 10.1016/j.isci.2022.104603

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    52.53.155.43/5e8eccfbc0c47f7f56abdc84e3011c94ca63185a/1-s2.0-S2589004222008756-main-html.html
  32. Apr 2022
  33. academic.oup.com academic.oup.com
    Deletion of Gdf15 reduces ER stress-induced beta cell apoptosis and diabetes
    1
    1. scibot 27 Apr 2022
      RRID:AB_306130

      DOI: 10.1210/endocr/bqac030

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    academic.oup.com/endo/article/163/5/bqac030/6548945
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation
    1
    1. scibot 21 Apr 2022
      RRID:AB_306130

      DOI: 10.1016/j.devcel.2017.04.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC5425251/
  35. Aug 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes
    1
    1. scibot 25 Aug 2021
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2021.109613

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    sciencedirect.com/science/article/pii/S2211124721010512
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
    1
    1. scibot 14 Aug 2021
      RRID:AB_306130

      DOI: 10.1016/j.cmet.2018.12.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC6701710/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
    1
    1. scibot 11 Aug 2021
      RRID:AB_306130

      DOI: 10.1210/js.2017-00081

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    ncbi.nlm.nih.gov/pmc/articles/PMC5542010/
  39. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 01 Aug 2021
      RRID:AB_306130

      DOI: 10.1210/js.2017-00081

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    academic.oup.com/jes/article/1/5/385/3084588
  40. Jul 2021
  41. academic.oup.com academic.oup.com
    Increased Chromogranin A–Positive Hormone-Negative Cells in Chronic Pancreatitis
    1
    1. scibot 29 Jul 2021
      RRID:AB_306130

      DOI: 10.1210/jc.2017-01562

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    academic.oup.com/jcem/article/103/6/2126/4961057
  42. academic.oup.com academic.oup.com
    Effects of Linagliptin on Pancreatic α Cells of Type 1 Diabetic Mice
    1
    1. scibot 28 Jul 2021
      RRID:AB_306130

      DOI: 10.1210/js.2017-00253

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    academic.oup.com/jes/article/1/10/1224/4100164
  43. europepmc.org europepmc.org
    A MEN1 pancreatic neuroendocrine tumour mouse model under temporal control
    1
    1. scibot 28 Jul 2021
      AB_306130

      DOI: 10.1530/EC-17-0040

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    europepmc.org/articles/PMC5632719/
  44. academic.oup.com academic.oup.com
    Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy
    1
    1. scibot 28 Jul 2021
      RRID:AB_306130

      DOI: 10.1210/en.2017-00111

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    academic.oup.com/endo/article/158/8/2486/3860207/Mutant-Mice-With-Calcium-Sensing-Receptor
  45. Jun 2021
  46. academic.oup.com academic.oup.com
    CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice
    1
    1. scibot 29 Jun 2021
      RRID:AB_306130

      DOI: 10.1210/endocr/bqab064

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    academic.oup.com/endo/article/162/6/bqab064/6188411
  47. May 2021
  48. academic.oup.com academic.oup.com
    Pro-inflammatory Cytokine Interleukin 1β Disrupts β cell Circadian Clock Function and Regulation of Insulin Secretion
    1
    1. scibot 10 May 2021
      RRID:AB_306130

      DOI: 10.1210/endocr/bqaa084

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    academic.oup.com/endo/article/162/1/bqaa084/5846213
  49. academic.oup.com academic.oup.com
    Proper mTORC1 activity is required for glucose sensing and early adaptation in human pancreatic beta cell
    1
    1. scibot 10 May 2021
      RRID:AB_306130

      DOI: 10.1210/clinem/dgaa786

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    academic.oup.com/jcem/article/106/2/e562/5943203
  50. Apr 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes
    1
    1. scibot 19 Apr 2021
      RRID:AB_306130

      DOI: 10.1016/j.devcel.2021.02.011

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    sciencedirect.com/science/article/pii/S1534580721001222
  52. www.sciencedirect.com www.sciencedirect.com
    AQP8 is a crucial H2O2 transporter in insulin-producing RINm5F cells
    1
    1. scibot 02 Apr 2021
      Insulin

      DOI: 10.1016/j.redox.2021.101962

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    sciencedirect.com/science/article/pii/S2213231721001105
  53. Feb 2021
  54. academic.oup.com academic.oup.com
    Multiple Endocrine Neoplasia Type 1 (MEN1) phenocopy due to a cell cycle division 73 ( CDC73 ) variant
    1
    1. scibot 28 Feb 2021
      RRID:AB_306130

      DOI: 10.1210/jendso/bvaa142

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    academic.oup.com/jes/article/4/11/bvaa142/5911939
  55. Dec 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Autosomal Dominant Diabetes Associated with a Novel ZYG11A Mutation Resulting in Cell Cycle Arrest in Beta-Cells
    1
    1. scibot 20 Dec 2020
      anti-insulin

      DOI: 10.1016/j.mce.2020.111126

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    sciencedirect.com/science/article/pii/S0303720720304287
  57. Sep 2020
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes
    1
    1. scibot 26 Sep 2020
      RRID:AB_306130

      DOI: 10.1111/bph.15195

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15195
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Goldfish adipocytes are pancreatic beta cell‐like, glucose‐responsive insulin‐producing cells
    1
    1. scibot 12 Sep 2020
      RRID:AB_306130

      DOI: 10.1002/jcp.29581

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29581
  60. www.sciencedirect.com www.sciencedirect.com
    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
    1
    1. scibot 07 Sep 2020
      RRID:AB_306130

      DOI: 10.1016/j.devcel.2020.01.015

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    sciencedirect.com/science/article/pii/S1534580720300162
  61. www.sciencedirect.com www.sciencedirect.com
    Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion
    1
    1. scibot 06 Sep 2020
      RRID:AB_306130

      DOI: 10.1016/j.celrep.2020.107761

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    sciencedirect.com/science/article/pii/S2211124720307415
  62. academic.oup.com academic.oup.com
    Reduced expression of the co-regulator TLE1 in type 2 diabetes is associated with increased islet α-cell number
    1
    1. scibot 04 Sep 2020
      RRID:AB_306130

      DOI: 10.1210/endocr/bqaa011

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  63. Jan 2020
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    TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation
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      DOI: 10.1016/j.celrep.2019.07.035

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  65. academic.oup.com academic.oup.com
    Non-invasive evaluation of GPR119 agonist effects on β-cell mass in diabetic male mice using 111 In-exendin-4 SPECT/CT
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      DOI: 10.1210/en.2019-00556

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    Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake
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      DOI: 10.1016/j.cmet.2019.07.013

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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
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      DOI: 10.1016/j.cmet.2018.12.003

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  68. link.springer.com link.springer.com
    Pregnancy in human <Emphasis Type="Italic">IAPP</Emphasis> transgenic mice recapitulates beta cell stress in type 2 diabetes
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      DOI: 10.1007/s00125-019-4843-z

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  69. Nov 2018
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    Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes
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    Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals
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    Increased Chromogranin A–Positive Hormone-Negative Cells in Chronic Pancreatitis
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    Vitamin D Switches BAF Complexes to Protect β Cells
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    Isl1β Overexpression With Key β Cell Transcription Factors Enhances Glucose-Responsive Hepatic Insulin Production and Secretion
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    In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation
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  78. Nov 2017
  79. academic.oup.com academic.oup.com
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
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    Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis
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  82. www.sciencedirect.com www.sciencedirect.com
    Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation
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    The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice
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    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
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    In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming
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    A Single-Cell Transcriptome Atlas of the Human Pancreas
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