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  2. 52.53.155.43 52.53.155.43
    can-24-1611-html.html
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    3. scibot 19 Dec 2024
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    The mesenteric adipokine SFRP5 alleviated intestinal epithelial apoptosis improving barrier dysfunction in Crohn's disease
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    1. scibot 17 Dec 2024
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    sciencedirect.com/science/article/pii/S2589004224027445
  4. Dec 2024
  5. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 3CLpro (main protease) regulates caspase activation of gasdermin-D/E pores leading to secretion and extracellular activity of 3CLpro
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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
  7. Nov 2024
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overactive PKA signaling underlies the hyperalgesia in an ADHD mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539593/
  9. Oct 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Type I IFN drives unconventional IL-1β secretion in lupus monocytes
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    sciencedirect.com/science/article/pii/S1074761324004485
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    Activated sympathetic nerve post stroke downregulates Toll-like receptor 5 and disrupts the gut mucosal barrier
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    1. scibot 09 Oct 2024
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    sciencedirect.com/science/article/pii/S2666379124004841
  12. Sep 2024
  13. www.biorxiv.org www.biorxiv.org
    Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents
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  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacterial pore-forming toxin pneumolysin drives pathogenicity through host extracellular vesicles released during infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11357855/
  15. Aug 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke
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    sciencedirect.com/science/article/pii/S0223523424006767
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    ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes
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    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009768
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    The SGLT2 inhibitor dapagliflozin ameliorates renal fibrosis in hyperuricemic nephropathy
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    sciencedirect.com/science/article/pii/S2666379124004117
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    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
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    Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease
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    sciencedirect.com/science/article/pii/S2211124724009185
  21. Jul 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis
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    Tumor suppressor KEAP1 promotes HSPA9 degradation, controlling mitochondrial biogenesis in breast cancer
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  25. Jun 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in Prader-Willi syndrome gene necdin leads to attenuated cardiac contractility
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    ncbi.nlm.nih.gov/pmc/articles/PMC11144731/
  27. May 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multikinase inhibitors modulate non-constitutive proteasome expression in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11106389/
  29. 52.53.155.43 52.53.155.43
    Gingival-derived mesenchymal stem cells alleviate allergic asthma inflammation via HGF in animal models
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    52.53.155.43/77b0b81fcd376689bbdc4cf0ee4300be323e1a77/PIIS258900422401040X-html.html
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    Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor
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    sciencedirect.com/science/article/pii/S1934590924001383
  31. 52.53.155.43 52.53.155.43
    Disruption in<i>CYLC1</i>leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice
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    52.53.155.43/db83a72e264c6715c8b712c9f10e49747778439c/2024.01.11.24301040v1.full-html.html
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatokine ITIH3 Protects Against Hepatic Steatosis by Downregulating Mitochondrial Bioenergetics and De Novo Lipogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11059128/
  33. Apr 2024
  34. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025009/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbiota-derived cholic acid mediates neonatal brain immaturity and white matter injury under chronic hypoxia
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
  38. www.sciencedirect.com www.sciencedirect.com
    The nociceptive activity of peripheral sensory neurons is modulated by the neuronal membrane proteasome
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    sciencedirect.com/science/article/pii/S2211124724003863
  39. 52.53.155.43 52.53.155.43
    Haemolysins are essential to the pathogenicity of deep-sea Vibrio fluvialis
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
  41. www.sciencedirect.com www.sciencedirect.com
    TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction
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    sciencedirect.com/science/article/pii/S2211124724003425
  42. dx.doi.org dx.doi.org
    Genetic analysis, phenotype spectrum and functional study of rare osteogenesis imperfecta caused by CRTAP Variants
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      DOI: 10.1210/clinem/dgae025

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    dx.doi.org/10.1210/clinem/dgae025
  43. Mar 2024
  44. www.sciencedirect.com www.sciencedirect.com
    An early cell shape transition drives evolutionary expansion of the human forebrain
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      DOI: 10.1016/j.cell.2021.02.050

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    sciencedirect.com/science/article/pii/S0092867421002397
  45. www.sciencedirect.com www.sciencedirect.com
    Generation of two human induced pluripotent stem cell lines with BAX and BAK1 double knock-out using CRISPR/Cas9
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    sciencedirect.com/science/article/pii/S1873506124000758
  46. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
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    cell.com/iscience/abstract/S2589-0042(24)00367-5
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    Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes
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    sciencedirect.com/science/article/pii/S2211124724001876
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    Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
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      DOI: 10.1016/j.molcel.2024.01.028

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    sciencedirect.com/science/article/pii/S1097276524000959
  49. Feb 2024
  50. www.sciencedirect.com www.sciencedirect.com
    Pathogenic mycobacterium upregulates cholesterol 25-hydroxylase to promote granuloma development via foam cell formation
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    CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells
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    Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke
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    Rebalancing TGF-β/PGE2 breaks RT-induced immunosuppressive barriers by enhancing tumor-infiltrated dendritic cell homing
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    AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression
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    NSC48160 targets AMPKα to ameliorate nonalcoholic steatohepatitis by inhibiting lipogenesis and mitochondrial oxidative stress
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    Impact of Mutations Defining SARS-CoV-2 Omicron Subvariants BA.2.12.1 and BA.4/5 on Spike Function and Neutralization
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    Propionic Acid Driven by the Lactobacillus johnsonii Culture Supernatant Alleviates Colitis by Inhibiting M1 Macrophage Polarization by Modulating the MAPK Pathway in Mice
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    Detection of early prognostic biomarkers for metastasis of Ewing's sarcoma in pediatric patients
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    MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer
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  67. Oct 2023
  68. www.embopress.org www.embopress.org
    Cold-inducible lncRNA266 promotes browning and the thermogenic program in white adipose tissue
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    Cervicovaginal microbiota disorder combined with the change of cytosine phosphate guanine motif- toll like receptor 9 axis was associated with cervical cancerization
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    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
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  76. Sep 2023
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  90. May 2023
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    Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity
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    The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages
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    Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes
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    Nrf2 is expressed more extensively in neurons than in astrocytes following an acute epileptic seizure in rats
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  97. Apr 2023
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    Pyroptotic gasdermin exists in Mollusca and is vital to eliminating bacterial infection
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  122. Jul 2022
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    Mechanism of miR-132-3p Promoting Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson’s Disease
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    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
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  146. Dec 2021
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    Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
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    MiR-674-5p Suppresses the Proliferation and Migration of Glioma Cells by Targeting Cul4b
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    11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice
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  173. Jul 2021
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  201. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15277

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  202. www.sciencedirect.com www.sciencedirect.com
    Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment
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      DOI: 10.1016/j.celrep.2021.108802

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    sciencedirect.com/science/article/pii/S2211124721001169
  203. Feb 2021
  204. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Inhibition of human microsomal PGE2 synthase‐1 reduces seizure‐induced increases of P‐glycoprotein expression and activity at the blood‐brain barrier
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      RRID:AB_306371

      DOI: 10.1096/fj.201901460RR

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  205. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Amelioration of elastase‐induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice
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      DOI: 10.1111/bph.15057

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15057
  206. www.frontiersin.org www.frontiersin.org
    Long Noncoding RNA GAS5 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Regulating GDF5 and p38/JNK Signaling Pathway
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      DOI: 10.3389/fphar.2020.00701

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    frontiersin.org/articles/10.3389/fphar.2020.00701/full
  207. link.springer.com link.springer.com
    Changes in mitochondrial morphology modulate LPS-induced loss of calcium homeostasis in BV-2 microglial cells
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      anti-β-actin

      DOI: 10.1007/s10863-021-09878-4

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  208. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Comparative profiling of the synaptic proteome from Alzheimer’s disease patients with focus on the APOE genotype
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      DOI: 10.1186/s40478-019-0847-7

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  209. www.fasebj.org www.fasebj.org
    Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier
    1
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      RRID:AB_306371

      DOI: 10.1096/fj.201901460RR

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  210. Jan 2021
  211. link.springer.com link.springer.com
    Characterization of Glycosaminoglycan Disaccharide Composition in Astrocyte Primary Cultures and the Cortex of Neonatal Rats
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      DOI: 10.1007/s11064-020-03195-9

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  212. Dec 2020
  213. www.sciencedirect.com www.sciencedirect.com
    IFI16 knockdown in primary HIV-1 target cells
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      DOI: 10.1016/j.xpro.2020.100236

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  214. Nov 2020
  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Sortilin and Matrix Vesicles in Nε-Carboxymethyl-Lysine-Induced Diabetic Atherosclerotic Calcification
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      DOI: 10.2147/DMSO.S273029

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  216. Oct 2020
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
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      DOI: 10.1038/s41467-020-18761-6

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  218. Sep 2020
  219. www.sciencedirect.com www.sciencedirect.com
    Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion
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      DOI: 10.1016/j.celrep.2020.01.069

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  220. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
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      DOI: 10.1016/j.cmet.2020.04.011

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  221. elifesciences.org elifesciences.org
    The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations
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      DOI: 10.7554/eLife.16011

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  222. www.sciencedirect.com www.sciencedirect.com
    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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      DOI: 10.1016/j.cmet.2020.03.007

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  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline
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    1. scibot 17 Sep 2020
      RRID:AB_306371

      DOI: 10.7554/eLife.52946

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  224. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of ROCK signaling pathway accelerates enteric neural crest cell‐based therapy after transplantation in a rat hypoganglionic model
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      DOI: 10.1111/nmo.13895

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    onlinelibrary.wiley.com/doi/10.1111/nmo.13895
  225. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Necrostatin‐1 prevents the proapoptotic protein Bcl‐2/adenovirus E1B 19‐kDa interacting protein 3 from integration into mitochondria
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      DOI: 10.1111/jnc.14993

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14993
  226. www.sciencedirect.com www.sciencedirect.com
    An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication
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      DOI: 10.1016/j.celrep.2020.02.046

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  227. link.springer.com link.springer.com
    Hypercapnia Exacerbates the Blood–Brain Barrier Disruption Via Promoting HIF-1a Nuclear Translocation in the Astrocytes of the Hippocampus: Implication in Further Cognitive Impairment in Hypoxemic Adult Rats
    1
    1. scibot 14 Sep 2020
      RRID:AB_306371

      DOI: 10.1007/s11064-020-03038-7

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  228. www.mdpi.com www.mdpi.com
    Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Effect Complement-Mediated Neurotoxicity
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      RRID:AB_306371

      DOI: 10.3390/cells9071618

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    mdpi.com/2073-4409/9/7/1618
  229. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
    1
    1. scibot 13 Sep 2020
      β-actin

      DOI: 10.1158/2159-8290.CD-19-1228

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    cancerdiscovery.aacrjournals.org/content/10/9/1352
  230. www.sciencedirect.com www.sciencedirect.com
    Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis
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      DOI: 10.1016/j.cmet.2020.04.006

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  231. www.sciencedirect.com www.sciencedirect.com
    DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis
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      DOI: 10.1016/j.molcel.2020.02.022

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    sciencedirect.com/science/article/pii/S1097276520301155
  232. www.sciencedirect.com www.sciencedirect.com
    Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke
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      RRID:AB_306371

      DOI: 10.1016/j.brainres.2020.146879

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    sciencedirect.com/science/article/pii/S0006899320302353
  233. www.cell.com www.cell.com
    Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1
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    1. scibot 10 Sep 2020
      RRID:AB_306371

      DOI: 10.1016/j.celrep.2020.107999

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    cell.com/cell-reports/fulltext/S2211-1247(20)30984-0
  234. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle
    1
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      RRID:AB_306371

      DOI: 10.7554/eLife.52570

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    ncbi.nlm.nih.gov/pmc/articles/PMC7065909/
  235. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Down‐regulation of microRNA‐34c‐5p alleviates neuropathic pain via the SIRT1/STAT3 signaling pathway in rat models of chronic constriction injury of sciatic nerve
    1
    1. scibot 04 Sep 2020
      β‐actin

      DOI: 10.1111/jnc.14998

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  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres
    1
    1. scibot 04 Sep 2020
      ab8226

      DOI: 10.7554/eLife.49817

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    ncbi.nlm.nih.gov/pmc/articles/PMC6986873/
  237. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
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      AB_306371

      DOI: 10.1016/j.cmet.2020.06.004

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    sciencedirect.com/science/article/pii/S1550413120303053
  238. Jan 2020
  239. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
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    1. scibot 13 Jan 2020
      AB_306371

      DOI: 10.1016/j.celrep.2019.05.095

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    sciencedirect.com/science/article/pii/S221112471930734X
  240. www.sciencedirect.com www.sciencedirect.com
    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
    1
    1. scibot 13 Jan 2020
      RRID:AB_306371

      DOI: 10.1016/j.chom.2019.05.002

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    sciencedirect.com/science/article/pii/S1931312819302471
  241. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Specific Inhibition of SOD1 Selectively Promotes Apoptosis of Cancer Cells via Regulation of the ROS Signaling Network
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      RRID:AB_306371

      DOI: 10.1155/2019/9706792

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    ncbi.nlm.nih.gov/pmc/articles/PMC6398008/
  242. www.sciencedirect.com www.sciencedirect.com
    IMM-H004 reduced okadaic acid-induced neurotoxicity by inhibiting Tau pathology in vitro and in vivo
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      DOI: 10.1016/j.neuro.2019.09.012

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