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Self-amplifying RNA enables rapid, durable, integration-free programming of hiPSCs

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  DOI: 10.1016/j.crmeth.2026.101602
  
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sciencedirect.com/science/article/pii/S2667237526003036
Jul 2026
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PRDM16 modulates aspects of cell cycle dynamics and maturation in human iPSC-derived cardiomyocytes

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1. scibot 11 Jul 2026
  
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  DOI: 10.1016/j.stemcr.2026.103005
  
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sciencedirect.com/science/article/pii/S221367112600216X
May 2026
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Human PSC-derived sinoatrial node-cardiac plexus assembloids model innervation-associated maturation of pacemaker systems

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1. scibot 16 May 2026
  
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  DOI: 10.1016/j.stem.2026.04.018
  
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sciencedirect.com/science/article/pii/S193459092600158X
Apr 2026
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Engineered CAR-monocytes coordinate fibrosis clearance and cardiac regeneration following myocardial infarction

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1. scibot 25 Apr 2026
  
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  DOI: 10.1016/j.stem.2026.04.003
  
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sciencedirect.com/science/article/pii/S1934590926001438
Nov 2025
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Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages

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1. scibot 08 Nov 2025
  
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  DOI: 10.1016/j.stem.2025.10.008
  
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sciencedirect.com/science/article/pii/S1934590925003765
Oct 2025
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Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.stem.2025.09.011
  
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sciencedirect.com/science/article/pii/S1934590925003674
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Loss-of-function variants in ciliary genes confer high risk for tetralogy of Fallot

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1. scibot 23 Oct 2025
  
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  DOI: 10.1126/sciadv.adt0836
  
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  DOI: 10.1126/sciadv.adt0836
  
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science.org/doi/10.1126/sciadv.adt0836
Aug 2025
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Zbtb16 determines the fate plasticity of cardiovascular progenitors through IGF2BP3-mediated mRNA stabilization

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116127
  
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sciencedirect.com/science/article/pii/S2211124725008988
Jul 2025
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TRIM13 prevents cardiomyocyte injury by affecting apoptosis through interacting with CD3D in Myocardial Infarction

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1. scibot 30 Jul 2025
  
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sciencedirect.com/science/article/pii/S2589004225013628
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Distinct Protein Kinase C isoforms drive the cell cycle re-entry of two separate populations of neonatal rat ventricular cardiomyocytes

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1. scibot 22 Jul 2025
  
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  DOI: 10.1152/ajpcell.00506.2022
  
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2. scibot 16 Jul 2025
  
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  DOI: 10.1152/ajpcell.00506.2022
  
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52.53.155.43/5e829638e13346502617c4ce4a0d0647861e6e49/kebbe-et-al-2023-distinct-protein-kinase-c-isoforms-drive-the-cell-cycle-re-entry-of-two-separate-populations-of-html.html
Jun 2025
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Generation and differentiation of an induced pluripotent stem cell line (FMCPGHi006-A) from a patient with Duchenne muscular dystrophy carrying exons 42–43 deletion in the DMD gene

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1. scibot 25 Jun 2025
  
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  DOI: 10.1016/j.scr.2025.103756
  
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sciencedirect.com/science/article/pii/S1873506125001060
May 2025
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AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.99670
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12080999/
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A retinoic acid:YAP1 signaling axis controls atrial lineage commitment

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115687
  
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sciencedirect.com/science/article/pii/S2211124725004589
Sep 2024
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A broadly applicable method for quantifying cardiomyocyte cell division identifies proliferative events following myocardial infarction

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.crmeth.2024.100860
  
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sciencedirect.com/science/article/pii/S2667237524002388
Aug 2024
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Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity

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1. scibot 02 Aug 2024
  
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  DOI: 10.1186/s12967-023-04542-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10577912/
Jun 2024
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CircSMAD3 represses SMAD3 phosphorylation and ameliorates cardiac remodeling by recruiting YBX1

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110200
  
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sciencedirect.com/science/article/pii/S2589004224014251
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Single-nucleus Transcriptomics Reveals Cardiac Cell Type-specific Diversification in Metabolic Disease Transgenic Pigs

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1. scibot 14 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11166884/
Mar 2024
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MiR-431 promotes cardiomyocyte proliferation by targeting FBXO32 expression

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1. scibot 01 Mar 2024
  
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  DOI: 10.1002/jgm.3656
  
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onlinelibrary.wiley.com/doi/10.1002/jgm.3656
Feb 2024
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An Orexin Receptor 2 mediated heart-brain axis in cardiac pain

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1. scibot 18 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109067
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10867640/
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Genome engineering of a neuronal specific, optogenetic, induced pluripotent stem cell line

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  DOI: 10.1016/j.scr.2024.103317
  
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sciencedirect.com/science/article/pii/S1873506124000151
Oct 2023
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Long non-coding RNA LHX1-DT regulates cardiomyocyte differentiation through H2A.Z-mediated LHX1 transcriptional activation

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1. scibot 13 Oct 2023
  
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52.53.155.43/5a03f7b4c3af56aff3252303dae5ffb73d2bea0a/PIIS2589004223021284-html.html
Aug 2023
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Patient-specific iPSC-derived cardiomyocytes reveal variable phenotypic severity of Brugada syndrome

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.ebiom.2023.104741
  
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sciencedirect.com/science/article/pii/S2352396423003067
May 2023
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Engineering CpG island DNA methylation in pluripotent cells through synthetic CpG-free ssDNA insertion

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.crmeth.2023.100465
  
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sciencedirect.com/science/article/pii/S266723752300084X
Apr 2023
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Rapamycin treatment unmasks a sex-specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel

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1. scibot 08 Apr 2023
  
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  DOI: 10.1002/iub.2722
  
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iubmb.onlinelibrary.wiley.com/doi/10.1002/iub.2722
Mar 2023
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Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues

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  DOI: 10.1016/j.isci.2023.106302
  
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sciencedirect.com/science/article/pii/S2589004223003796
Jan 2023
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Multi-omics profiling visualizes dynamics of cardiac development and functions

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111891
  
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sciencedirect.com/science/article/pii/S2211124722017909
Oct 2022
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In vitro modeling of myocardial ischemia/reperfusion injury with murine or human 3D cardiac spheroids

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1. scibot 08 Oct 2022
  
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  DOI: 10.1016/j.xpro.2022.101751
  
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sciencedirect.com/science/article/pii/S2666166722006311
Sep 2022
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A scalable and tunable thermoreversible polymer for 3D human pluripotent stem cell biomanufacturing

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1. scibot 22 Sep 2022
  
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  DOI: 10.1016/j.isci.2022.104971
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9485071/
Jul 2022
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Direct reprogramming of adult adipose-derived regenerative cells toward cardiomyocytes using six transcriptional factors

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1. scibot 08 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104651
  
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sciencedirect.com/science/article/pii/S2589004222009233
Jun 2022
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Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

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  DOI: 10.1016/j.isci.2022.104582
  
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sciencedirect.com/science/article/pii/S2589004222008549
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Generation of the induced pluripotent stem cell line UNIBSi017-A from an individual with cardiospondylocarpofacial syndrome and the MAP3K7 c.737-7A>G variant

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1. scibot 09 Jun 2022
  
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sciencedirect.com/science/article/pii/S1873506122001866
Apr 2022
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RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development

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1. scibot 28 Apr 2022
  
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  DOI: 10.1016/j.devcel.2022.03.017
  
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sciencedirect.com/science/article/pii/S1534580722002118
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A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration

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1. scibot 08 Apr 2022
  
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  DOI: 10.1016/j.stem.2022.03.009
  
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sciencedirect.com/science/article/pii/S1934590922001072
Feb 2022
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Transcription factor protein interactomes reveal genetic determinants in heart disease

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  DOI: 10.1016/j.cell.2022.01.021
  
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pubmed.ncbi.nlm.nih.gov/35182466/
Jan 2022
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Generation of human induced pluripotent stem cell lines from three patients affected by Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) carrying heterozygous mutations in RYR2 gene

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1. scibot 28 Jan 2022
  
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  DOI: 10.1016/j.scr.2022.102688
  
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sciencedirect.com/science/article/pii/S187350612200037X
Aug 2021
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Induced pluripotent stem cell (iPSC) lines from two individuals carrying a homozygous (BGUi007-A) and a heterozygous (BGUi006-A) mutation in ELP1 for in vitro modeling of familial dysautonomia

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1. scibot 16 Aug 2021
  
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  DOI: 10.1016/j.scr.2021.102495
  
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sciencedirect.com/science/article/pii/S1873506121003421
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.001
  
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sciencedirect.com/science/article/pii/S2211124718317303
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Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy

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1. scibot 07 Aug 2021
  
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  DOI: 10.1016/j.scr.2021.102489
  
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sciencedirect.com/science/article/pii/S1873506121003366
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A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis

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  DOI: 10.1016/j.stem.2018.04.013
  
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sciencedirect.com/science/article/pii/S1934590918301759
Jun 2021
elifesciences.org elifesciences.org

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients

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1. scibot 11 Jun 2021
  
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  DOI: 10.7554/eLife.67481
  
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elifesciences.org/articles/67481
May 2021
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Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.12.016
  
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sciencedirect.com/science/article/pii/S1934590920306007
Apr 2021
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Human induced pluripotent stem cell (hiPSC) line UOMi006-A derived from PBMCs of a patient with Kearns-Sayre syndrome

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1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.scr.2021.102355
  
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sciencedirect.com/science/article/pii/S1873506121002014
Mar 2021
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Generation of human induced pluripotent stem cell (hiPSC) line UOMi005-A from PBMCs of a patient with Kearns-Sayre syndrome

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1. scibot 17 Mar 2021
  
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  DOI: 10.1016/j.scr.2021.102283
  
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sciencedirect.com/science/article/pii/S187350612100129X
Dec 2020
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Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency

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  DOI: 10.1016/j.stem.2020.11.005
  
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sciencedirect.com/science/article/pii/S1934590920305439
Oct 2020
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Generation of genomic-integration-free human induced pluripotent stem cells and the derived cardiomyocytes of X-linked dilated cardiomyopathy from DMD gene mutation

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1. scibot 20 Oct 2020
  
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sciencedirect.com/science/article/pii/S187350612030341X
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not

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  DOI: 10.26508/lsa.201900593
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7103425/
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Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation

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  DOI: 10.18632/aging.102587
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6949046/
www.cell.com www.cell.com

Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys

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  DOI: 10.1016/j.celrep.2018.11.001
  
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cell.com/cell-reports/abstract/S2211-1247(18)31730-3
academic.oup.com academic.oup.com

The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice

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1. scibot 08 Sep 2020
  
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  DOI: 10.1210/endocr/bqaa029
  
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academic.oup.com/endo/article/161/4/bqaa029/5760840
Jan 2020
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Generation of human induced pluripotent stem cell line carrying SCN5A C2204>T Brugada mutation (MUSli009-A-1) introduced by CRISPR/Cas9-mediated genome editing

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.scr.2019.101618
  
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sciencedirect.com/science/article/pii/S187350611930248X
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The lncRNA Locus Handsdown Regulates Cardiac Gene Programs and Is Essential for Early Mouse Development

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  DOI: 10.1016/j.devcel.2019.07.013
  
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sciencedirect.com/science/article/pii/S1534580719305854
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Distinct Molecular Trajectories Converge to Induce Naive Pluripotency

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  DOI: 10.1016/j.stem.2019.07.009
  
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sciencedirect.com/science/article/pii/S1934590919303078
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Untitled document

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  DOI: 10.1016/j.celrep.2019.01.079
  
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sciencedirect.com/science/article/pii/S2211124719301081
Nov 2018
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

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onlinelibrary.wiley.com/doi/full/10.1002/jcp.26758