254 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
  5. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224027652-main-html.html
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    Two-ended recombination at a Flp-nickase-broken replication fork
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    sciencedirect.com/science/article/pii/S1097276524009110
  7. Nov 2024
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    Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome
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    Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies
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    onlinelibrary.wiley.com/doi/full/10.1002/advs.202404109
  10. Sep 2024
  11. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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  12. Aug 2024
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    sciencedirect.com/science/article/pii/S1097276524006610
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    FACT mediates the depletion of macroH2A1.2 to expedite gene transcription
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    Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and epigenetic inheritance
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    Plasticity of the mitotic spindle in response to karyotype variation
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    cell.com/current-biology/fulltext/S0960-9822(24)00842-X
  17. Jul 2024
  18. www.biorxiv.org www.biorxiv.org
    MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks
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    The germline coordinates mitokine signaling
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    sciencedirect.com/science/article/pii/S0092867424006500
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    Dimerization of hub protein DYNLL1 and bZIP transcription factor CREB3L1 enhances transcriptional activation of CREB3L1 target genes like arginine vasopressin
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    sciencedirect.com/science/article/pii/S0196978124001220
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    Astrocytes modulate brain phosphate homeostasis via polarized distribution of phosphate uptake transporter PiT2 and exporter XPR1
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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Activity of Orthosteric Agonists and Allosteric Modulators at Metabotropic Glutamate Receptor 7
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    ncbi.nlm.nih.gov/pmc/articles/PMC10289241/
  23. Jun 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in Prader-Willi syndrome gene necdin leads to attenuated cardiac contractility
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  25. May 2024
  26. academic.oup.com academic.oup.com
    Glycerol Phenylbutyrate treatment of two patients with Monocarboxylate Transporter 8 deficiency
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      DOI: 10.1210/clinem/dgae146

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    academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgae146/7625621
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    Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
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    Genome-scale chromatin binding dynamics of RNA Polymerase II general transcription machinery components
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      DOI: 10.1038/s44318-024-00089-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11066129/
  29. Apr 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Unraveling the landscapes and regulation of scanning, leaky scanning, and 48S initiation complex conformations
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    sciencedirect.com/science/article/pii/S2211124724004546
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    An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993188/
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    14-3-3 binding motif phosphorylation disrupts Hdac4-organized condensates to stimulate cardiac reprogramming
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    sciencedirect.com/science/article/pii/S2211124724003826
  34. Mar 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C17orf80 binds the mitochondrial genome to promote its replication
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  36. Feb 2024
  37. www.cell.com www.cell.com
    Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma
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    cell.com/cell-metabolism/abstract/S1550-4131(24)00018-4
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    Histone methylation readers MRG1/2 interact with PIF4 to promote thermomorphogenesis in Arabidopsis
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    sciencedirect.com/science/article/pii/S2211124724000548
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    Asymmetric neurons are necessary for olfactory learning in the Drosophila brain
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  40. Jan 2024
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    ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1
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    Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice
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  43. link.springer.com link.springer.com
    Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
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      DOI: 10.1038/s41467-024-44687-4

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  44. Dec 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    Prothymosin α accelerates dengue virus-induced thrombocytopenia
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    In vivo identification of astrocyte and neuron subproteomes by proximity-dependent biotinylation
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  48. Nov 2023
  49. 52.53.155.43 52.53.155.43
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      DOI: 10.3389/fncel.2020.552213

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  50. Oct 2023
  51. www.sciencedirect.com www.sciencedirect.com
    N6-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation
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    sciencedirect.com/science/article/abs/pii/S1097276523007475
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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      DOI: 10.1016/j.isci.2023.107887

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    ncbi.nlm.nih.gov/pmc/articles/PMC10522999/
  53. Sep 2023
  54. www.sciencedirect.com www.sciencedirect.com
    RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
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      DOI: 10.1016/j.molcel.2023.08.029

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    sciencedirect.com/science/article/pii/S1097276523006937
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    TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes
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      DOI: 10.1016/j.celrep.2023.113177

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    sciencedirect.com/science/article/pii/S2211124723011890
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    High temperature inhibits vascular development via the PIF4-miR166-HB15 module in Arabidopsis
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      DOI: 10.1016/j.cub.2023.06.049

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    Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells
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    Molecular basis of interactions between CaMKII and α-actinin-2 that underlie dendritic spine enlargement
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  59. Aug 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale chromatin interaction dynamic measurements for key components of the RNA Pol II general transcription machinery
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  61. 52.53.155.43 52.53.155.43
    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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    Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
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    FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth
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    Regulation of feeding and energy homeostasis by clock-mediated Gart in Drosophila
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  66. Jul 2023
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    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
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    Transcription factors interact with RNA to regulate genes
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    Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies
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  70. Jun 2023
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    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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  72. dx.doi.org dx.doi.org
    Novel MKRN3 Missense Mutations Associated with Central Precocious Puberty Reveal Distinct Effects on Ubiquitination
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  73. May 2023
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    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
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    Co-transcriptional genome surveillance by HUSH is coupled to termination machinery
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  77. Apr 2023
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    Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
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  79. academic.oup.com academic.oup.com
    Germline and somatic inactivating FLCN variants in parathyroid cancer and atypical parathyroid tumors
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    APP and Bace1: differential effect of cholesterol enrichment on processing and plasma membrane mobility
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    ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer
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  82. Mar 2023
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    Simultaneous activation of Tor and suppression of ribosome biogenesis by TRIM-NHL proteins promotes terminal differentiation
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    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
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  85. Jan 2023
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    CRISPR-free, programmable RNA pseudouridylation to suppress premature termination codons
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    mRNA transport, translation, and decay in adult mammalian central nervous system axons
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  88. Dec 2022
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    Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression
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    An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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  93. Nov 2022
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    PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation
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    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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  96. Oct 2022
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    BCAT1 redox function maintains mitotic fidelity
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    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
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  99. www.nature.com www.nature.com
    Regulation of KDM5C stability and enhancer reprogramming in breast cancer
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  100. Sep 2022
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    Lateral axonal modulation is required for stimulus-specific olfactory conditioning in Drosophila
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  102. Aug 2022
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
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    A modified CUT&RUN-seq technique for qPCR analysis of chromatin-protein interactions
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  106. Jul 2022
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    Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction
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  108. Jun 2022
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    Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals
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    Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila
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    Tandem immuno-purification of affinity-tagged proteins from mouse testis extracts for MS analysis
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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
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  113. May 2022
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    TIR domains of plant immune receptors are 2′,3′-cAMP/cGMP synthetases mediating cell death
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    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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    Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation
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  117. Apr 2022
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    Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation
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  119. Mar 2022
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
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    The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes
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    ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
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  124. Feb 2022
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    Transcription factor protein interactomes reveal genetic determinants in heart disease
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    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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    Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing
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    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
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  129. Jan 2022
  130. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development
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    Control of mammalian locomotion by ventral spinocerebellar tract neurons
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    The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
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    WASH interacts with Ku to regulate DNA double-stranded break repair
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    Subcellular and regional localization of mRNA translation in midbrain dopamine neurons
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  135. Dec 2021
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    Neuropeptide F inhibits dopamine neuron interference of long-term memory consolidation in Drosophila
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  137. Nov 2021
  138. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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    A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
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    Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks
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    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
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  143. www.sciencedirect.com www.sciencedirect.com
    Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
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  144. Oct 2021
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    The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly
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    Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway
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    NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain
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    Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription
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    CWI pathway participated in vegetative growth and pathogenicity through a downstream effector AflRlm1 in Aspergillus flavus
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  150. www.jneurosci.org www.jneurosci.org
    Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1
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  151. Sep 2021
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    Generation and characterization of an endogenously tagged SPG11- human iPSC line by CRISPR/Cas9 mediated knock-in
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    Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription
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  155. Aug 2021
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    Structured elements drive extensive circular RNA translation
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    The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms
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  204. Jan 2021
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    Ecd promotes U5 snRNP maturation and Prp8 stability
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    GSK-3β Disrupts Neuronal Oscillatory Function to Inhibit Learning and Memory in Male Rats
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  207. Dec 2020
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    Antagonistic Regulation by CPN60A and CLPC1 of TRXL1 that Regulates MDH Activity Leading to Plant Disease Resistance and Thermotolerance
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    Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics
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  210. Nov 2020
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    A Ca2+-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration
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  212. Oct 2020
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    Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling
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    Olfactory Stimulation Regulates the Birth of Neurons That Express Specific Odorant Receptors
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  215. Sep 2020
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    MYC Controls the Epstein-Barr Virus Lytic Switch
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    The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
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    ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
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    p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells
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    Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
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    The Protein Translocation Defect of MCT8L291R Is Rescued by Sodium Phenylbutyrate
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    Promiscuous Binding of Microprotein Mozart1 to γ-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation
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    Translatome Analyses Using Conditional Ribosomal Tagging in GABAergic Interneurons and Other Sparse Cell Types
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    The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1
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    Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation
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    KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
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    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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    MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells
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    Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis
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    G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
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    PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation
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    Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus
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    Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4
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  234. Jan 2020
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    SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation
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    Structural Basis of an Asymmetric Condensin ATPase Cycle
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    A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer
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    Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader
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      DOI: 10.1016/j.chembiol.2019.11.006

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    TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma
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    SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States
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    Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons
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      DOI: 10.7554/eLife.44423

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