Hypothesis

43 Matching Annotations

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Oral GLP-1 receptor agonist promotes astrocyte-neuron lactate and lipid transfer with neuroprotective effects

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.cmet.2026.05.014
  
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sciencedirect.com/science/article/pii/S155041312600224X
Jun 2026
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Lactate-driven H3K18 lactylation promotes cisplatin resistance in bladder cancer via HNRNPF-Parkin mediated mitophagy

1
1. scibot 16 Jun 2026
  
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  DOI: 10.1016/j.drup.2026.101435
  
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sciencedirect.com/science/article/pii/S1368764626000865
May 2026
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AF9-KLF2 gene regulatory circuit links histone lactylation to metabolic reprogramming and breast cancer progression

1
1. scibot 28 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117429
  
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sciencedirect.com/science/article/pii/S2211124726005073
Apr 2026
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

m5C-Modified tRF3b-CysGCA-23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

1
1. scibot 02 Apr 2026
  
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  DOI: 10.1002/advs.202522294
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522294
Mar 2026
pubs.acs.org pubs.acs.org

Bisphenol A Promotes Ovarian Cancer Proliferation and Migration through the HK2/H3K18la/IGF2BP3 Sequential Regulatory Axis

1
1. scibot 31 Mar 2026
  
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  DOI: 10.1021/acs.jafc.5c16242
  
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pubs.acs.org/doi/10.1021/acs.jafc.5c16242
Aug 2025
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A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma

1
1. scibot 20 Aug 2025
  
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  RRID:AB_3076695
  
  DOI: 10.1016/j.xcrm.2025.102292
  
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sciencedirect.com/science/article/pii/S2666379125003659
May 2025
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Metabolic reprogramming through histone lactylation in microglia and macrophages recruits CD8+ T lymphocytes and aggravates spinal cord injury

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.neuron.2025.04.003
  
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sciencedirect.com/science/article/pii/S0896627325002594
Feb 2025
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Lactate shuttling links histone lactylation to adult hippocampal neurogenesis in mice

7
1. scibot 07 Feb 2025
  
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  RRID:AB_3076695
  
  DOI: 10.1016/j.devcel.2024.12.021
  
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2. scibot 06 Feb 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
3. scibot 05 Feb 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
4. scibot 04 Feb 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
5. scibot 03 Feb 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
6. scibot 02 Feb 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
7. scibot 01 Feb 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S1534580724007603
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Lactate shuttling links histone lactylation to adult hippocampal neurogenesis in mice

25
1. scibot 31 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
2. scibot 30 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
3. scibot 29 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
4. scibot 28 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
5. scibot 27 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
6. scibot 26 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
7. scibot 25 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
8. scibot 24 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
9. scibot 23 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
10. scibot 22 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
11. scibot 21 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
12. scibot 20 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
13. scibot 19 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
14. scibot 18 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
15. scibot 17 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
16. scibot 16 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
17. scibot 15 Jan 2025
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
18. scibot 14 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
19. scibot 13 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
20. scibot 12 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
21. scibot 11 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
22. scibot 10 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
23. scibot 09 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
24. scibot 08 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_3076695
25. scibot 07 Jan 2025
  
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  RRID:AB_3076695
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S1534580724007603
Nov 2024
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.cmet.2024.10.015
  
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sciencedirect.com/science/article/pii/S155041312400411X
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110188
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233973/
May 2024
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Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114180
  
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sciencedirect.com/science/article/pii/S2211124724005084
Apr 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Andrographolide regulates H3 histone lactylation by interfering with p300 to alleviate aortic valve calcification

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1. scibot 25 Apr 2024
  
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  DOI: 10.1111/bph.16332
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16332

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