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Aug 2026
www.sciencedirect.com www.sciencedirect.com

The Y105 phosphosite between the SH3.1 and SH3.2 domains of Nck1 regulates its binding to CD3ϵ

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sciencedirect.com/science/article/pii/S2589004226024971
Jul 2026
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ABL kinase inactivation induces transcription-replication conflicts and impairs replication fork progression in metastatic small cell lung cancer

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sciencedirect.com/science/article/pii/S2211124726007771
Mar 2026
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IgE-dependent anaphylaxis is regulated by sphingolipid binding to activating and inhibitory CD300 family members

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sciencedirect.com/science/article/pii/S2211124726001324
Mar 2025
www.biorxiv.org www.biorxiv.org

Identification of the Lipid Oxygen Radical Defense pathway and its epigenetic control

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  DOI: 10.1101/2025.02.25.640160
  
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biorxiv.org/content/10.1101/2025.02.25.640160v1
Jan 2025
52.53.155.43 52.53.155.43

bqaf003-html.html

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  DOI: 10.1210/endocr/bqaf003
  
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52.53.155.43/dd2db392eda7c66b1fa20a070d0eb1409720cb82/bqaf003-html.html
Sep 2024
www.jneurosci.org www.jneurosci.org

Untitled document

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  DOI: 10.1523/JNEUROSCI.0128-18.2018
  
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jneurosci.org/content/38/39/8345
Apr 2024
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Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice

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sciencedirect.com/science/article/pii/S2211124724004728
Mar 2024
rupress.org rupress.org

The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis

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1. scibot 21 Mar 2024
  
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  DOI: 10.1083/jcb.202307147
  
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rupress.org/jcb/article/223/3/e202307147/276492/The-Cby3-ciBAR1-complex-positions-the-annulus
Aug 2023
52.53.155.43 52.53.155.43

PIIS2589004223016838-html.html

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  DOI: 10.1016/j.isci.2023.107606
  
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52.53.155.43/0595295f970fa120203481e8752220bf0b62043f/PIIS2589004223016838-html.html
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ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo

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  DOI: 10.1016/j.isci.2023.107467
  
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sciencedirect.com/science/article/pii/S2589004223015444
Jul 2023
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GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells

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sciencedirect.com/science/article/pii/S2589004223014189
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Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery

1
1. scibot 15 Jul 2023
  
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sciencedirect.com/science/article/pii/S2211124723008185
May 2023
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CKB regulates BCAR1 phosphorylation to facilitate DNA damage repair

1
1. scibot 13 May 2023
  
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  DOI: 10.1016/j.isci.2023.106684
  
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sciencedirect.com/science/article/pii/S2589004223007617
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Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation

1
1. scibot 10 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112490
  
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sciencedirect.com/science/article/pii/S2211124723005016
Apr 2023
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Differential Hsp90-dependent gene expression is strain-specific and common among yeast strains

1
1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106635
  
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sciencedirect.com/science/article/pii/S2589004223007125
Jan 2023
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Evolutionarily conserved regulators of tau identify targets for new therapies

1
1. scibot 07 Jan 2023
  
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  DOI: 10.1016/j.neuron.2022.12.012
  
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sciencedirect.com/science/article/pii/S0896627322010856
Aug 2022
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ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain

1
1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111268
  
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sciencedirect.com/science/article/pii/S2211124722010865
Jul 2022
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A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand

1
1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111039
  
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sciencedirect.com/science/article/pii/S2211124722008336
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EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks

1
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  DOI: 10.1016/j.celrep.2022.111031
  
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sciencedirect.com/science/article/pii/S2211124722008257
May 2022
aacrjournals.org aacrjournals.org

Irreversible FLT3 Inhibitor FF-10101 Is Active Against a Diversity of FLT3 Inhibitor Resistance Mechanisms

1
1. scibot 14 May 2022
  
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  DOI: 10.1158/1535-7163.MCT-21-0317
  
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aacrjournals.org/mct/article/21/5/844/694774/The-Irreversible-FLT3-Inhibitor-FF-10101-Is-Active
Apr 2022
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Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis

1
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sciencedirect.com/science/article/pii/S2589004222004813
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility

1
1. scibot 04 Feb 2022
  
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  DOI: 10.1016/j.cell.2019.03.047
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8808721/
Jan 2022
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ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

1
1. scibot 29 Jan 2022
  
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  DOI: 10.1016/j.neuron.2021.12.035
  
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sciencedirect.com/science/article/pii/S0896627321010904
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Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses

1
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  DOI: 10.1016/j.molcel.2021.12.006
  
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sciencedirect.com/science/article/pii/S1097276521010686
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C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane

1
1. scibot 08 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110226
  
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sciencedirect.com/science/article/pii/S2211124721017307
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts

1
1. scibot 29 Nov 2021
  
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  DOI: 10.1016/j.neuron.2019.02.034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
academic.oup.com academic.oup.com

Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma

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1. scibot 25 Nov 2021
  
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  DOI: 10.1210/endocr/bqab214
  
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academic.oup.com/endo/article/163/1/bqab214/6396829
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NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load

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1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.72034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8547963/
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Secretory mouse quiescin sulfhydryl oxidase 1 aggregates defected human and mouse spermatozoa in vitro and in vivo

1
1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.isci.2021.103167
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8506963/
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Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling

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  DOI: 10.1016/j.jbc.2021.101291
  
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sciencedirect.com/science/article/pii/S0021925821010966
Aug 2021
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NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells

1
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sciencedirect.com/science/article/pii/S2211124721009463
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Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase

1
1. scibot 14 Aug 2021
  
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  DOI: 10.1523/JNEUROSCI.2519-16.2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6705738/
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USP8 deubiquitinates the leptin receptor and is necessary for leptin-mediated synapse formation

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1. scibot 14 Aug 2021
  
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  DOI: 10.1210/en.2019-00107
  
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academic.oup.com/endo/article/160/8/1982/5518337
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Untitled document

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  DOI: 10.1210/en.2017-00469
  
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academic.oup.com/endo/article/158/10/3235/4058081
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  DOI: 10.7554/eLife.37776
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6239434/
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Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate

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  DOI: 10.1016/j.cels.2017.08.001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6261251/
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KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin

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Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

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Sperm Behavior and Response to Melatonin under Capacitating Conditions in Three Sheep Breeds Subject to the Equatorial Photoperiod

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ncbi.nlm.nih.gov/pmc/articles/PMC8235450/
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Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth

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Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis

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Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM

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Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors

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Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

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Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer

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Underlying molecular mechanism in the modulation of the ram sperm acrosome reaction by progesterone and 17β-estradiol

1
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sciencedirect.com/science/article/pii/S0378432020304395
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Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis

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sciencedirect.com/science/article/pii/S2211124721001315
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The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

1
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Critical role of Syk-dependent STAT1 activation in innate antiviral immunity

1
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sciencedirect.com/science/article/pii/S2211124720316168
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3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice

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An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis

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cell.com/current-biology/abstract/S0960-9822(20)31495-0
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Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner

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jneurosci.org/content/40/43/8248
Oct 2020
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Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

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ncbi.nlm.nih.gov/pmc/articles/PMC7553310/
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The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex

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jneurosci.org/content/40/40/7625
Sep 2020
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Roles of Pyk2 in signal transduction after gonadotropin‐releasing hormone receptor stimulation

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onlinelibrary.wiley.com/doi/10.1002/jcp.30077
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Involvement of progesterone and estrogen receptors in the ram sperm acrosome reaction

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A Bartonella Effector Acts as Signaling Hub for Intrinsic STAT3 Activation to Trigger Anti-inflammatory Responses

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sciencedirect.com/science/article/pii/S1931312820300548
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TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL

1
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Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

1
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ncbi.nlm.nih.gov/pmc/articles/PMC6742478/
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

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Timely Inhibitory Circuit Formation Controlled by Abl1 Regulates Innate Olfactory Behaviors in Mouse

1
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A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis

1
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  DOI: 10.1016/j.celrep.2019.11.018
  
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Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

1
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  DOI: 10.1016/j.celrep.2019.05.017
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Extracellular vesicles from oviductal isthmus and ampulla stimulate the induced acrosome reaction and signaling events associated with capacitation in bovine spermatozoa

1
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  DOI: 10.1002/jcb.29522
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcb.29522
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Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn‐independent effect of tau on calcium

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  DOI: 10.1002/jnr.24517
  
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onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24517
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

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  DOI: 10.1016/j.cell.2019.09.008
  
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3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival

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  DOI: 10.1016/j.celrep.2019.10.054
  
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A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease

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  DOI: 10.1021/acschemneuro.9b00396
  
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  DOI: 10.1016/j.celrep.2019.01.018
  
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Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response

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Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination

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Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR

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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

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Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor

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The Plasticity of the Hsp90 Co-chaperone System

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A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.

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A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

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Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling

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A Tunable Brake for HECT Ubiquitin Ligases

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Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency

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Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis

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