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BCL-xL as a therapeutic target in cetuximab-refractory colorectal cancer

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1. scibot 10 Feb 2026
  
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  DOI: 10.1038/s41419-026-08434-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12876907/
Dec 2025
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1-s2.0-S2212877825002042-main-html.html

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  DOI: 10.1016/j.molmet.2025.102297
  
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54.241.53.176/da28179ce785728cc3e84d5d1ca4c5e2ba7fa6b4/1-s2.0-S2212877825002042-main-html.html
Sep 2025
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PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113408
  
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sciencedirect.com/science/article/pii/S2589004225016694
Apr 2025
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Targeted splicing approach for alleviation of a neurexin 1 haploinsufficiency model

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1. scibot 17 Apr 2025
  
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  DOI: 10.1038/s41380-025-03017-w
  
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link.springer.com/article/10.1038/s41380-025-03017-w
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A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions

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  DOI: 10.1016/j.celrep.2025.115467
  
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sciencedirect.com/science/article/pii/S2211124725002384
Mar 2025
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Translation dysregulation in cancer as a source for targetable antigens

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.03.003
  
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sciencedirect.com/science/article/pii/S1535610825000820
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Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein

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  DOI: 10.1016/j.cmet.2025.01.022
  
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sciencedirect.com/science/article/pii/S1550413125000221
Feb 2025
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Haploinsufficiency of GABAA receptor-associated Clptm1 enhances phasic and tonic inhibitory neurotransmission, suppresses excitatory synaptic plasticity, and impairs memory

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1. scibot 11 Feb 2025
  
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  DOI: 10.1523/JNEUROSCI.0521-24.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11308325/
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G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration

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1. scibot 04 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115237
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11923778/
Jan 2025
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Dynamic molecular architecture of the synaptonemal complex

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1. scibot 24 Jan 2025
  
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  DOI: 10.1126/sciadv.adq9374
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11753403/
Dec 2024
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Parameters for sensing lipid loosening at the inner nuclear membrane by amphipathic helices

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1. scibot 21 Dec 2024
  
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  DOI: 10.1101/2024.11.14.623600
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11601446/
Nov 2024
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PP2A licenses the FANCD2/FANCI complex for chromosome loading

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114971
  
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sciencedirect.com/science/article/pii/S2211124724013226
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PI3K/Akt inhibition promotes AR activity and prostate cancer cell proliferation through p35-CDK5 modulation

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.bbadis.2024.167568
  
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sciencedirect.com/science/article/pii/S0925443924005623
Oct 2024
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CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.celrep.2024.114797
  
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sciencedirect.com/science/article/pii/S2211124724011483
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage

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1. scibot 26 Sep 2024
  
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  DOI: 10.1091/mbc.E23-09-0382
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11244170/
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CTENO64 Is Required for Coordinated Paddling of Ciliary Comb Plate in Ctenophores

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1. scibot 25 Sep 2024
  
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  AB_477593
  
  DOI: 10.1016/j.cub.2019.08.059
  
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sciencedirect.com/science/article/pii/S0960982219311091
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Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular Arrest

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2019.07.102
  
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sciencedirect.com/science/article/pii/S2211124719310186
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The ATP-exporting channel Pannexin 1 promotes CD8+ T cell effector and memory responses

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1. scibot 26 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110290
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11263643/
52.53.155.43 52.53.155.43

Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110547
  
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52.53.155.43/ec8bf473a95e0f0a14821b5e61884b766010f004/1-s2.0-S2589004224017723-main-html.html
www.cell.com www.cell.com

Regulation of the DLC3 tumor suppressor by a novel phosphoswitch

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110203
  
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cell.com/iscience/abstract/S2589-0042(24)01428-7
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair

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  DOI: 10.1016/j.isci.2024.109524
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993188/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108958
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
Jan 2024
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Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells

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1. scibot 25 Jan 2024
  
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  DOI: 10.1016/j.devcel.2024.01.002
  
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sciencedirect.com/science/article/pii/S1534580724000029
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DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108760
  
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sciencedirect.com/science/article/pii/S2589004223028377
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Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair

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  DOI: 10.1016/j.celrep.2023.113656
  
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sciencedirect.com/science/article/pii/S2211124723016674
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A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope

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  DOI: 10.1083/jcb.202304026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10309186/
Oct 2023
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Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import

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1. scibot 17 Oct 2023
  
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  DOI: 10.1126/sciadv.adi5548
  
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science.org/doi/10.1126/sciadv.adi5548
Sep 2023
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Microtubule detyrosination by VASH1/SVBP is regulated by the conformational state of tubulin in the lattice

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1. scibot 19 Sep 2023
  
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  DOI: 10.1016/j.cub.2023.07.062
  
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sciencedirect.com/science/article/abs/pii/S0960982223010011
Aug 2023
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Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import

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1. scibot 26 Aug 2023
  
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  DOI: 10.1126/sciadv.adi5548
  
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science.org/doi/10.1126/sciadv.adi5548
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Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms

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  DOI: 10.1016/j.ebiom.2023.104752
  
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sciencedirect.com/science/article/pii/S2352396423003171
Jul 2023
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Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112802
  
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sciencedirect.com/science/article/pii/S2211124723008136
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Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors

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  DOI: 10.1016/j.celrep.2023.112714
  
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sciencedirect.com/science/article/pii/S2211124723007258
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Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway

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1. scibot 01 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112721
  
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sciencedirect.com/science/article/pii/S2211124723007325
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Recruitment of Polo-like kinase couples synapsis to meiotic progression via inactivation of CHK-2

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1. scibot 16 Mar 2023
  
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  RRID:AB_310035
  
  DOI: 10.7554/eLife.84492
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9998088/
Oct 2022
www.nature.com www.nature.com

The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma

1
1. scibot 28 Oct 2022
  
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  RRID:AB_310035
  
  DOI: 10.1038/s41467-022-33746-3
  
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nature.com/articles/s41467-022-33746-3
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Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia

1
1. scibot 23 Oct 2022
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.cub.2022.09.061
  
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sciencedirect.com/science/article/pii/S0960982222016037
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EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules

1
1. scibot 13 Aug 2022
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.cub.2022.07.027
  
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Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

1
1. scibot 27 Jul 2022
  
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  RRID:AB_310035
  
  DOI: 10.7554/eLife.75513
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9296133/
Apr 2022
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Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements

1
1. scibot 21 Apr 2022
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.devcel.2022.03.014
  
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sciencedirect.com/science/article/pii/S1534580722002088
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IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

1
1. scibot 22 Dec 2021
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.celrep.2021.110138
  
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Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation

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1. scibot 01 Dec 2021
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.devcel.2021.11.009
  
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Analysis of meiosis in Pristionchus pacificus reveals plasticity in homolog pairing and synapsis in the nematode lineage

1
1. scibot 25 Sep 2021
  
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  RRID:AB_310035
  
  DOI: 10.7554/eLife.70990
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8455136/
Aug 2021
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MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses

1
1. scibot 01 Aug 2021
  
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  RRID:AB_310035
  
  DOI: 10.1083/jcb.201810023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6504910/
May 2021
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Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control

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  RRID:AB_310035
  
  DOI: 10.1016/j.cub.2020.05.004
  
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sciencedirect.com/science/article/pii/S0960982220306436
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Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin

1
1. scibot 24 Feb 2021
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.cub.2020.11.055
  
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cell.com/current-biology/fulltext/S0960-9822(20)31768-1
Sep 2020
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WRNIP1 Is Recruited to DNA Interstrand Crosslinks and Promotes Repair

1
1. scibot 23 Sep 2020
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.celrep.2020.107850
  
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sciencedirect.com/science/article/pii/S2211124720308317
Jan 2020
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Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function

1
1. scibot 13 Jan 2020
  
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  RRID:AB_310035
  
  DOI: 10.1074/jbc.RA119.010027
  
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jbc.org/content/294/43/15743.full
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Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage

1
1. scibot 13 Jan 2020
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.celrep.2019.05.003
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Regulation of T‐type Ca2+ channel expression by interleukin‐6 in sensory‐like ND7/23 cells post‐herpes simplex virus (HSV‐1) infection

1
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  RRID:AB_310035
  
  DOI: 10.1111/jnc.14697
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14697
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Untitled document

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  DOI: 10.1016/j.celrep.2018.12.106
  
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Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

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1. scibot 13 Jan 2020
  
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  RRID:AB_310035
  
  DOI: 10.1016/j.neuron.2019.02.018
  
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sciencedirect.com/science/article/pii/S0896627319301539
Nov 2018
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Ouabain increases neuronal branching in hippocampus and improves spatial memory

1
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6070338/
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Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

1
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A compartmentalized signaling network mediates crossover control in meiosis

1
1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5906097/
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Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength

1
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sciencedirect.com/science/article/pii/S0896627317311868
Nov 2017
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Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

1
1. scibot 08 Nov 2017
  
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  anti-Tubulin (clone DM1A, mouse, Sigma; alternatively, clone YL1/2, rat, Millipore Bioscience Research Reagents)
  
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