227 Matching Annotations
  1. Oct 2024
  2. link.springer.com link.springer.com
    Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors
    1
    1. scibot 08 Oct 2024
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      DOI: 10.1038/s41596-024-01058-z

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    link.springer.com/article/10.1038/s41596-024-01058-z
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism
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    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.isci.2024.110702

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    ncbi.nlm.nih.gov/pmc/articles/PMC11388182/
  5. www.sciencedirect.com www.sciencedirect.com
    PICKLE-mediated nucleosome condensing drives H3K27me3 spreading for the inheritance of Polycomb memory during differentiation
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    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S1097276524006920
  6. Aug 2024
  7. academic.oup.com academic.oup.com
    Loss of RBBP4 results in defective inner cell mass, severe apoptosis, hyperacetylated histones and preimplantation lethality in mice
    1
    1. scibot 02 Aug 2024
      rabbit anti-H3K27me3

      DOI: 10.1093/biolre/ioaa046

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    academic.oup.com/biolreprod/article-abstract/103/1/13/5819637
  8. stemcellres.biomedcentral.com stemcellres.biomedcentral.com
    Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome
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    1. scibot 02 Aug 2024
      anti-mouse H3K27me3 rabbit polyclonal

      DOI: 10.1186/s13287-020-02051-5

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    stemcellres.biomedcentral.com/article/10.1186/s13287-020-02051-5
  9. Jul 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Implications of noncoding regulatory functions in the development of insulinomas
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    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S2666979X24001988
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    Cell-type-specific loops linked to RNA polymerase II elongation in human neural differentiation
    1
    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.xgen.2024.100606

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    sciencedirect.com/science/article/pii/S2666979X24002003
  12. Jun 2024
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114291

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    pmc.ncbi.nlm.nih.gov/articles/PMC11238474/
  14. May 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
    3
    1. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    2. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    3. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    sciencedirect.com/science/article/pii/S0092867424004732
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    Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
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    1. scibot 03 May 2024
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      DOI: 10.1016/j.cell.2024.04.005

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    sciencedirect.com/science/article/pii/S0092867424004008
  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency
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    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.015

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    sciencedirect.com/science/article/pii/S1097276524001345
  19. www.sciencedirect.com www.sciencedirect.com
    Alternative splicing decouples local from global PRC2 activity
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.011

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    sciencedirect.com/science/article/pii/S1097276524001308
  20. Feb 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination
    1
    1. scibot 02 Feb 2024
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      DOI: 10.7554/eLife.95337

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830130/
  22. Jan 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Optimizing rice grain size by attenuating phosphorylation-triggered functional impairment of a chromatin modifier ternary complex
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.013

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    sciencedirect.com/science/article/pii/S1534580723006937
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    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.007

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    sciencedirect.com/science/article/pii/S1097276523010262
  25. www.sciencedirect.com www.sciencedirect.com
    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.11.033

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    sciencedirect.com/science/article/pii/S0092867423013193
  26. Nov 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Lineage-specific 3D genome organization is assembled at multiple scales by IKAROS
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cell.2023.10.023

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    sciencedirect.com/science/article/pii/S0092867423011741
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.xgen.2023.100424

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    sciencedirect.com/science/article/pii/S2666979X23002501
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    Epigenetic and transcriptional regulation of CCL17 production by glucocorticoids in arthritis
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.isci.2023.108079

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    sciencedirect.com/science/article/pii/S2589004223021569
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    ZEB2 and MEIS1 independently contribute to hematopoiesis via early hematopoietic enhancer activation
    1
    1. scibot 01 Oct 2023
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      DOI: 10.1016/j.isci.2023.107893

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    sciencedirect.com/science/article/pii/S2589004223019703
  32. Aug 2023
  33. 52.53.155.43 52.53.155.43
    ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112937

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112937

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    52.53.155.43/5c44b570825d260ed49e3beddaa9d47779a57883/PIIS2211124723009488-html.html
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone variants shape chromatin states in Arabidopsis
    1
    1. scibot 03 Aug 2023
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      DOI: 10.7554/eLife.87714

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    ncbi.nlm.nih.gov/pmc/articles/PMC10393023/
  35. Jul 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112894

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    sciencedirect.com/science/article/pii/S2211124723009051
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    The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.devcel.2023.07.002

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    sciencedirect.com/science/article/abs/pii/S1534580723003325
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    Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease
    2
    1. scibot 22 Jul 2023
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      DOI: 10.1016/j.ebiom.2023.104720

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      DOI: 10.1016/j.ebiom.2023.104720

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    sciencedirect.com/science/article/pii/S2352396423002852
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    TONSOKU is required for the maintenance of repressive chromatin modifications in Arabidopsis
    1
    1. scibot 04 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112738

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    sciencedirect.com/science/article/pii/S2211124723007490
  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Early chromosome condensation by XIST builds A-repeat RNA density that facilitates gene silencing
    1
    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112686

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    sciencedirect.com/science/article/pii/S2211124723006976
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    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
    1
    1. scibot 27 Jun 2023
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      DOI: 10.1016/j.isci.2023.107115

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    sciencedirect.com/science/article/pii/S2589004223011926
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
    1
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      DOI: 10.7554/eLife.83004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
  44. May 2023
  45. www.biorxiv.org www.biorxiv.org
    Epigenetic reprogramming of imprinting at meiosis
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      DOI: 10.1101/2023.05.17.541143

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    biorxiv.org/content/10.1101/2023.05.17.541143v1
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    Methylated histones on mitotic chromosomes promote Topoisomerase IIα function for high fidelity chromosome segregation.
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    sciencedirect.com/science/article/pii/S2589004223008209
  47. Apr 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
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    sciencedirect.com/science/article/pii/S2211124723003911
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    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
    1
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      DOI: 10.1016/j.xcrm.2023.101006

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    sciencedirect.com/science/article/pii/S2666379123001167
  50. Mar 2023
  51. academic.oup.com academic.oup.com
    ATXN3 controls DNA replication and transcription by regulating chromatin structure
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      DOI: 10.1093/nar/gkad212

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad212/7086677
  52. europepmc.org europepmc.org
    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
    1
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      DOI: 10.1016/j.celrep.2023.112237

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    europepmc.org/article/med/36924502
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    A pair of readers of bivalent chromatin mediate formation of Polycomb-based “memory of cold” in plants
    1
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      DOI: 10.1016/j.molcel.2023.02.014

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    sciencedirect.com/science/article/pii/S109727652300117X
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    JMJ28 guides sequence-specific targeting of ATX1/2-containing COMPASS-like complex in Arabidopsis
    1
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      DOI: 10.1016/j.celrep.2023.112163

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    sciencedirect.com/science/article/pii/S2211124723001742
  55. Feb 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells
    1
    1. scibot 23 Feb 2023
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    Hypoxia induces transgenerational epigenetic inheritance of small RNAs
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    Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer
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  63. Nov 2022
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    Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
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    Polycomb-mediated repression of paternal chromosomes maintains haploid dosage in diploid embryos of Marchantia
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    Chromosome silencing in vitro reveals trisomy 21 causes cell-autonomous deficits in angiogenesis and early dysregulation in Notch signaling
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    Transcription factors TCF-1 and GATA3 are key factors for the epigenetic priming of early innate lymphoid progenitors toward distinct cell fates
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    Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
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    Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells
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    Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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    SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity
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    Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality
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    Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system
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    Collective regulation of chromatin modifications predicts replication timing during cell cycle
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo
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    Hybrid protein assembly-histone modification mechanism for PRC2-based epigenetic switching and memory
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    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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  158. Feb 2021
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    Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use
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    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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    Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin
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  162. Jan 2021
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    Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice
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    Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons
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  165. Dec 2020
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    Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency
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  167. Nov 2020
  168. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors
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  169. Sep 2020
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    The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators
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    Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation
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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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    Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin
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    Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells
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    A Dynamic Folded Hairpin Conformation Is Associated with α-Globin Activation in Erythroid Cells
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    Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits
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    Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development
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    PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway
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    Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity
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    Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
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    Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury
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    Chromatin Immunoprecipitation of Low Number of FACS-Purified Epidermal Cells
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  184. www.nature.com www.nature.com
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  186. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters
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    Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
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  188. Jan 2020
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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
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    H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis
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    Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells
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    Nucleome Dynamics during Retinal Development
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    The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma
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    Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells
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    CoBATCH for High-Throughput Single-Cell Epigenomic Profiling
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    Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung
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    Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression
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    ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures
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    Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms
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    PRC2-Associated Chromatin Contacts in the Developing Limb Reveal a Possible Mechanism for the Atypical Role of PRC2 in HoxA Gene Expression
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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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    The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf
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    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
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    DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency
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    DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
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    Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL‐Induced Osteoclastogenesis
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    Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
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    Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes
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    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress
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    Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia
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    A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
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    RNA-Dependent Epigenetic Silencing Directs Transcriptional Downregulation Caused by Intronic Repeat Expansions
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    Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development
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    Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation
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    Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
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