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Mar 2026
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p16High-expressing immune cells control disease tolerance as a defense and health span-extending strategy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.013
  
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sciencedirect.com/science/article/pii/S107476132600083X
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cardiomyocyte β-arrestins mediate inflammation and cGAS-STING activation in CVB3 viral myocarditis

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1. scibot 12 Feb 2026
  
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  DOI: 10.1152/ajpheart.00589.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12889003/
Jan 2026
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OPG-producing B Cells and RANKL-expressing T cells define immune signatures predictive of bone metastases in breast cancer

1
1. scibot 16 Jan 2026
  
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  DOI: 10.1158/2767-9764.CRC-25-0696
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12795788/
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Nat10-mediated ac4C epitranscriptomics orchestrates hematopoietic stem/progenitor cell fate determination via translation control

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1. scibot 15 Jan 2026
  
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  DOI: 10.1126/sciadv.ady0301
  
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science.org/doi/10.1126/sciadv.ady0301
54.241.53.176 54.241.53.176

lucero-et-al-2026-cardiomyocyte--arrestins-mediate-inflammation-and-cgas-sting-activation-in-cvb3-viral-myocarditis-html.html

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1. scibot 10 Jan 2026
  
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  DOI: 10.6084/m9.figshare.30598013
  
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54.241.53.176/230152961d72a3d5781220ef3dcdb60ea10cf9d0/lucero-et-al-2026-cardiomyocyte--arrestins-mediate-inflammation-and-cgas-sting-activation-in-cvb3-viral-myocarditis-html.html
Nov 2025
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MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.medj.2025.100936
  
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sciencedirect.com:5037/science/article/pii/S2666634025003630
Oct 2025
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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1. scibot 04 Oct 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
Sep 2025
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M1-like macrophages regulate T cell infiltration in colorectal cancer through P2X4 receptor

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113517
  
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sciencedirect.com/science/article/pii/S258900422501778X
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Directed-complement killing of Pseudomonas aeruginosa protects against lethal pneumonia

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1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.ebiom.2025.105926
  
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sciencedirect.com/science/article/pii/S2352396425003706
www.biorxiv.org www.biorxiv.org

Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis

1
1. scibot 10 Sep 2025
  
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  RRID:AB_312685
  
  DOI: 10.1101/2025.08.30.673054
  
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biorxiv.org/content/10.1101/2025.08.30.673054v1
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Gut microbiome profiling in Eµ-TCL1 mice reveals intestinal changes and a dysbiotic signature specific to chronic lymphocytic leukemia

1
1. scibot 19 Aug 2025
  
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  AB_312685
  
  DOI: 10.1158/2767-9764.CRC-25-0022
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12354945/
Jul 2025
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Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer

1
1. scibot 02 Jul 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.xcrm.2025.102211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12281435/
May 2025
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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

1
1. scibot 17 May 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2025.04.020
  
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sciencedirect.com/science/article/pii/S1074761325001839
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

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1. scibot 17 May 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2025.04.004
  
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sciencedirect.com/science/article/pii/S1074761325001670
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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

1
1. scibot 17 May 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.celrep.2025.115679
  
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sciencedirect.com/science/article/pii/S2211124725004504
Feb 2025
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Blockade of TSP-1/CD47 signal axis promotes donor hematopoietic engraftment by improving SEC/MK niche function

1
1. scibot 21 Feb 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.isci.2025.111952
  
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sciencedirect.com/science/article/pii/S2589004225002123
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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

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1. scibot 20 Feb 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.celrep.2025.115294
  
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sciencedirect.com/science/article/pii/S2211124725000658
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Divergent sex-specific pannexin-1 mechanisms in microglia and T cells underlie neuropathic pain

1
1. scibot 04 Feb 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.neuron.2025.01.005
  
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sciencedirect.com/science/article/pii/S0896627325000091
Jan 2025
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Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugates

1
1. scibot 23 Jan 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.ebiom.2025.105566
  
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sciencedirect.com/science/article/pii/S2352396425000106
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Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

1
1. scibot 23 Jan 2025
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.chom.2024.12.017
  
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sciencedirect.com/science/article/pii/S1931312824004840
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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1. scibot 24 Dec 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2024.11.021
  
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sciencedirect.com/science/article/pii/S1074761324005363
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Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin

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1. scibot 14 Dec 2024
  
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  AB_312685
  
  DOI: 10.1016/j.ccell.2024.11.013
  
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sciencedirect.com/science/article/pii/S1535610824004483
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

1
1. scibot 12 Dec 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.celrep.2024.115039
  
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sciencedirect.com/science/article/pii/S2211124724013901
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Modulating the immunodominance hierarchy of immunoglobulin germline-encoded structural motifs targeting the influenza hemagglutinin stem

1
1. scibot 02 Dec 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.celrep.2024.114990
  
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sciencedirect.com/science/article/pii/S221112472401341X
Sep 2024
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Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

1
1. scibot 25 Sep 2024
  
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  RRID:AB_469572
  
  DOI: 10.1016/j.immuni.2019.09.001
  
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sciencedirect.com/science/article/pii/S1074761319303723
Aug 2024
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Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.08.003
  
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sciencedirect.com/science/article/pii/S1534580724004866
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Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II

1
1. scibot 27 Aug 2024
  
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  AB_312685
  
  DOI: 10.1016/j.celrep.2024.114655
  
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sciencedirect.com/science/article/pii/S2211124724010064
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Baf155 controls hematopoietic differentiation and regeneration through chromatin priming

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1. scibot 01 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114558
  
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sciencedirect.com/science/article/pii/S2211124724008878
Jul 2024
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Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis

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1. scibot 24 Jul 2024
  
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  AB_312685
  
  DOI: 10.1016/j.isci.2024.110276
  
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sciencedirect.com/science/article/pii/S2589004224015013
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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

1
1. scibot 12 Jul 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.cmet.2024.06.010
  
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sciencedirect.com/science/article/pii/S1550413124002353
Jun 2024
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Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement

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1. scibot 06 Jun 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.xcrm.2024.101590
  
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sciencedirect.com/science/article/pii/S2666379124002829
May 2024
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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

2
1. scibot 31 May 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2024.05.006
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2024.05.006
  
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sciencedirect.com/science/article/pii/S1074761324002590
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Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression

1
1. scibot 30 May 2024
  
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  RRID:AB_312685
  
  DOI: 10.1016/j.immuni.2024.05.004
  
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sciencedirect.com/science/article/pii/S1074761324002553
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects

1
1. scibot 24 May 2024
  
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  RRID:AB_312685
  
  DOI: 10.1158/2767-9764.CRC-24-0071
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11110724/
Apr 2024
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Expression of a mutant CD47 protects against phagocytosis without inducing cell death or inhibiting angiogenesis

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Mar 2024
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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness

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Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells

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Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.

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Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies

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Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3

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PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652

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Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity

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Aug 2023
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Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis

1
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Chronic HDM exposure shows time-of-day and sex-based differences in inflammatory response associated with lung circadian clock disruption

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PTEN regulates hematopoietic lineage plasticity via PU.1-dependent chromatin accessibility

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Jul 2023
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Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury

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Jun 2023
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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

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Mar 2023
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

1
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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions

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Feb 2023
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Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

1
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Jan 2023
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Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

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Sep 2022
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cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells

1
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Jul 2022
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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells

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Mar 2022
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A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

1
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Tumor-derived Jagged1 promotes cancer progression through immune evasion

1
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Jan 2022
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SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models

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Dec 2021
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DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus

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Sep 2021
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Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling

1
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Aug 2021
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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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Jul 2021
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A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant

1
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May 2021
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Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation

1
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Apr 2021
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CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis

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Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

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Feb 2021
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Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

1
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Oct 2020
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Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety- and depressive-like behaviors

1
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Sep 2020
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Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation

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High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision

1
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  DOI: 10.1016/j.celrep.2020.108116
  
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Bmal1 integrates mitochondrial metabolism and macrophage activation

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  DOI: 10.7554/eLife.54090
  
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An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses

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  DOI: 10.1016/j.xcrm.2020.100035
  
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Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment

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  DOI: 10.1016/j.celrep.2019.12.034
  
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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  DOI: 10.1016/j.celrep.2019.09.065
  
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Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

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  DOI: 10.1016/j.immuni.2019.09.014
  
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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

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  DOI: 10.1016/j.cell.2019.07.044
  
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Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells

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The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

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  DOI: 10.1016/j.immuni.2018.12.018
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.12.024
  
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Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

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Untitled document

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Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

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Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

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Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch

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Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

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