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SIRT6-mediated immunometabolic reprogramming of macrophages drives neutrophilic asthma via LDHA-dependent glycolysis

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  DOI: 10.1016/j.celrep.2026.117294
  
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sciencedirect.com/science/article/pii/S2211124726003724
Feb 2026
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Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer progression via the Flo9-RadD interaction

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Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity

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  DOI: 10.1016/j.celrep.2026.116976
  
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sciencedirect.com/science/article/pii/S2211124726000549
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Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors

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  DOI: 10.1016/j.xcrm.2025.102545
  
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sciencedirect.com/science/article/pii/S2666379125006184
Jan 2026
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Immunoglobulin A-producing cells mediate the clinical benefits of metformin via interleukin-10

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  DOI: 10.1016/j.celrep.2025.116919
  
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Myeloid CD209 impairs T-cell activation by inducing ICAM-2–ERM–dependent cortical stiffening

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1. scibot 27 Jan 2026
  
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  DOI: 10.64898/2026.01.19.699861
  
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biorxiv.org/content/10.64898/2026.01.19.699861v1
Dec 2025
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Metformin hijacks AMPK-ERK1/2 signaling to trigger a pathogenic “selection trap” and thymic atrophy

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TIM-3 inhibition enhances breast tumor progression and metastasis: A paradoxical immune checkpoint response

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1. scibot 23 Dec 2025
  
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Potentiating immunotherapy in “immune-cold” solid tumors through orchestrating T cell immunity via tumor-specific genetic engineering

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  DOI: 10.1016/j.xcrm.2025.102510
  
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ssrn-5824364-html.html

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54.241.53.176/96b5a8207be73c5a7cbd506ff76bd6eccd66fbbb/ssrn-5824364-html.html
Oct 2025
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Protocol for measuring cellular energetics through noncanonical amino acid tagging in human peripheral blood and murine tissue immune cells

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  DOI: 10.1016/j.xpro.2025.104134
  
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sciencedirect.com/science/article/pii/S2666166725005404
Sep 2025
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TIM-3 ameliorates host responses to Salmonella infection by controlling iron driven CD4+ T cell differentiation and interleukin-10 formation

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.ebiom.2025.105910
  
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sciencedirect.com/science/article/pii/S2352396425003548
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Evolution of a melanoma that escapes allogeneic rejection

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116288
  
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sciencedirect.com/science/article/pii/S2211124725010599
Aug 2025
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TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

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1. scibot 19 Aug 2025
  
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  DOI: 10.1186/s13046-025-03513-5
  
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jeccr.biomedcentral.com/articles/10.1186/s13046-025-03513-5
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Stress-induced glucocorticoids enhance acute inflammation by promoting the differentiation of Th17 cells

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1. scibot 05 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116093
  
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sciencedirect.com/science/article/pii/S2211124725008642
Jul 2025
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Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.07.004
  
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sciencedirect.com/science/article/pii/S0092867425007937
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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sciencedirect.com/science/article/pii/S1074761325002808
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Activity-attenuated serum albumin-fused interleukin-33 suppresses experimental autoimmune encephalomyelitis

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102231
  
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Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in vivo CAR-T therapy for inflamm-aging

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1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102209
  
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Jun 2025
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An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia

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  DOI: 10.1158/2767-9764.CRC-25-0023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
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Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis

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  DOI: 10.1016/j.jep.2025.120184
  
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May 2025
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Cancer vaccine from intracellularly gelated tumor cells functionalized with CD47 blockage and damage-associated molecular pattern exposure

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  DOI: 10.1016/j.xcrm.2025.102092
  
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Apr 2025
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Inhibition of EMT driver PTK6 enhances anti-tumor immune responses against triple-negative breast cancer

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  DOI: 10.1101/2025.01.11.632044
  
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biorxiv.org/content/10.1101/2025.01.11.632044v1
Feb 2025
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Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses

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pmc.ncbi.nlm.nih.gov/articles/PMC11970324/
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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  DOI: 10.1016/j.ccell.2025.01.004
  
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sciencedirect.com/science/article/pii/S1535610825000224
Jan 2025
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A subunit vaccine Ag85A-LpqH focusing on humoral immunity provides substantial protection against tuberculosis in mice

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1. scibot 09 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111568
  
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Dec 2024
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A double-edged sword role of IFN-γ producing iNKT cells in sepsis: persistent suppression of Treg cell formation in a Nr4a1 dependent manner

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111462
  
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Nov 2024
52.53.155.43 52.53.155.43

can-24-1817-html.html

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  DOI: 10.1158/0008-5472.can-24-1817
  
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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Sep 2024
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Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

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  DOI: 10.1084/jem.20231835
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10965393/
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PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

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  DOI: 10.1016/j.ymthe.2024.05.038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405166/
Aug 2024
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Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis

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  DOI: 10.1016/j.chom.2024.07.028
  
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sciencedirect.com/science/article/pii/S1931312824002877
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Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

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  DOI: 10.1016/j.cmet.2024.07.017
  
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sciencedirect.com/science/article/pii/S1550413124002882
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Baf155 controls hematopoietic differentiation and regeneration through chromatin priming

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  DOI: 10.1016/j.celrep.2024.114558
  
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Jul 2024
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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114532
  
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Jun 2024
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Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement

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  DOI: 10.1016/j.xcrm.2024.101590
  
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sciencedirect.com/science/article/pii/S2666379124002829
May 2024
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Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy

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1. scibot 09 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.015
  
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The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor

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Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21

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Mar 2024
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Nanodrug-bacteria conjugates-mediated oncogenic collagen depletion enhances immune checkpoint blockade therapy against pancreatic cancer

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S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function

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FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment

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Feb 2024
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Alleviation of monocyte exhaustion by BCG derivative mycolic acid

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Xist ribonucleoproteins promote female sex-biased autoimmunity

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Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics

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CD62L expression marks a functionally distinct subset of memory B cells

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Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition

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Nov 2023
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Lactobacillus acidophilus-derived indole lactic acid reverses colitis susceptibility in cesarean-born offspring via activation of AhR

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Jun 2023
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Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

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Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma

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Protocol for analyzing transforming growth factor β signaling in dextran-sulfate-sodium-induced colitic mice using flow cytometry and western blotting

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Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response

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Aug 2022
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Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance

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Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway

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B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation

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The immunometabolite S-2-hydroxyglutarate exacerbates perioperative ischemic brain injury and cognitive dysfunction by enhancing CD8+ T lymphocyte-mediated neurotoxicity

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link.springer.com/article/10.1186/s12974-022-02537-4
Jun 2022
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Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils

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Translocator Protein Ligand Etifoxine Attenuates MPTP-Induced Neurotoxicity

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  DOI: 10.3389/fnmol.2022.850904
  
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frontiersin.org/article/10.3389/fnmol.2022.850904/full
Apr 2022
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mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment

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  DOI: 10.1158/1541-7786.MCR-20-0799
  
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aacrjournals.org/mcr/article/19/4/717/672854/mDKN-01-a-Novel-Anti-DKK1-mAb-Enhances-Innate
Mar 2022
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Distinct hepatic immunological patterns are associated with the progression or inhibition of hepatocellular carcinoma

1
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Jan 2022
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CXCR3 regulates stem and proliferative CD8+ T cells during chronic infection by promoting interactions with DCs in splenic bridging channels

1
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Nov 2021
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Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice

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Aug 2021
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Loss of Zbtb32 in NOD mice does not significantly alter T cell responses.

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  DOI: 10.12688/f1000research.13864.2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5909056/
Jul 2021
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Loss of Zbtb32 in NOD mice does not significantly alter T cell responses.

3
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  DOI: 10.12688/f1000research.13864.1
  
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May 2021
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Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing

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  DOI: 10.1016/j.stem.2021.04.003
  
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Feb 2021
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Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

1
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  DOI: 10.1016/j.ccell.2020.08.001
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
Nov 2020
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Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection

1
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  DOI: 10.1016/j.medj.2020.10.004
  
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Complement C4A Regulates Autoreactive B Cells in Murine Lupus

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Sep 2020
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Heparin affects the induction of regulatory T cells independent of anticoagulant activity and suppresses the allogeneic immune responses

1
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  DOI: 10.1111/cei.13480
  
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Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development

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  DOI: 10.1016/j.celrep.2020.107802
  
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Jan 2020
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Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses

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  DOI: 10.1016/j.immuni.2019.06.007
  
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sciencedirect.com/science/article/pii/S1074761319302778
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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_312690
  
  DOI: 10.1016/j.celrep.2019.05.020
  
  Resource: (BioLegend Cat# 100405, RRID:AB_312690)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_312690
  
  What is this?
  
  RRID:AB_312690 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_312690

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scibot

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sciencedirect.com/science/article/pii/S221112471930631X
Nov 2018
www.sciencedirect.com www.sciencedirect.com

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_312690
  
  Curator: @Jmenke
  
  Resource used:
  
  (BioLegend Cat# 100405, RRID:AB_312690)
  
  SciCrunch record: RRID:AB_312690
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_312690 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_312690

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scibot

URL

sciencedirect.com/science/article/pii/S0092867418311711

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