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Cell intrinsic heme synthesis is required for the proper activation of naive CD4+ T cells

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  DOI: 10.1016/j.isci.2026.118114
  
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sciencedirect.com/science/article/pii/S2589004226034978
Sep 2026
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Albumin uptake through FcRn promotes tumor-associated macrophage maturation and albumin-bound immunotherapy response

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  DOI: 10.1016/j.celrep.2026.118010
  
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sciencedirect.com/science/article/pii/S2211124726010880
Jun 2026
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Trans-presentation of IL-6Rα by macrophages drives colorectal cancer development

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sciencedirect.com/science/article/pii/S2211124726006273
May 2026
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Targeted protein degradation via chimeric antigen receptor (CAR)-mediated antigen endocytosis in T cells

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.hlife.2026.05.003
  
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sciencedirect.com/science/article/pii/S2949928326000313
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VSIG4 restricts hepatocellular carcinoma control by suppressing tumor-specific CD8+ T cell immunity in the tumor microenvironment

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  DOI: 10.1158/2326-6066.CIR-25-0836
  
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aacrjournals.org/cancerimmunolres/article/14/5/718/784454/VSIG4-Restricts-Hepatocellular-Carcinoma-Control
Mar 2026
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Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer

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1. scibot 20 Mar 2026
  
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sciencedirect.com/science/article/pii/S2666379126000777
Feb 2026
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Protocol for intranuclear Nrf2 detection in activated mouse, human, and Jurkat T cells by spectral flow cytometry

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1. scibot 21 Feb 2026
  
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  DOI: 10.1016/j.xpro.2026.104360
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12915187/
Jan 2026
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1-s2.0-S2589004225028330-main-html.html

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54.241.53.176/ad3fb92c7e3a93bdd68e851159cb5afcddddbde8/1-s2.0-S2589004225028330-main-html.html
Sep 2025
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IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.08.017
  
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sciencedirect.com/science/article/pii/S0092867425009729
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GD2TIF cells as a platform for single-dose and long-term delivery of biologics

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  DOI: 10.1038/s41467-025-63427-w
  
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nature.com/articles/s41467-025-63427-w
Aug 2025
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A vascular-associated fibroblastic cell controls pancreatic islet immunity

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1. scibot 29 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116189
  
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sciencedirect.com/science/article/pii/S221112472500960X
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Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116177
  
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sciencedirect.com/science/article/pii/S2211124725009489
Jul 2025
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KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.011
  
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sciencedirect.com/science/article/pii/S1535610825002612
Jun 2025
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An RNA vaccine against adrenomedullin reduces angiogenesis and tumor burden in a syngeneic metastatic melanoma mouse model

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  DOI: 10.3389/fimmu.2025.1604156
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12176902/
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Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression

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  DOI: 10.1016/j.celrep.2025.115866
  
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sciencedirect.com/science/article/pii/S2211124725006370
May 2025
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Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115733
  
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sciencedirect.com/science/article/pii/S2211124725005042
Apr 2025
52.53.155.43 52.53.155.43

PD-html.html

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  DOI: 10.1101/2025.03.25.645270
  
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52.53.155.43/639914d725a708fad2e0783fbcce6b5221fc6f0d/PD-html.html
Feb 2025
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An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101981
  
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sciencedirect.com/science/article/pii/S2666379125000540
Jan 2025
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MFGE8 induces anti-PD-1 therapy resistance by promoting extracellular vesicle sorting of PD-L1

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  DOI: 10.1016/j.xcrm.2024.101922
  
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sciencedirect.com/science/article/pii/S2666379124006931
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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  DOI: 10.1016/j.immuni.2024.11.021
  
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sciencedirect.com/science/article/pii/S1074761324005363
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Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin

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  DOI: 10.1016/j.ccell.2024.11.013
  
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sciencedirect.com/science/article/pii/S1535610824004483
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A yeast-based oral therapeutic delivers immune checkpoint inhibitors to reduce intestinal tumor burden

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  DOI: 10.1016/j.chembiol.2024.10.013
  
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sciencedirect.com/science/article/pii/S2451945624004525
Aug 2023
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A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection

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1. scibot 31 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107552
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10460994/
Jun 2023
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Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

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1. scibot 24 Jun 2023
  
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  DOI: 10.7554/eLife.83004
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
Apr 2023
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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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  DOI: 10.1016/j.celrep.2023.112314
  
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sciencedirect.com/science/article/pii/S221112472300325X
Mar 2023
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Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery

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  DOI: 10.1016/j.isci.2023.106341
  
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sciencedirect.com/science/article/pii/S2589004223004182
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

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  DOI: 10.1016/j.ccell.2023.02.005
  
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sciencedirect.com/science/article/pii/S1535610823000338
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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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1. scibot 09 Mar 2023
  
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  DOI: 10.1126/sciimmunol.add8005
  
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science.org/doi/10.1126/sciimmunol.add8005
Jan 2023
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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

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  DOI: 10.1016/j.isci.2022.105726
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9721160/
May 2022
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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

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  DOI: 10.1016/j.celrep.2022.110814
  
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sciencedirect.com/science/article/pii/S221112472200585X
Mar 2022
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Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation

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  DOI: 10.1016/j.celrep.2022.110564
  
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sciencedirect.com/science/article/pii/S2211124722003084
Jan 2022
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SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models

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  DOI: 10.1002/cti2.1364
  
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onlinelibrary.wiley.com/doi/10.1002/cti2.1364
Dec 2021
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CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture

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1. scibot 29 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103603
  
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sciencedirect.com/science/article/pii/S258900422101573X
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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.immuni.2021.11.004
  
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sciencedirect.com/science/article/pii/S1074761321004957
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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

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1. scibot 07 Dec 2021
  
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  DOI: 10.1016/j.cell.2021.11.018
  
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sciencedirect.com/science/article/pii/S0092867421013337
Oct 2021
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Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

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Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon

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1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.014
  
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Untitled document

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  DOI: 10.1016/j.celrep.2018.10.042
  
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Untitled document

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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.054
  
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T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

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1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.cell.2018.10.008
  
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Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

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May 2021
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Production of the Cytokine VEGF-A by CD4+ T and Myeloid Cells Disrupts the Corneal Nerve Landscape and Promotes Herpes Stromal Keratitis

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Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

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Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity

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Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

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1. scibot 27 Feb 2021
  
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Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

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1. scibot 21 Nov 2020
  
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Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety- and depressive-like behaviors

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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

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Nov 2018
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Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells

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1. scibot 05 Nov 2018
  
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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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1. scibot 05 Nov 2018
  
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