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Activated T cells degrade extracellular proteins to enhance effector functions

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1. scibot 25 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116797
  
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sciencedirect.com/science/article/pii/S2211124725015694
Sep 2025
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Mitochondrial-activity-driven hematopoietic stem cell fate and lineage choice is first established in the aorta-gonad-mesonephros

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1. scibot 19 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116296
  
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sciencedirect.com/science/article/pii/S2211124725010678
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A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.08.015
  
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sciencedirect.com/science/article/pii/S1074761325003784
Aug 2025
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Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates pancreatic ductal adenocarcinoma development

1
1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.cmet.2025.07.008
  
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sciencedirect.com/science/article/pii/S1550413125003353
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia

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1. scibot 25 Jun 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
May 2025
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Indole-3-lactic acid suppresses colorectal cancer via metabolic reprogramming

1
1. scibot 31 May 2025
  
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  DOI: 10.1080/19490976.2025.2508949
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12118437/
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Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms

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1. scibot 20 May 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0545
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617599/
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.03.036
  
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sciencedirect.com/science/article/pii/S1535610825001370
Apr 2025
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METTL3 promotes an immunosuppressive microenvironment in bladder cancer via m6A-dependent CXCL5/CCL5 regulation

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1. scibot 19 Apr 2025
  
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  DOI: 10.1136/jitc-2024-011108
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12001370/
Mar 2025
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PDF-html.html

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1. scibot 24 Mar 2025
  
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52.53.155.43/089c935c8b8375c73eca3bfe64a1d2170a0cdb88/PDF-html.html
Feb 2025
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Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses

1
1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101976
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970324/
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Cryoablation does not significantly contribute to systemic effector immune responses in poorly immunogenic B16F10 melanoma model

1
1. scibot 13 Feb 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-0371
  
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aacrjournals.org/clincancerres/article/30/18/4190/747463/Cryoablation-Does-Not-Significantly-Contribute-to
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In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313

1
1. scibot 06 Feb 2025
  
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  RRID:AB_312746
  
  DOI: 10.1016/j.immuni.2025.01.009
  
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sciencedirect.com/science/article/pii/S1074761325000342
Jan 2025
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Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation

1
1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115127
  
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sciencedirect.com/science/article/pii/S2211124724014785
Dec 2024
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Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101877
  
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sciencedirect.com/science/article/pii/S2666379124006487
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Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells

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1. scibot 20 Dec 2024
  
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  AB_312746
  
  DOI: 10.1126/scisignal.adi8753
  
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science.org/doi/10.1126/scisignal.adi8753
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Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

1
1. scibot 10 Dec 2024
  
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  RRID:AB_312746
  
  DOI: 10.1016/j.immuni.2024.11.008
  
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sciencedirect.com/science/article/pii/S1074761324005235
Nov 2024
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can-24-1817-html.html

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1. scibot 14 Nov 2024
  
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  AB_312746
  
  DOI: 10.1158/0008-5472.can-24-1817
  
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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Sep 2024
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Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.008
  
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sciencedirect.com/science/article/pii/S1535610824003076
Jul 2024
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Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114425
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00754-X
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Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101648
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
Apr 2024
www.embopress.org www.embopress.org

The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor

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1. scibot 25 Apr 2024
  
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  DOI: 10.1038/s44321-024-00051-z
  
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embopress.org/doi/full/10.1038/s44321-024-00051-z
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Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21

1
1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114095
  
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sciencedirect.com/science/article/pii/S2211124724004236
Feb 2024
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Chronic stress alters lipid mediator profiles associated with immune-related gene expressions and cell compositions in mouse bone marrow and spleen

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.jphs.2024.02.010
  
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sciencedirect.com/science/article/pii/S1347861324000215
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche

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1. scibot 07 Feb 2024
  
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  DOI: 10.1038/s41467-024-45471-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844594/
Jan 2024
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A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity

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1. scibot 12 Jan 2024
  
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  DOI: 10.1016/j.molcel.2023.12.015
  
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sciencedirect.com/science/article/pii/S1097276523010341
52.53.155.43 52.53.155.43

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors

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1. scibot 10 Jan 2024
  
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  RRID:AB_312746
  
  DOI: 10.1126/sciimmunol.abq2424
  
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52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
Nov 2023
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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses

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1. scibot 18 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108348
  
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sciencedirect.com/science/article/pii/S2589004223024252
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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.devcel.2023.10.010
  
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sciencedirect.com/science/article/pii/S1534580723005518
Aug 2023
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S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113006
  
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sciencedirect.com/science/article/pii/S2211124723010173
52.53.155.43 52.53.155.43

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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1. scibot 17 Aug 2023
  
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  RRID:AB_312746
  
  DOI: 10.1016/j.celrep.2023.112944
  
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2. scibot 11 Aug 2023
  
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  RRID:AB_312746
  
  DOI: 10.1016/j.celrep.2023.112944
  
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52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
Jul 2023
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Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112864
  
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sciencedirect.com/science/article/pii/S2211124723008756
Apr 2023
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Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir

1
1. scibot 20 Apr 2023
  
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  RRID:AB_312746
  
  DOI: 10.1016/j.immuni.2023.01.032
  
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sciencedirect.com/science/article/pii/S1074761323000444
Nov 2022
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Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning

1
1. scibot 09 Nov 2022
  
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  RRID:AB_312746
  
  DOI: 10.1016/j.celrep.2022.111615
  
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sciencedirect.com/science/article/pii/S221112472201484X
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens

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Jun 2022
52.53.155.43 52.53.155.43

1-s2.0-S1875536422601602-main-html.html

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  AB_312746
  
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Mar 2022
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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cells

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Jan 2022
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ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

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Sep 2021
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Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes

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Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response

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Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection

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Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection

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Untitled document

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May 2021
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The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation

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HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

1
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Feb 2021
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Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
Dec 2020
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Cnp Promoter-Driven Sustained ERK1/2 Activation Increases B-Cell Activation and Suppresses Experimental Autoimmune Encephalomyelitis - Marisa A. Jeffries, Alison E. Obr, Kelly Urbanek, Sharyl L. Fyffe-Maricich, Teresa L. Wood, 2020

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Nov 2020
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Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection

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Localized hydrogel delivery of dendritic cells for attenuation of multiple sclerosis in a murine model

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onlinelibrary.wiley.com/doi/10.1002/jbm.a.37118
Sep 2020
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HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

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Jan 2020
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Brief exposure to hyperglycemia activates dendritic cells in vitro and in vivo

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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

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Untitled document

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sciencedirect.com/science/article/pii/S2211124719300348
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Untitled document

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Untitled document

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The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

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Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance

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