134 Matching Annotations
  1. Last 7 days
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    Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine
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    sciencedirect.com/science/article/pii/S2666379124006487
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    Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet
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    sciencedirect.com/science/article/pii/S1934590924004132
  4. Nov 2024
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    Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer
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    sciencedirect.com/science/article/pii/S0092867424012595
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11536043/
  7. Sep 2024
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    CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway
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  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION
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    ncbi.nlm.nih.gov/pmc/articles/PMC11382997/
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    sciencedirect.com/science/article/pii/S1550413117306186
  13. Jul 2024
  14. www.cell.com www.cell.com
    Nynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00215-7
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomineralization-inspired synthesis of autologous cancer vaccines for personalized metallo-immunotherapy
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    GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development
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    cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
  17. Jun 2024
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    Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement
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  19. www.nature.com www.nature.com
    A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice
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    nature.com/articles/s41590-024-01834-9
  20. May 2024
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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  22. 52.53.155.43 52.53.155.43
    Sufficient Water Intake Maintains the Gut Microbiota and Immune Homeostasis and Promotes Pathogen Elimination
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  23. Apr 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection
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    XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
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    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
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    sciencedirect.com/science/article/pii/S2211124724003693
  27. Mar 2024
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    Derivation of functional thymic epithelial organoid lines from adult murine thymus
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    sciencedirect.com/science/article/pii/S2211124724003474
  29. Feb 2024
  30. www.mdpi.com www.mdpi.com
    The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model
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    mdpi.com/1422-0067/25/3/1880
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alleviation of monocyte exhaustion by BCG derivative mycolic acid
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    ncbi.nlm.nih.gov/pmc/articles/PMC10845070/
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    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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    sciencedirect.com/science/article/pii/S2451945624000382
  33. Jan 2024
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    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
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    A time- and single-cell-resolved model of murine bone marrow hematopoiesis
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    sciencedirect.com/science/article/pii/S1934590923004319
  36. Nov 2023
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    The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions
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    sciencedirect.com/science/article/pii/S153561082300363X
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    Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses
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    sciencedirect.com/science/article/pii/S2589004223024252
  39. www.biorxiv.org www.biorxiv.org
    One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice
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    biorxiv.org/content/10.1101/2023.11.06.565713v1
  40. Oct 2023
  41. www.embopress.org www.embopress.org
    Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis
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    embopress.org/doi/10.15252/embr.202357653
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of the CD8+ T cell immune response in mice infected with OVA-Listeriamonocytogenes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10550835/
  43. Sep 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Low dietary fiber intake impairs small intestinal Th17 and intraepithelial T cell development over generations
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  45. Aug 2023
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    Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity
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    sciencedirect.com/science/article/pii/S240584402306423X
  47. Jul 2023
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    An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression
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    sciencedirect.com/science/article/abs/pii/S1074761323002698
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    CCL21-Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth
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    onlinelibrary.wiley.com/doi/10.1111/cas.15902
  50. Jun 2023
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    Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s
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    Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow
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    sciencedirect.com/science/article/pii/S2211124723005910
  53. www.sciencedirect.com www.sciencedirect.com
    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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    sciencedirect.com/science/article/pii/S1535610823001733
  54. May 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunity
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    sciencedirect.com/science/article/pii/S2211124723005600
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    Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer
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    sciencedirect.com/science/article/pii/S153561082300137X
  57. Apr 2023
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    T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection
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    sciencedirect.com/science/article/pii/S2211124723004187
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    NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection
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  61. Mar 2023
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    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
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    Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow
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  64. Feb 2023
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    Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes
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    Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer
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    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
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  69. Dec 2022
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  71. Nov 2022
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    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
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    Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN
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  75. Oct 2022
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    Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells
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  77. Sep 2022
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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    Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination
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  93. Apr 2022
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    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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    Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
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    Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection
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  114. Jul 2021
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    A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus
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  117. Jun 2021
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    A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection
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  119. May 2021
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    The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth
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    Resident memory T cells in tumor-distant tissues fortify against metastasis formation
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    A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  125. Apr 2021
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    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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  137. Jan 2021
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  139. Nov 2020
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    Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity
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  142. Oct 2020
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    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
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  144. Sep 2020
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
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  151. Jan 2020
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    Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses
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    IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection
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    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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    HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
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    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression
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    Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment
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    The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation
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    Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity
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    Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation
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    Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
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    Induction of Live Cell Phagocytosis by a Specific Combination of Inflammatory Stimuli
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