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IL7R mRNA therapy enhances antitumor T cell immunity and suppresses tumor growth in preclinical tumor models

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1. scibot 15 Oct 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13647033/
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Orally delivered metabolically reprogrammed probiotics for cascade-activated antitumor immunity in colorectal cancer

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1. scibot 15 Oct 2026
  
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  DOI: 10.1016/j.xcrm.2026.103111
  
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sciencedirect.com/science/article/pii/S2666379126005288
Oct 2026
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LPL-Positive Endothelial Cells Control T-cell Homing in Liver Metastasis

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1. scibot 12 Oct 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13628096/
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A developmentally restricted γδ T cell-IL-17A axis supports mouse heart regeneration

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1. scibot 09 Oct 2026
  
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  DOI: 10.1016/j.celrep.2026.118100
  
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Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression

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1. scibot 01 Oct 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13623212/
Sep 2026
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CD4 T cells convert transient responses to KRAS inhibition to durable remissions in pancreatic cancer

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1. scibot 27 Sep 2026
  
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NAD+ precursor treatment prevents cardiomyopathy but disrupts erythroid maturation in mitochondrial progeria

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1. scibot 01 Sep 2026
  
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Aug 2026
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Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression

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1. scibot 31 Aug 2026
  
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Metabolic Immunosuppression Mediated by Proliferative CD168+ TAMs in Colon Cancer

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1. scibot 27 Aug 2026
  
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  DOI: 10.1101/2025.09.02.673578
  
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54.241.53.176/296e6152a2930ab6024c6cc56722776ee091321b/2025.09.02.673578.full-html.html
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Biophysical reprogramming of immunosuppressive neutrophils by cold atmospheric plasma reinvigorates antitumor immunity

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1. scibot 13 Aug 2026
  
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  DOI: 10.1126/sciadv.aee2483
  
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science.org/doi/10.1126/sciadv.aee2483
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Biophysical reprogramming of immunosuppressive neutrophils by cold atmospheric plasma reinvigorates antitumor immunity

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1. scibot 08 Aug 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13440387/
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Universal catalytic endothelial lineage nanovesicles for targeting and rescuing ischemic endothelium

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1. scibot 07 Aug 2026
  
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  DOI: 10.1016/j.xcrm.2026.102972
  
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ATP-Red enables single-cell bioenergetic phenotyping by flow cytometry

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1. scibot 01 Aug 2026
  
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  DOI: 10.1016/j.crmeth.2026.101537
  
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sciencedirect.com/science/article/pii/S2667237526002389
Jul 2026
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Combination of exosome vaccines, lenvatinib, and anti-PD-1 eradicates tumor in autochthonous hepatocellular carcinoma mice

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1. scibot 25 Jul 2026
  
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  DOI: 10.1016/j.xcrm.2026.102933
  
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Septin7 is essential in early hematopoiesis, but redundant at later stages

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1. scibot 17 Jul 2026
  
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  DOI: 10.26508/lsa.202603637
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13365248/
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Targeting cholesterol esterification sensitizes liver cancer to CD8+ T cell attack by impairing metabolic and redox resilience

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1. scibot 07 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.002
  
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sciencedirect.com/science/article/pii/S1074761326002530
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LEF1 and niche factors determine T cell stemness across chronic diseases

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1. scibot 04 Jul 2026
  
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  DOI: 10.1016/j.cell.2026.06.022
  
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sciencedirect.com/science/article/pii/S0092867426007099
Jun 2026
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Reprogramming bacterial energetics reverses lactate-mediated immunosuppression for synergistic cancer immunotherapy

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1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.tibtech.2026.05.021
  
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sciencedirect.com/science/article/pii/S0167779926002349
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VEGFR2 inhibition potentiates STING-mediated antitumor immunity

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1. scibot 22 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117576
  
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The gut microbiota directs vitamin A flux to regulate intestinal T cell development

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1. scibot 21 Jun 2026
  
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  DOI: 10.1016/j.chom.2026.05.019
  
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Enhancing Immunotherapeutic Response in Colorectal Cancer with a Neuropilin-1-Targeting Tumor-Penetrating Peptide

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1. scibot 13 Jun 2026
  
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  DOI: 10.1158/2767-9764.CRC-25-0619
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13250810/
May 2026
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Targeting EP2/EP4-driven expansion of suppressive VSIG4high macrophages overcomes immunotherapy resistance in colorectal cancer

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1. scibot 30 May 2026
  
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Targeted protein degradation via chimeric antigen receptor (CAR)-mediated antigen endocytosis in T cells

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1. scibot 22 May 2026
  
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Dendritic cell redundancy enables priming of anti-tumor CD4+ T cells in pancreatic cancer

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.005
  
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MicroRNA-146a protects against hepatocellular carcinoma through suppression of CCL5

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1. scibot 06 May 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13138226/
Apr 2026
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MMRN1-EGFR drives sialylglycan-Siglec immune evasion in AML leukemia stem cells

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.stem.2026.03.012
  
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Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0649
  
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aacrjournals.org/cancerdiscovery/article/16/1/155/771238/Activation-of-T-Cell-Intrinsic-p53-by-Acetylation
Mar 2026
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Engineered MSCs enable bone marrow-targeted immunomodulation

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.03.003
  
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Collagen-bearing exosomes from breast cancer-associated fibroblasts promote T cell dysfunction

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1. scibot 26 Mar 2026
  
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  DOI: 10.1158/2767-9764.CRC-25-0259
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13012019/
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Insufficient erythrocyte-derived S1P: A pathogenic driver and diagnostic biolipid for tumor progression

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1. scibot 24 Mar 2026
  
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Ether phospholipids modulate somatosensory responses by tuning multiple receptor functions in Drosophila

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115209
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13018890/
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TCR-NF-κB signaling activates the SENP1-NR4A1 axis to fine-tune effector activation of CD8+ T cells

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117102
  
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Hematopoietic stem cells activate a latent differentiation pathway to facilitate recovery after 5-fluorouracil-induced myeloablation

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1. scibot 03 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.003
  
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Feb 2026
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Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.chembiol.2026.02.001
  
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Therapeutic Effect of Gemcitabine Combined With Angelica Polysaccharide on Triple Negative Breast Cancer in Mice

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1. scibot 19 Feb 2026
  
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  DOI: 10.1177/15347354251414897
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12909758/
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Bacterial vesicles from intratumoral L. salivarius enhance PD-1 blockade via FPR1-mediated macrophage polarization in gastric cancer

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102621
  
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Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition

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IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma

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Loss of EHMT2 enhances NK cell-driven anti-tumor immunity through TGF-β1 suppression

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Uridine depletion impairs CD8⁺ T cell antitumor activity through N-glycosylation

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Dec 2025
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Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

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The TCR-SUB1-DOCK2 axis promotes autoimmunity by driving pathogenic CD4+ T cell tissue infiltration

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MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors

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Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells

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Adoptive transfer of TregIL-33 cells ameliorates acute graft-versus-host disease by regulating the HPGD/PGE2 pathway

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Oct 2025
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NKp46 Recognizes the Hyphal Form of Candida albicans and Mediates Protective Antifungal Immunity

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Sep 2025
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RSK1 reprograms the ubiquitin pathway to promote immune suppression

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1-s2.0-S2589004225018176-main-html.html

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Aug 2025
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Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity

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Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombination

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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment

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Jun 2025
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VISTA immune checkpoint blunts radiotherapy-induced antitumor immune response

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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency

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Nociceptor-derived CGRP enhances dermal type I conventional dendritic cell function to drive autoreactive CD8+ T cell responses in vitiligo

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KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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Ocular immune privilege in action: The living eye imposes unique regulatory and anergic gene signatures on uveitogenic T cells

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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

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Myeloid-lineage-specific membrane protein LRRC25 suppresses immunity in solid tumor and is a potential cancer immunotherapy checkpoint target

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Enteric neuronal Piezo1 maintains mechanical and immunological homeostasis by sensing force

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Feb 2025
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The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments

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OAS cross-activates RNase L intercellularly through cell-to-cell transfer of 2-5A to spread innate immunity

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An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment

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Jan 2025
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MFGE8 induces anti-PD-1 therapy resistance by promoting extracellular vesicle sorting of PD-L1

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Postprandial parasympathetic signals promote lung type 2 immunity

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  DOI: 10.1016/j.neuron.2024.12.020
  
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1-s2.0-S2589004225000641-main-html.html

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Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation

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Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine

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Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet

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  DOI: 10.1016/j.stem.2024.11.014
  
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Nov 2024
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Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer

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  DOI: 10.1016/j.cell.2024.10.042
  
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Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis

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  DOI: 10.1016/j.isci.2024.111144
  
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Sep 2024
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CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway

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  DOI: 10.1016/j.xgen.2024.100659
  
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TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION

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Aug 2024
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Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance

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  DOI: 10.1016/j.xcrm.2024.101686
  
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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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  DOI: 10.1016/j.cmet.2017.10.006
  
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Jul 2024
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Nynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening

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  DOI: 10.1016/j.stem.2024.06.007
  
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Biomineralization-inspired synthesis of autologous cancer vaccines for personalized metallo-immunotherapy

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GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development

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  DOI: 10.1016/j.devcel.2024.06.007
  
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cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
Jun 2024
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Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement

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A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice

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  DOI: 10.1038/s41590-024-01834-9
  
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May 2024
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

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  DOI: 10.1016/j.cell.2024.04.023
  
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52.53.155.43 52.53.155.43

Sufficient Water Intake Maintains the Gut Microbiota and Immune Homeostasis and Promotes Pathogen Elimination

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Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection

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XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies

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Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

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  DOI: 10.1016/j.celrep.2024.114041
  
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Mar 2024
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Derivation of functional thymic epithelial organoid lines from adult murine thymus

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  DOI: 10.1016/j.celrep.2024.114019
  
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Feb 2024
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The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model

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  DOI: 10.3390/ijms25031880
  
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Alleviation of monocyte exhaustion by BCG derivative mycolic acid

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Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor

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  DOI: 10.1016/j.chembiol.2024.01.002
  
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Jan 2024
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Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity

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  DOI: 10.1016/j.cmet.2023.12.016
  
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A time- and single-cell-resolved model of murine bone marrow hematopoiesis

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  DOI: 10.1016/j.stem.2023.12.001
  
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Nov 2023
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The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions

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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses

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  DOI: 10.1016/j.isci.2023.108348
  
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One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice

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  DOI: 10.1101/2023.11.06.565713
  
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biorxiv.org/content/10.1101/2023.11.06.565713v1
Oct 2023
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Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis

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  DOI: 10.15252/embr.202357653
  
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Detection of the CD8+ T cell immune response in mice infected with OVA-Listeriamonocytogenes

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  DOI: 10.1016/j.xpro.2023.102582
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10550835/
Sep 2023
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Low dietary fiber intake impairs small intestinal Th17 and intraepithelial T cell development over generations

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  DOI: 10.1016/j.celrep.2023.113140
  
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Aug 2023
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Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity

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  DOI: 10.1016/j.heliyon.2023.e19215
  
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Jul 2023
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An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression

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onlinelibrary.wiley.com onlinelibrary.wiley.com

CCL21-Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth

1
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  DOI: 10.1111/cas.15902
  
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onlinelibrary.wiley.com/doi/10.1111/cas.15902
Jun 2023
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Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s

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  DOI: 10.1016/j.celrep.2023.112610
  
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Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow

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  DOI: 10.1016/j.celrep.2023.112580
  
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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

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  DOI: 10.1016/j.ccell.2023.05.005
  
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sciencedirect.com/science/article/pii/S1535610823001733
May 2023
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Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunity

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  DOI: 10.1016/j.celrep.2023.112549
  
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Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer

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T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

1
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NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection

1
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SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology

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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

1
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Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow

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TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state

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Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

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Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer

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IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment

1
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Immunostaining of tumor-infiltrating immune-cell-related markers and cytokines in the tumor fractional radiation model of host PD-L1-deficient mice

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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

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Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN

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Identification and characterization of innate lymphoid cells generated from pluripotent stem cells

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Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells

3
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination

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Neisseria species as pathobionts in bronchiectasis

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Aug 2022
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1960-html.html

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Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma

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Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis

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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

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Large-scale multiplexed mosaic CRISPR perturbation in the whole organism

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Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation

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B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation

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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

1
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Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function

1
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Apr 2022
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Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells

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Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse

1
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Mar 2022
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A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

1
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Distinct hepatic immunological patterns are associated with the progression or inhibition of hepatocellular carcinoma

1
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Feb 2022
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Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity

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Dec 2021
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Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity

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Sep 2021
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Protocol for analyzing and visualizing antiviral immune responses after acute infection of the murine oral mucosa

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Methods for Studying Mouse and Human Invariant Natural Killer T Cells

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  DOI: 10.1007/978-1-0716-1775-5_4
  
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Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

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Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

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Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection

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Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection

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Untitled document

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Untitled document

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A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

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A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection

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The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth

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Resident memory T cells in tumor-distant tissues fortify against metastasis formation

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A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

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Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

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Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response

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Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance

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Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint

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Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors

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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse

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Feb 2021
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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

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Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy

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Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection

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  DOI: 10.1016/j.celrep.2020.108567
  
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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

1
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  APC anti-mouse CD8a Antibody (clone 53–6.7)
  
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Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes

1
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PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction

1
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A Thermostable mRNA Vaccine against COVID-19

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Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

1
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Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

1
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts

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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth

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Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses

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IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection

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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

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HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

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Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

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Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment

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The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation

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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

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