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125 Matching Annotations

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Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.03.005
  
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sciencedirect.com/science/article/pii/S1074761326001160
Feb 2026
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Identifying microbial protease allergens through protein language model-guided homology

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.cels.2025.101510
  
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sciencedirect.com/science/article/pii/S2405471225003436
Jan 2026
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Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.043
  
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sciencedirect.com/science/article/pii/S0092867425014928
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TCF1lo CD8 T cells proliferate and persist autonomously in tumors

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1. scibot 27 Jan 2026
  
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  DOI: 10.64898/2026.01.17.700120
  
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biorxiv.org/content/10.64898/2026.01.17.700120v1
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Targeting senescent EGR1+ B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102532
  
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sciencedirect.com/science/article/pii/S2666379125006056
Dec 2025
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Dysplastic epithelial repair promotes the tissue residence of lymphocytes to inhibit alveolar regeneration post viral infection

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.stem.2025.12.005
  
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sciencedirect.com/science/article/pii/S1934590925004394
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Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer

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1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.neuron.2025.11.019
  
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sciencedirect.com:5037/science/article/pii/S089662732500892X
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ssrn-5775133-html.html

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  DOI: 10.2139/ssrn.5775133
  
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54.241.53.176/bd857ad9bf6b10dbc7c6d8f04f2ad72697088620/ssrn-5775133-html.html
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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.chom.2025.11.008
  
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sciencedirect.com:5037/science/article/pii/S1931312825004688
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Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy

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1. scibot 03 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.10.015
  
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sciencedirect.com:5037/science/article/pii/S1550413125004759
Oct 2025
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Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.biopha.2025.118697
  
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sciencedirect.com/science/article/pii/S0753332225008911
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102371
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12629800/
Sep 2025
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Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116350
  
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sciencedirect.com/science/article/pii/S2211124725011210
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OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis

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1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.cmet.2025.08.008
  
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sciencedirect.com/science/article/pii/S155041312500381X
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ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102336
  
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sciencedirect.com/science/article/pii/S2666379125004094
Aug 2025
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Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.08.001
  
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sciencedirect.com/science/article/pii/S1074761325003358
52.53.155.43 52.53.155.43

2025.08.13.669552v1.full-html.html

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1. scibot 22 Aug 2025
  
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  RRID:AB_312761
  
  DOI: 10.1101/2025.08.13.669552
  
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52.53.155.43/cbef6d49734833e21d46745b8a2764b4c745ed76/2025.08.13.669552v1.full-html.html
jeccr.biomedcentral.com jeccr.biomedcentral.com

TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

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1. scibot 19 Aug 2025
  
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  RRID:AB_312761
  
  DOI: 10.1186/s13046-025-03513-5
  
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jeccr.biomedcentral.com/articles/10.1186/s13046-025-03513-5
Jul 2025
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.006
  
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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
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Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.05.029
  
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sciencedirect.com/science/article/pii/S109727652500468X
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Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115800
  
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sciencedirect.com/science/article/pii/S2211124725005716
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma

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1. scibot 28 May 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0571
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12099492/
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PIM kinase control of CD8 T cell protein synthesis and cell trafficking

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.98622
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074636/
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Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.027
  
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sciencedirect.com/science/article/pii/S1074761325001906
Apr 2025
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Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115592
  
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sciencedirect.com/science/article/pii/S2211124725003638
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Tailoring an intravenously injectable oncolytic virus for augmenting radiotherapy

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102078
  
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sciencedirect.com/science/article/pii/S266637912500151X
Mar 2025
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BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.101995
  
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sciencedirect.com/science/article/pii/S2666379125000680
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IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis

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1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.005
  
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cell.com/immunity/fulltext/S1074-7613(25)00073-1
Feb 2025
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

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1. scibot 13 Feb 2025
  
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  DOI: 10.1126/scitranslmed.adj9366
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
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NFAT single-deficient murine T cells reduce the risk of aGvHD while controlling cytomegalovirus infection

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  DOI: 10.1016/j.isci.2025.111937
  
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sciencedirect.com/science/article/pii/S258900422500197X
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Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis

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  DOI: 10.1016/j.celrep.2025.115284
  
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sciencedirect.com/science/article/pii/S2211124725000555
Jan 2025
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Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation

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1. scibot 28 Jan 2025
  
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  DOI: 10.1016/j.celrep.2025.115241
  
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sciencedirect.com/science/article/pii/S2211124725000129
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Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

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1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.chom.2024.12.017
  
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High-resolution mapping of cell cycle dynamics during steady-state T cell development and regeneration in vivo

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115132
  
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sciencedirect.com/science/article/pii/S2211124724014839
Dec 2024
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Protocol to study ex vivo T cell priming by conventional dendritic cells from the mouse spleen

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1. scibot 19 Dec 2024
  
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  DOI: 10.1016/j.xpro.2024.103382
  
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sciencedirect.com/science/article/pii/S2666166724005471
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Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115015
  
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sciencedirect.com/science/article/pii/S2211124724013664
Nov 2024
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Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection

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DHDH-mediated D-xylose metabolism induces immune evasion in triple-negative breast cancer

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Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry

1
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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity

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Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation

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IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling

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Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling

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  DOI: 10.1126/scisignal.adh0439
  
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Mar 2024
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Adipose stem cells control obesity-induced T cell infiltration into adipose tissue

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ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis

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Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression

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CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis

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Nov 2023
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E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

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Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells

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High-resolution mapping of cell-cycle dynamics during steady-state T-cell development and regeneration in vivo

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Sep 2023
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Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis

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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

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Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment

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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion

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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

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NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection

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Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis

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DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

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Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

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T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62

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  DOI: 10.1158/1541-7786.MCR-21-0560
  
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Jun 2022
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Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function

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  DOI: 10.1158/0008-5472.CAN-21-3155
  
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aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
May 2022
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Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers

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  DOI: 10.1016/j.xpro.2022.101408
  
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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

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Apr 2022
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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

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Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

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Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

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Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo

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Interferon-γ promotes monocyte-mediated lung injury during influenza infection

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Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease

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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

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A defective viral genome strategy elicits broad protective immunity against respiratory viruses

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The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1

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Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice

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Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment

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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

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Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction

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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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Untitled document

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Untitled document

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Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells

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Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma

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Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response

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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development

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Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population

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Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation

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Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M

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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

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Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response

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Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice

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Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

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Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis

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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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Dec 2020
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Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses

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Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade

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Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity

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Critical role of WNK1 in MYC-dependent early mouse thymocyte development

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Sep 2020
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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

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Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms

1
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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

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Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip

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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

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C9orf72 in myeloid cells suppresses STING-induced inflammation

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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

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Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens

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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

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Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues

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Untitled document

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Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism

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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

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CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells

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Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.

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Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes

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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy

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