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    Protocol to study ex vivo T cell priming by conventional dendritic cells from the mouse spleen
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  3. Dec 2024
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    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
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  5. Nov 2024
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    Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection
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    DHDH-mediated D-xylose metabolism induces immune evasion in triple-negative breast cancer
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  8. Sep 2024
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    Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry
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  10. Aug 2024
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
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  13. Jul 2024
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    Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation
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  15. Apr 2024
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
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  18. Mar 2024
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    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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  21. Feb 2024
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    Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression
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  23. Jan 2024
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    CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
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  25. Nov 2023
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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  27. Oct 2023
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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  29. 52.53.155.43 52.53.155.43
    High-resolution mapping of cell-cycle dynamics during steady-state T-cell development and regeneration in vivo
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  30. Sep 2023
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    Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis
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  32. Aug 2023
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    An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases
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    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment
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  36. Jul 2023
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    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
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    Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion
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  39. Jun 2023
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    METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells
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  41. Apr 2023
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    NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection
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  43. Feb 2023
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    Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
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    DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development
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  46. Jan 2023
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    Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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  50. Oct 2022
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    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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  52. Jul 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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    ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
  54. Jun 2022
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    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
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    aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
  56. May 2022
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    Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers
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    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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  59. Apr 2022
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    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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  61. Mar 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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      DOI: 10.7554/eLife.75508

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    ncbi.nlm.nih.gov/pmc/articles/PMC8871394/
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    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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      DOI: 10.7554/eLife.69982

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    ncbi.nlm.nih.gov/pmc/articles/PMC8860447/
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    Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo
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  66. Dec 2021
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    Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease
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    Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
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  70. Nov 2021
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    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment
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  74. Oct 2021
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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  77. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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  79. Aug 2021
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    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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  81. Jul 2021
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    Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells
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    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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  86. Jun 2021
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    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
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  88. May 2021
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    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population
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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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    Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M
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    Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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    Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice
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  96. Apr 2021
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  100. Dec 2020
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    Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses
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  102. Nov 2020
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    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
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  105. Oct 2020
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  107. Sep 2020
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    Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
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  115. Jan 2020
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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    Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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      DOI: 10.1016/j.celrep.2019.05.020

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  119. www.sciencedirect.com www.sciencedirect.com
    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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    1. scibot 13 Jan 2020
      RRID:AB_312761

      DOI: 10.1016/j.molcel.2019.08.005

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    Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues
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      RRID:AB_312761

      DOI: 10.1016/j.celrep.2019.02.034

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    1. scibot 12 Jan 2020
      RRID:AB_312761

      DOI: 10.1016/j.immuni.2019.04.010

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    sciencedirect.com/science/article/pii/S1074761319301906
  122. Nov 2018
  123. www.sciencedirect.com www.sciencedirect.com
    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    1. scibot 05 Nov 2018
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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    1. scibot 05 Nov 2018
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      Curator: @evieth

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  127. europepmc.org europepmc.org
    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
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    Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes
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    sciencedirect.com/science/article/pii/S1074761317304776
  129. Nov 2017
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    Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
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    1. scibot 08 Nov 2017
      RRID:AB_312761

      Curator: @Jmenke

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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC5173323/