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  1. Last 7 days
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    Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation
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    1. scibot 20 Jul 2024
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  3. Apr 2024
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
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  6. Mar 2024
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    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    sciencedirect.com/science/article/pii/S1535610824000540
  9. Feb 2024
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    Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression
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    sciencedirect.com/science/article/pii/S2211124724000822
  11. Jan 2024
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    CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
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  13. Nov 2023
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    sciencedirect.com/science/article/pii/S2211124723014894
  15. Oct 2023
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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  17. 52.53.155.43 52.53.155.43
    High-resolution mapping of cell-cycle dynamics during steady-state T-cell development and regeneration in vivo
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  18. Sep 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis
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    1. scibot 29 Sep 2023
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    sciencedirect.com/science/article/pii/S0091674923009818
  20. Aug 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10439247/
  22. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    1. scibot 17 Aug 2023
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment
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  24. Jul 2023
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    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
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    Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion
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    sciencedirect.com/science/article/pii/S1934590923002138
  27. Jun 2023
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    METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells
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    sciencedirect.com/science/article/pii/S2211124723006952
  29. Apr 2023
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    NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection
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  31. Feb 2023
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    Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
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    sciencedirect.com/science/article/pii/S1074761323000432
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    DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development
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    sciencedirect.com/science/article/pii/S2211124723001171
  34. Jan 2023
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    Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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  38. Oct 2022
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    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    sciencedirect.com/science/article/pii/S1074761322005088
  40. Jul 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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      DOI: 10.1158/1541-7786.MCR-21-0560

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
  42. Jun 2022
  43. aacrjournals.org aacrjournals.org
    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
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    aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
  44. May 2022
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    Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers
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    sciencedirect.com/science/article/pii/S266616672200288X
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    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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  47. Apr 2022
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    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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    sciencedirect.com/science/article/pii/S1074761322001364
  49. Mar 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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      DOI: 10.7554/eLife.75508

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    ncbi.nlm.nih.gov/pmc/articles/PMC8871394/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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      DOI: 10.7554/eLife.69982

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    ncbi.nlm.nih.gov/pmc/articles/PMC8860447/
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    Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo
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    sciencedirect.com/science/article/pii/S245194562200085X
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    Interferon-γ promotes monocyte-mediated lung injury during influenza infection
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    sciencedirect.com/science/article/pii/S2211124722001838
  54. Dec 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease
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    sciencedirect.com/science/article/pii/S2211124721016703
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    Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
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    sciencedirect.com/science/article/pii/S0092867421013337
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A defective viral genome strategy elicits broad protective immunity against respiratory viruses
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598942/
  58. Nov 2021
  59. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice
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      DOI: 10.1038/s41598-021-02062-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC8604965/
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    Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment
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  62. Oct 2021
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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  65. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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  67. Aug 2021
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    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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  69. Jul 2021
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    Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells
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    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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  74. Jun 2021
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    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
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  76. May 2021
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    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population
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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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    Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M
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    Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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    Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice
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  84. Apr 2021
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  88. Dec 2020
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    Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses
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  90. Nov 2020
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    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
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  93. Oct 2020
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    Critical role of WNK1 in MYC-dependent early mouse thymocyte development
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  95. Sep 2020
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    Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization
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    Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
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    Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
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  103. Jan 2020
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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    Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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    Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues
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  110. Nov 2018
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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      RRID:AB_312761
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    ncbi.nlm.nih.gov/pmc/articles/PMC5728720/
  115. europepmc.org europepmc.org
    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
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    1. scibot 05 Nov 2018
      RRID:AB_312761

      Curator: @evieth

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      RRID:AB_312761 RRIDCUR:Validated
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    europepmc.org/articles/PMC5629024/
  116. www.sciencedirect.com www.sciencedirect.com
    Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes
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    1. scibot 05 Nov 2018
      RRID:AB_312761

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    sciencedirect.com/science/article/pii/S1074761317304776
  117. Nov 2017
  118. www.sciencedirect.com www.sciencedirect.com
    Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
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    1. scibot 08 Nov 2017
      RRID:AB_312761

      Curator: @Jmenke

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      (BioLegend Cat# 100722, RRID:AB_312761)

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      RRID:AB_312761 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761317303151
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy
    1
    1. scibot 08 Nov 2017
      AB_312761

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      (BioLegend Cat# 100722, RRID:AB_312761)

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      RRID:AB_312761
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    ncbi.nlm.nih.gov/pmc/articles/PMC5173323/