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The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.neuron.2025.09.032
  
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sciencedirect.com/science/article/pii/S0896627325007457
Oct 2025
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In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102399
  
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sciencedirect.com/science/article/pii/S2666379125004720
Sep 2025
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A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.08.015
  
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sciencedirect.com/science/article/pii/S1074761325003784
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Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis

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1. scibot 10 Sep 2025
  
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  DOI: 10.1101/2025.08.30.673054
  
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biorxiv.org/content/10.1101/2025.08.30.673054v1
Aug 2025
52.53.155.43 52.53.155.43

ssrn-5383300-html.html

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  DOI: 10.2139/ssrn.5383300
  
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52.53.155.43/811f1b02601013bf14721aa495ee0812e53b8878/ssrn-5383300-html.html
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Bifidobacterium animalis suppresses non-small cell lung cancer progression and modulates tumor immunity through indole-3-acetic acid

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116132
  
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sciencedirect.com/science/article/pii/S2211124725009039
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
Jul 2025
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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sciencedirect.com/science/article/pii/S1074761325002808
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Indole-3-lactic acid suppresses colorectal cancer via metabolic reprogramming

1
1. scibot 31 May 2025
  
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  DOI: 10.1080/19490976.2025.2508949
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12118437/
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SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages

1
1. scibot 19 May 2025
  
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  DOI: 10.1016/j.ymthe.2024.03.025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11081920/
Apr 2025
elifesciences.org elifesciences.org

Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice

1
1. scibot 19 Apr 2025
  
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  DOI: 10.7554/eLife.100581
  
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elifesciences.org/articles/100581
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Tailoring an intravenously injectable oncolytic virus for augmenting radiotherapy

1
1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102078
  
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sciencedirect.com/science/article/pii/S266637912500151X
Mar 2025
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IL-24 promotes atopic dermatitis-like inflammation through driving MRSA-induced allergic responses

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1. scibot 18 Mar 2025
  
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  DOI: 10.1093/procel/pwae030
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11892005/
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225003037-main-html.html

1
1. scibot 20 Feb 2025
  
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  AB_312790
  
  DOI: 10.1016/j.isci.2025.112043
  
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52.53.155.43/3dd3cafa6eaa243b57db8603cc2d3fd3d1e8448b/1-s2.0-S2589004225003037-main-html.html
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225000720-main-html.html

1
1. scibot 23 Jan 2025
  
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  RRID:AB_312790
  
  DOI: 10.1016/j.isci.2025.111812
  
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52.53.155.43/f4fe749bda5943afa72c94738ad741d8e2a2f94c/1-s2.0-S2589004225000720-main-html.html
Dec 2024
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Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity

1
1. scibot 21 Dec 2024
  
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  RRID:AB_312790
  
  DOI: 10.1101/2024.07.17.603931
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11275733/
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Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells

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1. scibot 02 Dec 2024
  
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  RRID:AB_312790
  
  DOI: 10.1016/j.celrep.2024.115023
  
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sciencedirect.com/science/article/pii/S2211124724013743
Nov 2024
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A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.xcrm.2024.101823
  
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sciencedirect.com/science/article/pii/S2666379124005949
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Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.immuni.2024.10.002
  
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sciencedirect.com/science/article/pii/S1074761324004825
Sep 2024
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Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.008
  
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sciencedirect.com/science/article/pii/S1535610824003076
Aug 2024
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Naive primary neutrophils play a dual role in the tumor microenvironment

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110632
  
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sciencedirect.com/science/article/pii/S2589004224018571
Jun 2024
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Microglia protect against age-associated brain pathologies

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.neuron.2024.05.018
  
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sciencedirect.com/science/article/pii/S0896627324003659
May 2024
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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

2
1. scibot 31 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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2. scibot 31 May 2024
  
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  RRID:AB_312790
  
  DOI: 10.1016/j.immuni.2024.05.006
  
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sciencedirect.com/science/article/pii/S1074761324002590
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PUS1 regulates erythropoiesis via tRNA pseudouridylation and cytoplasmic translation

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1. scibot 09 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109265
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10915626/
Dec 2023
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Subcutaneous white adipose tissue independently regulates burn-induced hypermetabolism via immune-adipose crosstalk

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113584
  
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sciencedirect.com/science/article/pii/S2211124723015966
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Prothymosin α accelerates dengue virus-induced thrombocytopenia

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108422
  
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sciencedirect.com/science/article/pii/S2589004223024999
Nov 2023
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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses

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1. scibot 18 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108348
  
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sciencedirect.com/science/article/pii/S2589004223024252
Oct 2023
52.53.155.43 52.53.155.43

SSRN-id4540281-html.html

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1. scibot 07 Oct 2023
  
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  DOI: 10.2139/ssrn.4540281
  
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52.53.155.43/72bad1538c1a67187d728f0cf48027e5fa4142ed/SSRN-id4540281-html.html
Sep 2023
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Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow

1
1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113127
  
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sciencedirect.com/science/article/pii/S2211124723011397
Aug 2023
52.53.155.43 52.53.155.43

PIIS2211124723009671-html.html

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112956
  
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52.53.155.43/0930b1a126a7ba8f04174ca993466b0fe3a7955f/PIIS2211124723009671-html.html
Jul 2023
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Tumor aerobic glycolysis confers immune evasion through modulating sensitivity to T cell-mediated bystander killing via TNF-α

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1. scibot 28 Jul 2023
  
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  DOI: 10.1016/j.cmet.2023.07.001
  
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sciencedirect.com/science/article/abs/pii/S1550413123002516
Jun 2023
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PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior

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1. scibot 22 Jun 2023
  
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  DOI: 10.1016/j.neuron.2023.05.022
  
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sciencedirect.com/science/article/pii/S0896627323003951
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Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation

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1. scibot 03 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112583
  
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sciencedirect.com/science/article/pii/S2211124723005946
Mar 2023
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Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow

1
1. scibot 03 Mar 2023
  
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  RRID:AB_312790
  
  DOI: 10.1016/j.devcel.2023.02.003
  
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sciencedirect.com/science/article/pii/S153458072300045X
Feb 2023
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Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease

1
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Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner

1
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The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

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  DOI: 10.1016/j.xcrm.2022.100893
  
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Dec 2022
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Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

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Commensal cow Roseburia reduces gut-dysbiosis-induced mastitis through inhibiting bacterial translocation by producing butyrate in mice

1
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Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning

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Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment

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Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection

1
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Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress

1
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A humanized β2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo

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Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

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Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue

1
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Aedes aegypti sialokinin facilitates mosquito blood feeding and modulates host immunity and vascular biology

1
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mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment

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Mar 2022
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A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

1
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Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases

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Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

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Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses

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In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

1
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Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy

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Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes

1
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Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation

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Aug 2021
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Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

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Untitled document

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Jul 2021
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Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons

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Untitled document

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Apr 2021
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The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies

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Feb 2021
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Cardiolipin-mediated PPARγ S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia

1
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

1
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SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

1
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HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation

1
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Jan 2020
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Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21

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EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection

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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

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Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

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1. scibot 13 Jan 2020
  
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  RRID:AB_312790
  
  DOI: 10.1016/j.ccell.2019.03.005
  
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sciencedirect.com/science/article/pii/S1535610819301503
Nov 2018
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A Combination of Ontogeny and CNS Environment Establishes Microglial Identity

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sciencedirect.com/science/article/pii/S0896627318303866
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Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

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Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity

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Nov 2017
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Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections

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sciencedirect.com/science/article/pii/S1074761317301826

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