193 Matching Annotations
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    Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation
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    1. scibot 20 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724006934
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    Immunogen characterization reveals an intrinsic hindrance in eliciting neutralizing antibodies against JN.1 variant
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    sciencedirect.com/science/article/pii/S2589004224016304
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    Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
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      DOI: 10.1016/j.ccell.2024.06.001

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    cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
  5. Jul 2024
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    Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine
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    sciencedirect.com/science/article/pii/S2211124724008192
  7. Jun 2024
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    Protein-energy restriction-induced lipid metabolism disruption causes stable-to-progressive disease shift in Mycobacterium avium-infected female mice
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    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2352396424002330
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    Epithelial uptake leads to fungal killing in vivo and is aberrant in COPD-derived epithelial cells
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    1. scibot 08 Jun 2024
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    sciencedirect.com/science/article/pii/S2589004224011611
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    Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
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    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S0092867424004926
  11. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    1. scibot 31 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002590
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    Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
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    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S1931312824001409
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    Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation
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    1. scibot 21 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002279
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    Sufficient Water Intake Maintains the Gut Microbiota and Immune Homeostasis and Promotes Pathogen Elimination
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    1. scibot 09 May 2024
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    Next-generation anti-PD-L1/IL-15 immunocytokine elicits superior antitumor immunity in cold tumors with minimal toxicity
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    1. scibot 02 May 2024
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    sciencedirect.com/science/article/pii/S2666379124002003
  17. Apr 2024
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    LKB1 prevents ILC2 exhaustion to enhance antitumor immunity
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    1. scibot 26 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124723015917
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    Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy
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    1. scibot 24 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004698
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    Selenoprotein I is indispensable for ether lipid homeostasis and proper myelination
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    sciencedirect.com/science/article/pii/S0021925824017605
  21. Mar 2024
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    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    1. scibot 27 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003231
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    Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection
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    sciencedirect.com/science/article/pii/S0092867424002496
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    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
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    sciencedirect.com/science/article/pii/S2211124724002912
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    The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling
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      DOI: 10.1084/jem.20221466

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    ncbi.nlm.nih.gov/pmc/articles/PMC10499045/
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    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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    sciencedirect.com/science/article/pii/S1535610824000485
  27. Feb 2024
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    Downregulation of IRF8 in alveolar macrophages by G-CSF promotes metastatic tumor progression
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    sciencedirect.com/science/article/pii/S2589004224004085
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    Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Cytosolic Material from Surrounding Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879714/
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    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    sciencedirect.com/science/article/pii/S2211124724001153
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens
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    ncbi.nlm.nih.gov/pmc/articles/PMC10867665/
  32. Jan 2024
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    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
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      DOI: 10.1016/j.cell.2023.12.011

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    sciencedirect.com/science/article/pii/S0092867423013430
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    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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    sciencedirect.com/science/article/pii/S2666379123006031
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    CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
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    sciencedirect.com/science/article/pii/S2211124723016194
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    FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10772350/
  37. Dec 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intestinal dysbiosis as an intraoperative predictor of septic complications: evidence from human surgical cohorts and preclinical models of peritoneal sepsis
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      DOI: 10.1038/s41598-023-49034-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10739899/
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    Sensory neurons promote immune homeostasis in the lung
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    sciencedirect.com/science/article/pii/S0092867423013132
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    Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies
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    sciencedirect.com/science/article/pii/S2666379123005530
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    Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
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    sciencedirect.com/science/article/pii/S1074761323004879
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    Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity
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    sciencedirect.com/science/article/pii/S2211124723015279
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    Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition
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    sciencedirect.com/science/article/pii/S0092867423012710
  44. Nov 2023
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    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis
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    sciencedirect.com/science/article/pii/S2211124723014614
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    load045-html.html
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      DOI: 10.1093/lifemeta/load045

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    52.53.155.43/4bb6da84d53e4cdc8c564457038a97934b92472d/load045-html.html
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    Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies
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      DOI: 10.1016/j.cell.2023.10.022

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    sciencedirect.com/science/article/pii/S009286742301173X
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    Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine
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  49. Oct 2023
  50. www.embopress.org www.embopress.org
    Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis
    1
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      DOI: 10.15252/embr.202357653

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  51. www.embopress.org www.embopress.org
    IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells
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      DOI: 10.15252/emmm.202317713

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  52. www.sciencedirect.com www.sciencedirect.com
    Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells
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  53. www.sciencedirect.com www.sciencedirect.com
    An early glycolysis burst in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuroinflammation
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  54. www.cell.com www.cell.com
    A micro-electroporation/electrophoresis-based vaccine screening system reveals the impact of vaccination orders on cross-protective immunity
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
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  56. Sep 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing
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  58. www.sciencedirect.com www.sciencedirect.com
    Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity
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    Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8
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  60. Aug 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases
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  62. www.sciencedirect.com www.sciencedirect.com
    Chronic HDM exposure shows time-of-day and sex-based differences in inflammatory response associated with lung circadian clock disruption
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-27 mediates immune response of pneumococcal vaccine SPY1 through Th17 and memory CD4+T cells
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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  65. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
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  66. Jul 2023
  67. www.sciencedirect.com www.sciencedirect.com
    Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells
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    Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
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  69. 52.53.155.43 52.53.155.43
    Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice
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      DOI: 10.1101/2023.05.31.543159

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  70. www.sciencedirect.com www.sciencedirect.com
    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic distinction between functional tissue-resident and conventional natural killer cells
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  72. Jun 2023
  73. www.sciencedirect.com www.sciencedirect.com
    Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s
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  74. May 2023
  75. jnm.snmjournals.org jnm.snmjournals.org
    Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment
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  76. www.sciencedirect.com www.sciencedirect.com
    Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases
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    Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection
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  78. Apr 2023
  79. www.sciencedirect.com www.sciencedirect.com
    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
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    CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue
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    Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
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    The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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  85. Mar 2023
  86. www.sciencedirect.com www.sciencedirect.com
    The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis
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  87. Feb 2023
  88. www.sciencedirect.com www.sciencedirect.com
    The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
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    Crosstalk between ILC2s and Th2 cells varies among mouse models
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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis
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  91. Jan 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses
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      DOI: 10.1158/0008-5472.CAN-21-0633

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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
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  96. Dec 2022
  97. www.sciencedirect.com www.sciencedirect.com
    Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis
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  99. Nov 2022
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    Interferon partly dictates a divergent transcriptional response in poxvirus-infected and bystander inflammatory monocytes
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    Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
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    Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses
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    Identification and characterization of innate lymphoid cells generated from pluripotent stem cells
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  104. Oct 2022
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    Efficient antigen delivery by dendritic cell-targeting peptide via nucleolin confers superior vaccine effects in mice
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  106. Sep 2022
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    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
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    Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury
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    Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection
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    Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis
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    Protocol to evaluate cell lineage stability of mouse natural and induced regulatory T cells using bisulfite sequencing
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    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
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    Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota
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    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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    Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
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    Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling the flux of the TCA cycle
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  120. May 2022
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    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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  123. Mar 2022
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    Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation
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    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection
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    Distinct hepatic immunological patterns are associated with the progression or inhibition of hepatocellular carcinoma
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  128. Feb 2022
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    ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression
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    Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics
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    A purine metabolic checkpoint that prevents autoimmunity and autoinflammation
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  133. Dec 2021
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    DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus
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  135. Nov 2021
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    Distinct contributions of partial and full EMT to breast cancer malignancy
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    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy
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    IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2
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    Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection
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    Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes
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    In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission
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    The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression
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    Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses <i>in vitro</i> and <i>in vivo</i>
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    A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire
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    IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice
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    Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma
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    Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy
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    Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity
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    B Cell Speed and B-FDC Contacts in Germinal Centers Determine Plasma Cell Output via Swiprosin-1/EFhd2
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  200. Jan 2020
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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  203. journals.plos.org journals.plos.org
    Inflammatory monocytes provide a niche for Salmonella expansion in the lumen of the inflamed intestine
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    Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
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    Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity
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    A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus
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    A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation
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    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
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  211. Nov 2018
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    Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
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    A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses
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    Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
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    Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling
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    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
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    High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease
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    Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
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    Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation
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    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
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  227. Nov 2017
  228. wellcomeopenresearch.org wellcomeopenresearch.org
    Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses <i>in vitro</i> and <i>in vivo</i>
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    O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection
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    Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy
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    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth
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    Expression Analysis of CB2-GFP BAC Transgenic Mice
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      AB_312801

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    Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model
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