46 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsets
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    1. scibot 18 Dec 2024
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      DOI: 10.1016/j.isci.2024.111248

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    sciencedirect.com/science/article/pii/S2589004224024738
  3. Dec 2024
  4. www.nature.com www.nature.com
    Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice
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    1. scibot 06 Dec 2024
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      DOI: 10.1038/s42003-024-07312-0

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    nature.com/articles/s42003-024-07312-0
  5. Oct 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-mediated myelin recycling fuels brain cancer malignancy
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    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.cell.2024.07.030

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    ncbi.nlm.nih.gov/pmc/articles/PMC11429458/
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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    1. scibot 27 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004774
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    Dynamic allostery drives autocrine and paracrine TGF-β signaling
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    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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    1. scibot 23 Aug 2024
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      DOI: 10.7554/eLife.76940

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  12. www.science.org www.science.org
    Artificial mucus layer formed in response to ROS for the oral treatment of inflammatory bowel disease
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    1. scibot 18 Aug 2024
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      DOI: 10.1126/sciadv.ado8222

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    science.org/doi/10.1126/sciadv.ado8222
  13. Jul 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Artificial mucus layer formed in response to ROS for the oral treatment of inflammatory bowel disease
    1
    1. scibot 31 Jul 2024
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      DOI: 10.1126/sciadv.ado8222

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    ncbi.nlm.nih.gov/pmc/articles/PMC11277472/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ATP-exporting channel Pannexin 1 promotes CD8+ T cell effector and memory responses
    1
    1. scibot 26 Jul 2024
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      DOI: 10.1016/j.isci.2024.110290

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    ncbi.nlm.nih.gov/pmc/articles/PMC11263643/
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis
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    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.ebiom.2024.105102

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    sciencedirect.com/science/article/pii/S2352396424001373
  18. Mar 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling
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    1. scibot 16 Mar 2024
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      DOI: 10.1084/jem.20221466

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    ncbi.nlm.nih.gov/pmc/articles/PMC10499045/
  20. Feb 2024
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
    1
    1. scibot 06 Feb 2024
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    sciencedirect.com/science/article/pii/S1550413124000068
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells
    1
    1. scibot 01 Feb 2024
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      DOI: 10.3390/biomedicines12010137

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    ncbi.nlm.nih.gov/pmc/articles/PMC10813358/
  23. Jan 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.chom.2023.12.006

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    sciencedirect.com/science/article/pii/S1931312823005012
  25. Aug 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1038/s43856-023-00336-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
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    Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.immuni.2023.07.014

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    sciencedirect.com/science/article/pii/S1074761323003278
  28. Jul 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance
    1
    1. scibot 08 Jul 2023
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      DOI: 10.7554/eLife.80443

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    ncbi.nlm.nih.gov/pmc/articles/PMC10325719/
  30. Apr 2023
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1002/advs.202206768

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    onlinelibrary.wiley.com/doi/10.1002/advs.202206768
  32. Mar 2023
  33. europepmc.org europepmc.org
    mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
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    1. scibot 22 Mar 2023
      RRID:AB_312861

      DOI: 10.1016/j.xcrm.2023.100978

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    europepmc.org/article/med/36933554
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    Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
    1
    1. scibot 16 Mar 2023
      RRID:AB_312861

      DOI: 10.1016/j.ccell.2023.02.005

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    sciencedirect.com/science/article/pii/S1535610823000338
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    A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages
    1
    1. scibot 16 Mar 2023
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2023.112253

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    sciencedirect.com/science/article/pii/S2211124723002644
  36. Feb 2023
  37. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
    1. scibot 03 Feb 2023
      RRID:AB_312861

      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  38. Dec 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation
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    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111741

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    sciencedirect.com/science/article/pii/S2211124722016199
  40. Nov 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses
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    1. scibot 03 Nov 2022
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2022.111563

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    sciencedirect.com/science/article/pii/S2211124722014243
  42. Sep 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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    1. scibot 13 Sep 2022
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      DOI: 10.1016/j.xcrm.2022.100744

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    sciencedirect.com/science/article/pii/S2666379122002932
  44. May 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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    1. scibot 12 May 2022
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      DOI: 10.1016/j.cell.2022.04.019

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    sciencedirect.com/science/article/pii/S0092867422004664
  46. Apr 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110727

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    sciencedirect.com/science/article/pii/S2211124722004880
  48. www.sciencedirect.com www.sciencedirect.com
    Autocrine and paracrine IL-2 signals collaborate to regulate distinct phases of CD8 T cell memory
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    1. scibot 14 Apr 2022
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2022.110632

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    sciencedirect.com/science/article/pii/S2211124722003849
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity
    1
    1. scibot 07 Apr 2022
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      DOI: 10.7554/eLife.70848

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983048/
  50. Feb 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity
    1
    1. scibot 16 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110384

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    sciencedirect.com/science/article/pii/S221112472200105X
  52. Nov 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    1. scibot 10 Nov 2021
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2021.109921

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    sciencedirect.com/science/article/pii/S2211124721013942
  54. Jul 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis
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    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.celrep.2019.01.054

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    sciencedirect.com/science/article/pii/S221112471930083X
  56. www.sciencedirect.com www.sciencedirect.com
    Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function
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    1. scibot 07 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109339

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    sciencedirect.com/science/article/pii/S2211124721007154
  57. May 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection
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      DOI: 10.1016/j.celrep.2021.109160

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    sciencedirect.com/science/article/pii/S2211124721005027
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    Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke
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    1. scibot 20 May 2021
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      DOI: 10.1016/j.immuni.2021.04.022

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    sciencedirect.com/science/article/pii/S1074761321001849
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.celrep.2021.109076

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    sciencedirect.com/science/article/pii/S2211124721004071
  61. Apr 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
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    1. scibot 24 Apr 2021
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      DOI: 10.1016/j.cell.2021.01.018

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    sciencedirect.com/science/article/pii/S0092867421000611
  63. www.sciencedirect.com www.sciencedirect.com
    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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    1. scibot 01 Apr 2021
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      DOI: 10.1016/j.immuni.2021.03.007

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    sciencedirect.com/science/article/pii/S1074761321001199
  64. Mar 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
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    1. scibot 26 Mar 2021
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2021.108894

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    sciencedirect.com/science/article/pii/S2211124721002084
  66. Sep 2020
  67. www.sciencedirect.com www.sciencedirect.com
    Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation
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      DOI: 10.1016/j.celrep.2020.107819

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    sciencedirect.com/science/article/pii/S2211124720308007
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    Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells
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    1. scibot 03 Sep 2020
      RRID:AB_312861

      DOI: 10.1016/j.immuni.2020.02.006

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  69. Jan 2020
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    Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells
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    1. scibot 13 Jan 2020
      RRID:AB_312861

      DOI: 10.1016/j.ccell.2019.10.006

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    Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells
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    1. scibot 13 Jan 2020
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2019.05.110

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    Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis
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    1. scibot 13 Jan 2020
      RRID:AB_312861

      DOI: 10.1016/j.celrep.2019.01.054

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  73. Nov 2018
  74. www.sciencedirect.com www.sciencedirect.com
    The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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  75. Nov 2017
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    Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
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      Curator: @Jmenke

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