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Bcl11a orchestrates multilineage integrity in aging hematopoiesis by regulating multipotent progenitor fate decisions

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1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117716
  
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sciencedirect.com/science/article/pii/S2211124726007941
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Autophagy maintains high endothelial venule identity and function during inflammation

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1. scibot 20 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.020
  
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sciencedirect.com/science/article/pii/S1074761326002712
Jul 2026
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Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially regulate T-cell phenotype and function

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1. scibot 14 Jul 2026
  
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  DOI: 10.1093/jimmun/vkag165
  
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dx.doi.org/10.1093/jimmun/vkag165
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Cribriform plate microenvironment assembles a suppressive myeloid network during EAE-induced neuroinflammation

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1. scibot 12 Jul 2026
  
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  DOI: 10.7554/eLife.110460
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13345627/
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Tobemstomig, a novel bispecific antibody, preferentially blocks PD-1 and LAG-3 on CD8 TILs to expand stem-like T-cells for sustained tumor control

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0207
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13347385/
Jun 2026
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The CD49b (ITGA2) collagen receptor excludes CD8+ T cell infiltration in pancreatic ductal adenocarcinoma

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.isci.2026.116500
  
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Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.cell.2026.05.036
  
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Catalpol Reactivates IL-7R–STAT5 Signaling and Reverses Radiation-Induced T Helper 1 Cells Deficiency to Limit Melanoma Metastasis to Lung

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1. scibot 13 Jun 2026
  
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  DOI: 10.1177/15347354261453338
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13237464/
May 2026
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Functional xenogeneic hematopoietic cells maintaining donor-dominant identity and immune tolerance enable therapy

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1. scibot 27 May 2026
  
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  DOI: 10.1186/s40164-026-00767-3
  
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link.springer.com/article/10.1186/s40164-026-00767-3
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Fungal metabolite-based immunotherapy overcomes tumor-associated macrophage immunosuppression

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1. scibot 27 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102833
  
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FOXA1-mediated CEPT1 deficiency in airway epithelium drives asthma via an ER stress-mitochondrial dysfunction axis

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1. scibot 27 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117368
  
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sciencedirect.com/science/article/pii/S2211124726004468
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Hyocholic acids shape neonatal immune tolerance and microbiota assembly

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1. scibot 21 May 2026
  
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  DOI: 10.1016/j.cmet.2026.04.016
  
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VSIG4 restricts hepatocellular carcinoma control by suppressing tumor-specific CD8+ T cell immunity in the tumor microenvironment

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1. scibot 05 May 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0836
  
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aacrjournals.org/cancerimmunolres/article/14/5/718/784454/VSIG4-Restricts-Hepatocellular-Carcinoma-Control
Apr 2026
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Homeostatic mature dendritic cells instruct fibroblast specialization via Notch2 signaling to establish T cell niches

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.023
  
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sciencedirect.com/science/article/pii/S1074761326001342
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Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.ccell.2026.03.020
  
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Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity

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1. scibot 09 Apr 2026
  
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  AB_312981
  
  DOI: 10.1158/1078-0432.CCR-24-3455
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13056295/
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Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.xcrm.2026.102717
  
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sciencedirect.com/science/article/pii/S2666379126001345
Mar 2026
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Insufficient erythrocyte-derived S1P: A pathogenic driver and diagnostic biolipid for tumor progression

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115216
  
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sciencedirect.com/science/article/pii/S2589004226005912
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6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.neuron.2026.02.028
  
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sciencedirect.com/science/article/pii/S0896627326001339
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Psoriasis modulates inflammatory bowel disease risk and intestinal epithelium lipid metabolism via IL-1β-producing macrophages

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.cmet.2026.02.014
  
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In vivo CAR-Tfh cell reprogramming restores tolerance in a mouse model of autoimmune hepatitis

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.02.006
  
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sciencedirect.com/science/article/pii/S1934590926000767
Feb 2026
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Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.003
  
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Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2025.102545
  
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Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.ccell.2026.01.005
  
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sciencedirect.com/science/article/pii/S1535610826000449
Jan 2026
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Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis

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1. scibot 15 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.032
  
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p57 increases immunotherapy efficacy by promoting cGAS-STING-mediated innate sensing in hepatocellular carcinoma

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116769
  
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Deletion of the Mouse Homolog of Human FHR1 (muFHR1) Alleviates Atherosclerosis in ApoE-/- mice

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1. scibot 06 Jan 2026
  
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  DOI: 10.7150/ijms.114990
  
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medsci.org/v23p0585.htm
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Discovery, delineation, and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102531
  
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5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation

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1. scibot 05 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102537
  
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sciencedirect.com/science/article/pii/S266637912500610X
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

A dysregulated hepcidin-iron axis impairs antiviral immunity and induces lethal liver pathology in neonates

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.001
  
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Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti–PD-1 Immunotherapy

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1. scibot 03 Dec 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3095
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12666320/
Nov 2025
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Autologous Thymic Organoids Support Functional T-cell Education and Enhance Antitumor Immunity in Humanized Mice with Melanoma Xenografts

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1. scibot 26 Nov 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0357
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12641387/
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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116526
  
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sciencedirect.com/science/article/pii/S2211124725012975
Oct 2025
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Intravascular immune surveillance against viremia requires spatiotemporal coordination between Kupffer cells and ILC1s

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116488
  
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An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer

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1. scibot 17 Oct 2025
  
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  RRID:AB_312981
  
  DOI: 10.1158/0008-5472.CAN-25-0822
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12502211/
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2025.09.30.679035v1.full-html.html

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Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis

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S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis

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Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

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Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity

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Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene

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Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment

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Inhibition of ACVR1 in Cancer-Associated Fibroblasts Suppresses Colorectal Cancer Cell Growth

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Interferon-driven CAF reprogramming augments immunogenic response to neoadjuvant radiotherapy in colorectal cancer

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A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis

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Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation

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DOCK8 in T cells promotes Th17 and Treg cell functionality to restrain mucosal mast cells and limit susceptibility to oral anaphylaxis

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Gene-regulatory programs that specify age-related differences during thymocyte development

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Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease

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The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis

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Piezo1 senses hyphae and initiates host defense against pathogenic fungi

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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

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Overcoming NK-mediated rejection by anti-3rd-party central memory veto CD8 T cells through downregulation of DNAM-1 on alloreactive NK cells

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The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions

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Combination therapy with alisertib enhances the anti-tumor immunity induced by a liver cancer vaccine

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STING Agonist VB-85247 Induces Durable Antitumor Immune Responses by Intravesical Administration in a Non–Muscle-Invasive Bladder Cancer

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BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity

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The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function

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Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

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The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2

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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma

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Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration

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A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination

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cir-24-0484-html.html

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The microglial response to inhibition of Colony-stimulating-factor-1 receptor by PLX3397 differs by sex in adult mice

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Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugates

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Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

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PDF-html.html

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Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion

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Fibroblast-Mediated Macrophage Recruitment Supports Acute Wound Healing

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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

1
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  DOI: 10.1016/j.ccell.2024.11.008
  
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

1
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  DOI: 10.1016/j.celrep.2024.115039
  
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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

1
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  DOI: 10.1016/j.celrep.2024.115056
  
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Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism

1
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
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  DOI: 10.1016/j.cmet.2024.10.015
  
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Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection

1
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  DOI: 10.1016/j.celrep.2024.114951
  
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Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis

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  DOI: 10.1016/j.isci.2024.111144
  
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A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier

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  DOI: 10.1158/0008-5472.CAN-19-3911
  
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aacrjournals.org/cancerres/article/81/3/619/648134/A-High-Content-Screen-Identifies-Drugs-That
Sep 2024
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The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

1
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  DOI: 10.7554/eLife.39982
  
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Aug 2024
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Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cells

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Fecal microbiota transplantation improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers refractory to anti-PD-1 inhibitor

1
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  DOI: 10.1016/j.chom.2024.06.010
  
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Innate immune memory after brain injury drives inflammatory cardiac dysfunction

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  DOI: 10.1016/j.cell.2024.06.028
  
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The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells

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Dietary fiber alleviates alcoholic liver injury via Bacteroides acidifaciens and subsequent ammonia detoxification

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Primary nasal influenza infection rewires tissue-scale memory response dynamics

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PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101649
  
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CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus

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  DOI: 10.1016/j.celrep.2024.114434
  
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Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE2 production

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  RRID:AB_312981
  
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A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism

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  DOI: 10.1016/j.isci.2024.110169
  
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STING orchestrates the neuronal inflammatory stress response in multiple sclerosis

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  RRID:AB_312981
  
  DOI: 10.1016/j.cell.2024.05.031
  
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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

1
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  RRID:AB_312981
  
  DOI: 10.1016/j.celrep.2024.114300
  
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May 2024
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An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination

1
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  DOI: 10.1016/j.immuni.2024.05.005
  
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G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds

2
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  RRID:AB_312981
  
  DOI: 10.1016/j.celrep.2024.114288
  
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  DOI: 10.1016/j.celrep.2024.114288
  
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Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

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  DOI: 10.7554/eLife.87756
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11111218/
Apr 2024
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CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

1
1. scibot 30 Apr 2024
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2024.04.003
  
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QDPR deficiency drives immune suppression in pancreatic cancer

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  RRID:AB_312981
  
  DOI: 10.1016/j.cmet.2024.03.015
  
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Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis

1
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  DOI: 10.1158/0008-5472.CAN-23-1542
  
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aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
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Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity

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  DOI: 10.1016/j.immuni.2024.03.017
  
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An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

1
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  Biolegend103116
  
  DOI: 10.1016/j.celrep.2024.114020
  
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Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood

1
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  DOI: 10.1016/j.devcel.2024.03.019
  
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MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue

1
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  DOI: 10.1016/j.celrep.2024.113978
  
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IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model

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  DOI: 10.1038/s41467-024-45870-3
  
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Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells

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  RRID:AB_312981
  
  DOI: 10.1016/j.celrep.2024.113954
  
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  DOI: 10.1016/j.celrep.2024.113954
  
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Type-I-interferon-responsive microglia shape cortical development and behavior

2
1. scibot 15 Mar 2024
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.cell.2024.02.020
  
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  DOI: 10.1016/j.cell.2024.02.020
  
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Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC

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  DOI: 10.1016/j.celrep.2024.113767
  
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Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

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Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells

1
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  DOI: 10.3390/biomedicines12010137
  
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Nov 2023
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E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

1
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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

1
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Oct 2023
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CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions

1
1. scibot 24 Oct 2023
  
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  DOI: 10.1101/2023.10.10.561700
  
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Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors

2
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Renal tubular epithelial cells are constitutive non-cognate stimulators of resident T cells

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  DOI: 10.1016/j.celrep.2023.113210
  
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SSRN-id4540281-html.html

1
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  DOI: 10.2139/ssrn.4540281
  
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Sep 2023
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Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow

1
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Protocol for high-sensitivity western blot on murine hematopoietic stem cells

1
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Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden

1
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Deletion of the inhibitory co-receptor CTLA4 enhances and invigorates chimeric antigen receptor T cells

1
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Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis

1
1. scibot 29 Sep 2023
  
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  DOI: 10.1016/j.jaci.2023.07.015
  
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Aug 2023
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Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome

1
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Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

1
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Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice

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Jun 2023
52.53.155.43 52.53.155.43

Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of Alveolar Macrophages

1
1. scibot 30 Jun 2023
  
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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

1
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ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression

1
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MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis

1
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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer

1
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  DOI: 10.1016/j.isci.2023.106916
  
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Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer

1
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  DOI: 10.1016/j.celrep.2023.112533
  
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May 2023
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

1
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  DOI: 10.1016/j.ccell.2023.04.019
  
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The enteric nervous system relays psychological stress to intestinal inflammation

1
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells

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  DOI: 10.1002/advs.202204378
  
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Apr 2023
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Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells

1
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  DOI: 10.1016/j.celrep.2023.112431
  
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A tissue injury sensing and repair pathway distinct from host pathogen defense

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  DOI: 10.1016/j.cell.2023.03.031
  
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The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation

1
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  DOI: 10.1016/j.immuni.2023.03.021
  
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An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses

1
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  DOI: 10.1016/j.medj.2023.03.007
  
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Mar 2023
europepmc.org europepmc.org

Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination

1
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  DOI: 10.1016/j.celrep.2023.112293
  
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europepmc.org/article/med/36952346
Feb 2023
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Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer

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  DOI: 10.15252/embr.202256524
  
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Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

1
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  DOI: 10.1016/j.immuni.2023.01.023
  
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A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

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  DOI: 10.1016/j.immuni.2023.01.028
  
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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes

1
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Identification of the mouse Kupffer cell receptors recognizing pneumococcal capsules by affinity screening

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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

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ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

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Nov 2022
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DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

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Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4

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Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis

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TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

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Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

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Sep 2022
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Neisseria species as pathobionts in bronchiectasis

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Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis

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Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection

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Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

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Lymphatics act as a signaling hub to regulate intestinal stem cell activity

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A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis

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May 2022
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Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

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Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model

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Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

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Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction

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Mar 2022
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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2

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A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

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Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target

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Protocol for influenza A virus infection of mice and viral load determination

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Jan 2022
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Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses

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CRISPitope: A generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models

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Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

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Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development

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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

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  DOI: 10.1016/j.cell.2021.11.018
  
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Nov 2021
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Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

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Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor

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COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver

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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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Sep 2021
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Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction

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Protocol for analyzing and visualizing antiviral immune responses after acute infection of the murine oral mucosa

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  DOI: 10.1016/j.xpro.2021.100790
  
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Senescent immune cells release grancalcin to promote skeletal aging

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1. scibot 14 Sep 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.cmet.2021.08.009
  
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sciencedirect.com/science/article/pii/S1550413121003727
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The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis

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1. scibot 18 Aug 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2021.06.008
  
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Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection

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1. scibot 18 Aug 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.celrep.2021.109538
  
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Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency

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1. scibot 16 Aug 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.isci.2021.102833
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8326191/
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1. scibot 11 Aug 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2017.11.003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5759774/
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  DOI: 10.1016/j.stem.2016.10.004
  
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cell.com/cell-stem-cell/abstract/S1934-5909(16)30344-7
academic.oup.com academic.oup.com

Untitled document

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1. scibot 07 Aug 2021
  
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  RRID:AB_312981
  
  DOI: 10.1210/en.2018-00600
  
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academic.oup.com/endo/article/159/11/3848/5105924
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  DOI: 10.1016/j.celrep.2018.12.072
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6334226/
Jul 2021
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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

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1. scibot 31 Jul 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.chom.2019.03.003
  
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2. scibot 28 Jul 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.chom.2019.03.003
  
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Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability

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  CD45‐APC/Cy7
  
  DOI: 10.1002/ijc.32594
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.32594
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Standard screening methods underreport AAV-mediated transduction and gene editing

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1. scibot 29 Jul 2021
  
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  APC-Cy7
  
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nature.com/articles/s41467-019-11321-7
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  DOI: 10.1016/j.celrep.2018.12.002
  
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GABA-receptive microglia selectively sculpt developing inhibitory circuits

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.06.018
  
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DHX15 is required to control RNA virus-induced intestinal inflammation

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1. scibot 23 Jun 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.celrep.2021.109205
  
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May 2021
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Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology

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1. scibot 28 May 2021
  
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  103116
  
  DOI: 10.1126/sciadv.abe4601
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8139596/
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Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

1
1. scibot 07 May 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2020.12.004
  
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Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow

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1. scibot 06 May 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2020.07.017
  
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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2021.04.001
  
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Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation

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1. scibot 04 May 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.immuni.2021.03.024
  
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cell.com/immunity/fulltext/S1074-7613(21)00136-9
Apr 2021
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Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation

1
1. scibot 28 Apr 2021
  
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  RRID:AB_312981
  
  DOI: 10.1016/j.celrep.2021.109052
  
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sciencedirect.com/science/article/pii/S2211124721003685

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