162 Matching Annotations
  1. Last 7 days
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    Dietary fiber alleviates alcoholic liver injury via Bacteroides acidifaciens and subsequent ammonia detoxification
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    sciencedirect.com/science/article/pii/S1931312824002269
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    Primary nasal influenza infection rewires tissue-scale memory response dynamics
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    sciencedirect.com/science/article/pii/S107476132400311X
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    PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
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    sciencedirect.com/science/article/pii/S266637912400363X
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    CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
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    cell.com/cell-reports/abstract/S2211-1247(24)00763-0
  6. Jul 2024
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    Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE2 production
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    sciencedirect.com/science/article/pii/S2211124724007988
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    A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism
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    sciencedirect.com/science/article/pii/S2589004224013944
  9. Jun 2024
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    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
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    sciencedirect.com/science/article/pii/S0092867424005762
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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
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    sciencedirect.com/science/article/pii/S2211124724006284
  12. May 2024
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    An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination
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    sciencedirect.com/science/article/pii/S1074761324002589
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    G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds
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    sciencedirect.com/science/article/pii/S2211124724006168
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    Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
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    1. scibot 24 May 2024
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      DOI: 10.7554/eLife.87756

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    ncbi.nlm.nih.gov/pmc/articles/PMC11111218/
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S1074761324002085
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    QDPR deficiency drives immune suppression in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1550413124001190
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    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
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      DOI: 10.1158/0008-5472.CAN-23-1542

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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
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    Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity
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    sciencedirect.com/science/article/pii/S1074761324001389
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    An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
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    sciencedirect.com/science/article/pii/S2211124724003486
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    Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood
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    sciencedirect.com/science/article/pii/S1534580724001874
  23. Mar 2024
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    MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue
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    sciencedirect.com/science/article/pii/S2211124724003061
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    IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model
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    nature.com/articles/s41467-024-45870-3
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    Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells
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    sciencedirect.com/science/article/pii/S2211124724002821
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    Type-I-interferon-responsive microglia shape cortical development and behavior
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    sciencedirect.com/science/article/pii/S0092867424001867
  28. Feb 2024
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    Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC
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    sciencedirect.com/science/article/pii/S2211124724000950
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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    sciencedirect.com/science/article/pii/S1550413124000068
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells
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      DOI: 10.3390/biomedicines12010137

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    ncbi.nlm.nih.gov/pmc/articles/PMC10813358/
  32. Nov 2023
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    sciencedirect.com/science/article/pii/S2211124723014894
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    sciencedirect.com/science/article/pii/S2211124723013645
  35. Oct 2023
  36. www.biorxiv.org www.biorxiv.org
    CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
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      DOI: 10.1101/2023.10.10.561700

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    biorxiv.org/content/10.1101/2023.10.10.561700v1
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    Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors
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    52.53.155.43/7eb24570d443d458f8fd7700f91970ed0d945838/2023.08.11.553007v1.full-html.html
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    Renal tubular epithelial cells are constitutive non-cognate stimulators of resident T cells
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    sciencedirect.com/science/article/pii/S2211124723012226
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    SSRN-id4540281-html.html
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    52.53.155.43/72bad1538c1a67187d728f0cf48027e5fa4142ed/SSRN-id4540281-html.html
  40. Sep 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow
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    sciencedirect.com/science/article/pii/S2211124723011397
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for high-sensitivity western blot on murine hematopoietic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10519847/
  43. www.sciencedirect.com www.sciencedirect.com
    Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden
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      DOI: 10.1016/j.ccell.2023.09.006

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    sciencedirect.com/science/article/abs/pii/S1535610823003227
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    Deletion of the inhibitory co-receptor CTLA4 enhances and invigorates chimeric antigen receptor T cells
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      DOI: 10.1016/j.immuni.2023.09.001

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    sciencedirect.com/science/article/pii/S1074761323004077
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    Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis
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      DOI: 10.1016/j.jaci.2023.07.015

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    sciencedirect.com/science/article/pii/S0091674923009818
  46. Aug 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome
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    sciencedirect.com/science/article/pii/S221112472301001X
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
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      DOI: 10.1038/s43856-023-00336-3

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    Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice
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  50. Jun 2023
  51. 52.53.155.43 52.53.155.43
    Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of Alveolar Macrophages
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    METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells
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    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression
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    MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis
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    Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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  57. May 2023
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells
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  61. Apr 2023
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    Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells
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    The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
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    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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  66. Mar 2023
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    Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
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  68. Feb 2023
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    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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    Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes
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    A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages
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  72. Jan 2023
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    Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes
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    Identification of the mouse Kupffer cell receptors recognizing pneumococcal capsules by affinity screening
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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  76. Dec 2022
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    ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury
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  78. Nov 2022
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    DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability
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    Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4
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    Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis
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  82. Oct 2022
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    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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    Neisseria species as pathobionts in bronchiectasis
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    Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis
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    Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection
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  91. Jun 2022
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    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
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    Lymphatics act as a signaling hub to regulate intestinal stem cell activity
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    A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis
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  95. May 2022
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    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
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    Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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  99. Apr 2022
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    Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction
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  101. Mar 2022
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    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2
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    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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  105. Feb 2022
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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      DOI: 10.1038/s41467-022-28372-y

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  107. www.sciencedirect.com www.sciencedirect.com
    Protocol for influenza A virus infection of mice and viral load determination
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  108. Jan 2022
  109. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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    CRISPitope: A generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models
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    Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
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  112. Dec 2021
  113. elifesciences.org elifesciences.org
    Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
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  114. www.sciencedirect.com www.sciencedirect.com
    Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
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  115. Nov 2021
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    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor
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    COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver
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  119. Oct 2021
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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  121. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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    Protocol for analyzing and visualizing antiviral immune responses after acute infection of the murine oral mucosa
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    Senescent immune cells release grancalcin to promote skeletal aging
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  125. Aug 2021
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    The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis
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    Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC8326191/
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  130. www.cell.com www.cell.com
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  131. academic.oup.com academic.oup.com
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  133. Jul 2021
  134. www.sciencedirect.com www.sciencedirect.com
    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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      DOI: 10.1016/j.chom.2019.03.003

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  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
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      CD45‐APC/Cy7

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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32594
  136. www.nature.com www.nature.com
    Standard screening methods underreport AAV-mediated transduction and gene editing
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  138. www.sciencedirect.com www.sciencedirect.com
    GABA-receptive microglia selectively sculpt developing inhibitory circuits
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  139. Jun 2021
  140. www.sciencedirect.com www.sciencedirect.com
    DHX15 is required to control RNA virus-induced intestinal inflammation
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  141. May 2021
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology
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    Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium
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    Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow
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    Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection
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    Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation
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    sciencedirect.com/science/article/pii/S1074761321001369
  147. Apr 2021
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    Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation
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    CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis
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    Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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  152. Mar 2021
  153. elifesciences.org elifesciences.org
    Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis
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      DOI: 10.7554/eLife.61798

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    Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging
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    Genome-wide analysis of pseudogenes reveals HBBP1’s human-specific essentiality in erythropoiesis and implication in β-thalassemia
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  156. Feb 2021
  157. www.sciencedirect.com www.sciencedirect.com
    DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity
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    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
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    Protocol for human placental mesenchymal stem cell therapy in a murine model of intra-abdominal infection of hypervirulent Klebsiella
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  161. Nov 2020
  162. elifesciences.org elifesciences.org
    MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
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  163. Oct 2020
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    In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells
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  165. Sep 2020
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    Human Placental MSC-Secreted IL-1β Enhances Neutrophil Bactericidal Functions during Hypervirulent Klebsiella Infection
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    Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
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    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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    Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
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    The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
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    An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
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    Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
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    Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones
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    Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers
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  177. Jan 2020
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    Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
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    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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      DOI: 10.1016/j.immuni.2019.06.007

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    STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth
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    Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis
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    Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity
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    Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity
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    TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity
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    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
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    Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
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      DOI: 10.1016/j.immuni.2018.11.004

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    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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    Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes
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    Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance
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  192. Nov 2018
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis
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    Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection
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    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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    The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages
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    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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  199. Nov 2017
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    Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
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    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
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    Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis
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      (BioLegend Cat# 103116, RRID:AB_312981)

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      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_312981 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590916303447