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Heterogeneity and plasticity of the naive CD4+ T cell compartment

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116980
  
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sciencedirect.com/science/article/pii/S2211124726000586
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Photo‐Empowered Macrophage‐Based Drug Delivery System Overcomes Motility Suppression and Significantly Enhances Deep Tumor Drug Delivery

1
1. scibot 30 Jan 2026
  
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  RRID:AB_313
  
  DOI: 10.1002/advs.202515349
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12850126/
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Engineered probiotics recruit CAR macrophages and establish immune memory to eradicate heterogeneous glioblastoma in mice

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.chom.2025.12.014
  
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sciencedirect.com/science/article/pii/S1931312825005335
Dec 2025
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Dysplastic epithelial repair promotes the tissue residence of lymphocytes to inhibit alveolar regeneration post viral infection

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.stem.2025.12.005
  
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sciencedirect.com/science/article/pii/S1934590925004394
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The glycolytic reaction PGAM restrains Th17 pathogenicity and Th17-dependent autoimmunity

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1. scibot 22 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.115799
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12443480/
Aug 2025
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Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116177
  
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sciencedirect.com/science/article/pii/S2211124725009489
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225007692-main-html.html

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1. scibot 18 May 2025
  
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  AB_313099
  
  DOI: 10.1016/j.isci.2025.112508
  
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52.53.155.43/bf6cba30678d0d150a13cbeb68660b4f11367a41/1-s2.0-S2589004225007692-main-html.html
Apr 2025
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CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

1
1. scibot 08 Apr 2025
  
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  RRID:AB_313099
  
  DOI: 10.7554/eLife.103417
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970909/
Feb 2025
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A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy

1
1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115301
  
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sciencedirect.com/science/article/pii/S2211124725000725
Dec 2024
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

1
1. scibot 06 Dec 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
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A yeast-based oral therapeutic delivers immune checkpoint inhibitors to reduce intestinal tumor burden

1
1. scibot 02 Dec 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.chembiol.2024.10.013
  
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sciencedirect.com/science/article/pii/S2451945624004525
Oct 2024
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Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon

1
1. scibot 04 Oct 2024
  
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  DOI: 10.1016/j.cmet.2024.09.002
  
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sciencedirect.com/science/article/pii/S1550413124003668
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

1
1. scibot 25 Sep 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.ymthe.2024.05.038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405166/
Aug 2024
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Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II

1
1. scibot 27 Aug 2024
  
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  AB_313099
  
  DOI: 10.1016/j.celrep.2024.114655
  
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sciencedirect.com/science/article/pii/S2211124724010064
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

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1. scibot 23 Aug 2024
  
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  RRID:AB_313099
  
  DOI: 10.7554/eLife.76940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
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Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity

1
1. scibot 20 Aug 2024
  
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  AB_313099
  
  DOI: 10.1016/j.celrep.2024.114591
  
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sciencedirect.com/science/article/pii/S2211124724009203
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

1
1. scibot 20 Aug 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.cell.2024.07.016
  
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sciencedirect.com/science/article/pii/S0092867424007761
Jul 2024
www.cell.com www.cell.com

Fecal microbiota transplantation improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers refractory to anti-PD-1 inhibitor

1
1. scibot 30 Jul 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.chom.2024.06.010
  
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cell.com/cell-host-microbe/abstract/S1931-3128(24)00228-2
www.cell.com www.cell.com

Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

1
1. scibot 18 Jul 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.ccell.2024.06.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
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SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration

2
1. scibot 12 Jul 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2024.114458
  
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2. scibot 12 Jul 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2024.114458
  
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sciencedirect.com/science/article/pii/S2211124724007873
May 2024
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

1
1. scibot 14 May 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.cell.2024.04.023
  
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sciencedirect.com/science/article/pii/S0092867424004483
Apr 2024
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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

1
1. scibot 12 Apr 2024
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.xcrm.2024.101479
  
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sciencedirect.com/science/article/pii/S2666379124001253
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Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling

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1. scibot 02 Apr 2024
  
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  RRID:AB_313099
  
  DOI: 10.1126/scisignal.adh0439
  
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science.org/doi/10.1126/scisignal.adh0439
Dec 2023
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CD62L expression marks a functionally distinct subset of memory B cells

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1. scibot 20 Dec 2023
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2023.113542
  
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sciencedirect.com/science/article/pii/S2211124723015541
Aug 2023
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Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry

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1. scibot 18 Aug 2023
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.xpro.2023.102485
  
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sciencedirect.com/science/article/pii/S2666166723004525
52.53.155.43 52.53.155.43

CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

2
1. scibot 17 Aug 2023
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.xcrm.2023.101151
  
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2. scibot 11 Aug 2023
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.xcrm.2023.101151
  
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52.53.155.43/75914c2645b295883453ae6f0848b8ff04ccb7e0/PIIS266637912300304X-html.html
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

1
1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.immuni.2023.07.014
  
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sciencedirect.com/science/article/pii/S1074761323003278
Jul 2023
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Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.immuni.2023.06.025
  
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sciencedirect.com/science/article/pii/S1074761323002820
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Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

1
1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112864
  
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sciencedirect.com/science/article/pii/S2211124723008756
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Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation

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1. scibot 15 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107230
  
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sciencedirect.com/science/article/pii/S258900422301307X
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112813
  
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sciencedirect.com/science/article/pii/S2211124723008240
Jun 2023
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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

1
1. scibot 27 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112684
  
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sciencedirect.com/science/article/pii/S2211124723006952
May 2023
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Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection

1
1. scibot 10 May 2023
  
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  AB_313099
  
  DOI: 10.1016/j.immuni.2023.04.010
  
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sciencedirect.com/science/article/pii/S1074761323001796
Apr 2023
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SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis

1
1. scibot 27 Apr 2023
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.isci.2023.106644
  
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Mar 2023
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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

1
1. scibot 16 Mar 2023
  
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  RRID:AB_313
  
  DOI: 10.1016/j.immuni.2023.02.018
  
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Jan 2023
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Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes

1
1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.12.007
  
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PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype

1
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  DOI: 10.1016/j.isci.2022.105137
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9523278/
Aug 2022
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Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes

1
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  DOI: 10.1016/j.immuni.2022.07.019
  
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Jun 2022
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Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism

1
1. scibot 29 Jun 2022
  
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  DOI: 10.1016/j.immuni.2022.06.002
  
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Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses

1
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  DOI: 10.1016/j.celrep.2022.110901
  
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Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function

1
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  DOI: 10.1158/0008-5472.CAN-21-3155
  
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aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
May 2022
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Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8+ T cell exhaustion

1
1. scibot 21 May 2022
  
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  DOI: 10.1016/j.isci.2022.104347
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9117873/
Apr 2022
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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

1
1. scibot 13 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.013
  
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Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches

2
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  RRID:AB_313099
  
  DOI: 10.1016/j.immuni.2022.03.006
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.immuni.2022.03.006
  
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Mar 2022
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Mucus sialylation determines intestinal host-commensal homeostasis

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  DOI: 10.1016/j.cell.2022.02.013
  
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BPS Publications

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  DOI: 10.1111/bph.15780
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15780
Dec 2021
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Two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge

1
1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110112
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8610932/
Nov 2021
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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

1
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  DOI: 10.1016/j.isci.2021.103347
  
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sciencedirect.com/science/article/pii/S258900422101316X
Oct 2021
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Arthritis flares mediated by tissue-resident memory T cells in the joint

1
1. scibot 27 Oct 2021
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2021.109902
  
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sciencedirect.com/science/article/pii/S2211124721013723
Sep 2021
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Activating a collaborative innate-adaptive immune response to control metastasis

1
1. scibot 03 Sep 2021
  
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  DOI: 10.1016/j.ccell.2021.08.005
  
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sciencedirect.com/science/article/pii/S1535610821004451
Aug 2021
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ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis

1
1. scibot 25 Aug 2021
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2021.109602
  
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Untitled document

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1. scibot 13 Aug 2021
  
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  DOI: 10.7554/eLife.44210
  
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Untitled document

1
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  DOI: 10.1016/j.immuni.2018.10.008
  
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sciencedirect.com/science/article/pii/S1074761318304497
Jul 2021
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Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity

1
1. scibot 31 Jul 2021
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.immuni.2018.12.011
  
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T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

1
1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.cell.2018.10.008
  
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Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells

1
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  DOI: 10.1016/j.celrep.2021.109430
  
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Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function

1
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  DOI: 10.1016/j.celrep.2021.109339
  
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sciencedirect.com/science/article/pii/S2211124721007154
May 2021
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Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β

1
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sciencedirect.com/science/article/pii/S107476132030265X
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Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response

1
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  DOI: 10.1016/j.celrep.2021.109076
  
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sciencedirect.com/science/article/pii/S2211124721004071
Apr 2021
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Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice

1
1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.08.004
  
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sciencedirect.com/science/article/pii/S1550413120304174
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

1
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  DOI: 10.1016/j.immuni.2021.03.007
  
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sciencedirect.com/science/article/pii/S1074761321001199
Mar 2021
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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

1
1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108831
  
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sciencedirect.com/science/article/pii/S2211124721001455
Dec 2020
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Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation

1
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  DOI: 10.1016/j.celrep.2020.108452
  
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sciencedirect.com/science/article/pii/S2211124720314418
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation

1
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  DOI: 10.3389/fimmu.2020.02180
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7500101/
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

1
1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108085
  
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pubmed.ncbi.nlm.nih.gov/32877667/
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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

1
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  DOI: 10.1016/j.chom.2020.02.015
  
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sciencedirect.com/science/article/pii/S1931312820301232
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Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB

1
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  DOI: 10.1016/j.immuni.2019.01.004
  
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cell.com/immunity/abstract/S1074-7613(19)30004-4
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Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

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  DOI: 10.1016/j.chom.2020.03.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(20)30124-4
Jan 2020
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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2019.05.020
  
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  RRID:AB_313099 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112471930631X
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TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

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1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2019.05.061
  
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  RRID:AB_313099 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719306904
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Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

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1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.cell.2019.07.032
  
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  RRID:AB_313099 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419308311
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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

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1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2019.07.044
  
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sciencedirect.com/science/article/pii/S2211124719309416
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.cmet.2019.05.002
  
  Resource: (BioLegend Cat# 104412, RRID:AB_313099)
  
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sciencedirect.com/science/article/pii/S1550413119302426
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment

1
1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.cmet.2019.04.002
  
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  RRID:AB_313099 RRIDCUR:Validated
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pmc.ncbi.nlm.nih.gov/articles/PMC7061417/
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.celrep.2019.01.066
  
  Resource: (BioLegend Cat# 104412, RRID:AB_313099)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124719300956
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.immuni.2019.04.001
  
  Resource: (BioLegend Cat# 104412, RRID:AB_313099)
  
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  RRID:AB_313099 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319301815
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Untitled document

1
1. scibot 12 Jan 2020
  
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  RRID:AB_313099
  
  DOI: 10.1016/j.immuni.2019.01.004
  
  Resource: (BioLegend Cat# 104412, RRID:AB_313099)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_313099
  
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  RRID:AB_313099 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319300044
Nov 2018
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Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis

1
1. scibot 05 Nov 2018
  
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  RRID:AB_313099
  
  Resource used:
  
  (BioLegend Cat# 104412, RRID:AB_313099)
  
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sciencedirect.com/science/article/pii/S1074761318301924
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CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine

1
1. scibot 05 Nov 2018
  
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  RRID:AB_313099
  
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  (BioLegend Cat# 104412, RRID:AB_313099)
  
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  RRID:AB_313099
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sciencedirect.com/science/article/pii/S1934590918300171

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