75 Matching Annotations
  1. Last 7 days
  2. www.science.org www.science.org
    Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells
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    1. scibot 20 Dec 2024
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    science.org/doi/10.1126/scisignal.adi8753
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
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    1. scibot 09 Oct 2024
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    sciencedirect.com/science/article/pii/S1097276524007767
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
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    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.016

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    sciencedirect.com/science/article/pii/S0092867424007761
  7. Jul 2024
  8. www.cell.com www.cell.com
    Nynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening
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    1. scibot 16 Jul 2024
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00215-7
  9. Jun 2024
  10. www.biorxiv.org www.biorxiv.org
    Low abundant intestinal commensals modulate immune control of chronic myeloid leukemia stem cells
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    1. scibot 07 Jun 2024
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      DOI: 10.1101/2024.05.31.595679

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    biorxiv.org/content/10.1101/2024.05.31.595679v1
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate
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    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S193459092400047X
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution
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    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.005

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    sciencedirect.com/science/article/pii/S1550413123004564
  15. Dec 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Sensory neurons promote immune homeostasis in the lung
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    1. scibot 22 Dec 2023
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    sciencedirect.com/science/article/pii/S0092867423013132
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    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
    1
    1. scibot 01 Dec 2023
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    sciencedirect.com/science/article/pii/S221112472301464X
  18. Oct 2023
  19. www.embopress.org www.embopress.org
    Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL-1R/TLR signals
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    1. scibot 27 Oct 2023
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      DOI: 10.15252/embr.202357485

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    embopress.org/doi/10.15252/embr.202357485
  20. www.sciencedirect.com www.sciencedirect.com
    ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia
    1
    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723012184
  21. Sep 2023
  22. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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    1. scibot 19 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113084

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    sciencedirect.com/science/article/pii/S2211124723010951
  23. Aug 2023
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues
    2
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112924

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    pmc.ncbi.nlm.nih.gov/articles/PMC10504686/
  25. Jul 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production
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    1. scibot 01 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723007192
  27. Jun 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s
    1
    1. scibot 09 Jun 2023
      RRID:AB_311369

      DOI: 10.1016/j.celrep.2023.112610

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    sciencedirect.com/science/article/pii/S2211124723006216
  29. Mar 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery
    1
    1. scibot 24 Mar 2023
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      DOI: 10.1016/j.isci.2023.106341

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    sciencedirect.com/science/article/pii/S2589004223004182
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Skin γδ T cell inflammatory responses are hardwired in the thymus by oxysterol sensing via GPR183 and calibrated by dietary cholesterol
    1
    1. scibot 03 Mar 2023
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      DOI: 10.1016/j.immuni.2023.01.025

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    pmc.ncbi.nlm.nih.gov/articles/PMC10306310/
  32. Feb 2023
  33. www.sciencedirect.com www.sciencedirect.com
    A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2211124723001109
  34. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
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    1. scibot 03 Feb 2023
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    sciencedirect.com/science/article/pii/S153561082300003X
  35. Jan 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice
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    1. scibot 27 Jan 2023
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      DOI: 10.1016/j.isci.2023.105972

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838028/
  37. Oct 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype
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    1. scibot 04 Oct 2022
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      DOI: 10.1016/j.isci.2022.105137

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    ncbi.nlm.nih.gov/pmc/articles/PMC9523278/
  39. Sep 2022
  40. www.sciencedirect.com www.sciencedirect.com
    A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut
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    sciencedirect.com/science/article/pii/S1074761322004125
  41. May 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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    1. scibot 26 May 2022
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      DOI: 10.1016/j.stem.2022.04.017

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    sciencedirect.com/science/article/pii/S1934590922001709
  43. www.sciencedirect.com www.sciencedirect.com
    Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers
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    1. scibot 25 May 2022
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      DOI: 10.1016/j.xpro.2022.101408

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    sciencedirect.com/science/article/pii/S266616672200288X
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    1. scibot 11 May 2022
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      DOI: 10.1126/sciadv.abm9987

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    ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
  45. Apr 2022
  46. www.science.org www.science.org
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    1. scibot 30 Apr 2022
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      DOI: 10.1126/sciadv.abm9987

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    science.org/doi/full/10.1126/sciadv.abm9987
  47. Mar 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    1. scibot 26 Mar 2022
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    sciencedirect.com/science/article/pii/S1097276522002076
  49. Jan 2022
  50. www-sciencedirect-com.libproxy.snu.ac.kr www-sciencedirect-com.libproxy.snu.ac.kr
    Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells
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    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.immuni.2021.12.015

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    www-sciencedirect-com.libproxy.snu.ac.kr/science/article/pii/S1074761321005513
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    Correlation between circulating innate lymphoid cell precursors and thymic function
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    sciencedirect.com/science/article/pii/S2589004222000025
  52. Dec 2021
  53. insight.jci.org insight.jci.org
    Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
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      DOI: 10.1172/jci.insight.151797

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    insight.jci.org/articles/view/151797
  54. Nov 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    sciencedirect.com/science/article/pii/S2211124721015448
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
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      DOI: 10.7554/eLife.69621

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    ncbi.nlm.nih.gov/pmc/articles/PMC8585479/
  57. Oct 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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    sciencedirect.com/science/article/pii/S2211124721013577
  59. Sep 2021
  60. www.sciencedirect.com www.sciencedirect.com
    A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells
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    sciencedirect.com/science/article/pii/S1074761321003630
  61. Aug 2021
  62. www.sciencedirect.com www.sciencedirect.com
    A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
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    sciencedirect.com/science/article/pii/S221112472101010X
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8333149/
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    1. scibot 12 Aug 2021
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      DOI: 10.15252/embj.2018100293

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    onlinelibrary.wiley.com/doi/10.15252/embj.2018100293
  65. europepmc.org europepmc.org
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      DOI: 10.7554/eLife.41258

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    europepmc.org/articles/PMC6298771/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
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      DOI: 10.7554/eLife.69975

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    ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
  67. Jul 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.celrep.2019.03.105

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    Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
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    Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells
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  71. May 2021
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    Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
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    Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells
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    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
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  75. Apr 2021
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    Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint
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    Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis
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    Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
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  79. Feb 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy
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  81. insight.jci.org insight.jci.org
    Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation
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  82. Jan 2021
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    Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells
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    Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment
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  85. Oct 2020
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    Critical role of WNK1 in MYC-dependent early mouse thymocyte development
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    In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors
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  88. Sep 2020
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    Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
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    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
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    Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo
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    An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance
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  93. elifesciences.org elifesciences.org
    Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging
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    Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes
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  95. Jan 2020
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    Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
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    Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation
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    Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis
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    The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells
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    TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity
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  103. emboj.embopress.org emboj.embopress.org
    BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses
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      DOI: 10.15252/embj.2018100293

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  104. Nov 2018
  105. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
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    GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism
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    Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation
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    KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
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  109. Nov 2017
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
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    Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
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