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71 Matching Annotations

Sep 2026
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NAD+ precursor treatment prevents cardiomyopathy but disrupts erythroid maturation in mitochondrial progeria

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  DOI: 10.1016/j.celrep.2026.117849
  
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sciencedirect.com/science/article/pii/S2211124726009277
Jun 2026
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STAT3 interference-driven nanomodulators reverse lipid metabolism-associated chemoresistance and potentiate metalloimmunotherapy in breast cancer

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  DOI: 10.1016/j.xcrm.2026.102844
  
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sciencedirect.com/science/article/pii/S2666379126002612
May 2026
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miR-93-mediated PTEN suppression and CNS-specific T cell exhaustion shape the leukemia niche in infant KMT2A::AFF1+ B-ALL

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1. scibot 16 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117353
  
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sciencedirect.com/science/article/pii/S2211124726004316
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

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1. scibot 06 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102706
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
Apr 2026
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P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapy

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2159-8290.CD-25-1212
  
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aacrjournals.org/cancerdiscovery/article/16/3/571/774737/p21-Positive-Senescent-Stromal-Cells-Promote
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RORγt Inhibition Reduces Pro-Tumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer

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1. scibot 03 Mar 2026
  
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  DOI: 10.1158/2326-6066.CIR-24-1128
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12288671/
Feb 2026
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Fasting impairs humoral immunological memory by β-hydroxybutyrate-mediated depletion of plasma cells

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.002
  
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sciencedirect.com/science/article/pii/S1074761326000038
Jan 2026
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Uridine depletion impairs CD8⁺ T cell antitumor activity through N-glycosylation

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.cmet.2025.11.016
  
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sciencedirect.com/science/article/pii/S1550413125005303
Sep 2025
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Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116350
  
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sciencedirect.com/science/article/pii/S2211124725011210
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TNFSF15 alleviates myeloid-derived suppressor cell-mediated cancer immunosuppression in mice

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1. scibot 23 Sep 2025
  
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  DOI: 10.1038/s41401-025-01663-y
  
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nature.com/articles/s41401-025-01663-y
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Complement component C6 deficiency exacerbates colorectal tumorigenesis by abolishing membrane attack complex formation and potentiating M2-like tumor-associated macrophage responses

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.intimp.2025.115576
  
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sciencedirect.com/science/article/pii/S156757692501567X
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ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102336
  
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sciencedirect.com/science/article/pii/S2666379125004094
Aug 2025
www.tandfonline.com www.tandfonline.com

A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy

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1. scibot 21 Aug 2025
  
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  RRID:AB_313377
  
  DOI: 10.1080/2162402X.2025.2543620
  
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tandfonline.com/doi/full/10.1080/2162402X.2025.2543620
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Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.medj.2025.100804
  
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sciencedirect.com/science/article/pii/S2666634025002314
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
Jul 2025
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TAF1 is required for fetal but not adult hematopoiesis in mice

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1. scibot 17 Jul 2025
  
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  RRID:AB_313377
  
  DOI: 10.1016/j.devcel.2025.06.027
  
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sciencedirect.com/science/article/pii/S1534580725004058
Jun 2025
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Bivalent chromatin instructs lineage specification during hematopoiesis

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.cell.2025.05.011
  
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sciencedirect.com/science/article/pii/S0092867425005616
May 2025
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Ocular immune privilege in action: The living eye imposes unique regulatory and anergic gene signatures on uveitogenic T cells

1
1. scibot 31 May 2025
  
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  RRID:AB_313377
  
  DOI: 10.1016/j.celrep.2025.115780
  
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sciencedirect.com/science/article/pii/S2211124725005510
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Microbiota-derived urocanic acid triggered bytyrosine kinase inhibitors potentiates cancer immunotherapy efficacy

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1. scibot 29 May 2025
  
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  RRID:AB_313377
  
  DOI: 10.1016/j.chom.2025.04.022
  
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sciencedirect.com/science/article/pii/S1931312825001556
Apr 2025
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Intestinal-region-specific functions of AHR in intrinsic enteric neurons during infections

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115524
  
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sciencedirect.com/science/article/pii/S2211124725002955
Mar 2025
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PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy

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1. scibot 14 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.024
  
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sciencedirect.com/science/article/pii/S1535610825000765
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dynamic tracking of native precursors in adult mice

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1. scibot 11 Dec 2024
  
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  DOI: 10.7554/eLife.97504
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11620740/
Nov 2024
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IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy

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1. scibot 14 Nov 2024
  
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  RRID:AB_313377
  
  DOI: 10.1016/j.xcrm.2024.101826
  
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sciencedirect.com/science/article/pii/S2666379124005974
Oct 2024
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Alarmin-loaded extracellular lipid droplets induce airway neutrophil infiltration during type 2 inflammation

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1. scibot 04 Oct 2024
  
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  DOI: 10.1016/j.immuni.2024.09.001
  
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sciencedirect.com/science/article/pii/S107476132400445X
Sep 2024
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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.018
  
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sciencedirect.com/science/article/pii/S1535610824003179
Aug 2024
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Baf155 controls hematopoietic differentiation and regeneration through chromatin priming

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1. scibot 01 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114558
  
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sciencedirect.com/science/article/pii/S2211124724008878
Mar 2024
52.53.155.43 52.53.155.43

LC3-dependent extracellular vesicles (LDEVs) promote M-MDSC accumulation and immunosuppression in colorectal cancer.

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109272
  
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52.53.155.43/f6f930ecf0ad11fcfb4027b99fa0ee6fde8d8158/1-s2.0-S2589004224004930-main-html.html
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche

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1. scibot 07 Feb 2024
  
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  DOI: 10.1038/s41467-024-45471-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844594/
Jan 2024
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Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

2
1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.chembiol.2023.12.005
  
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  DOI: 10.1016/j.chembiol.2023.12.005
  
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sciencedirect.com/science/article/pii/S245194562300435X
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

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1. scibot 26 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101234
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10591062/
52.53.155.43 52.53.155.43

CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

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1. scibot 20 Oct 2023
  
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  DOI: 10.1101/2023.09.01.555931
  
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52.53.155.43/af30fe5b925ee191151336cec774a7057661b188/2023.09.01.555931v1.full-html.html
Aug 2023
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Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112990
  
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sciencedirect.com/science/article/pii/S221112472301001X
52.53.155.43 52.53.155.43

PTEN regulates hematopoietic lineage plasticity via PU.1-dependent chromatin accessibility

2
1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112967
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112967
  
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52.53.155.43/fc73699b69f68947fccc1396949d2b0acab3a956/PIIS2211124723009786-html.html
Mar 2023
europepmc.org europepmc.org

Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

1
1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.stem.2023.02.010
  
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europepmc.org/article/med/36948186
Oct 2022
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Immuno-localization of definitive hematopoietic stem cells in the vascular niche of mouse fetal liver

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1. scibot 13 Oct 2022
  
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

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  DOI: 10.1038/s41596-022-00713-7
  
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Dynamic trafficking patterns of IL-17-producing γδ T cells are linked to the recurrence of skin inflammation in psoriasis-like dermatitis

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Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy

1
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Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

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Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells

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  DOI: 10.1172/jci.insight.151797
  
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Resolving the immune landscape of human prostate at a single-cell level in health and cancer

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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

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Efferocytosis induces macrophage proliferation to help resolve tissue injury

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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

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Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges

1
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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

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The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

1
1. scibot 31 Jul 2021
  
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  DOI: 10.7554/eLife.39982
  
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May 2021
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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

1
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  DOI: 10.1016/j.immuni.2020.10.001
  
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Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells

1
1. scibot 26 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108894
  
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IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models

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  DOI: 10.3389/fimmu.2020.614667
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7897681/
Oct 2020
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Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function

1
1. scibot 27 Oct 2020
  
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Jan 2020
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Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium

1
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  DOI: 10.1016/j.celrep.2019.11.061
  
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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

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  DOI: 10.1016/j.molcel.2019.08.005
  
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Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.09.004
  
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The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

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TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity

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The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

1
1. scibot 12 Jan 2020
  
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Nov 2018
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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

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HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

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The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells

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The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

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ncbi.nlm.nih.gov/pmc/articles/PMC6104739/
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Untitled document

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A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

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Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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pmc.ncbi.nlm.nih.gov/articles/PMC6465538/
Nov 2017
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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

1
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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

1
1. scibot 08 Nov 2017
  
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